Abstract: A system for coupling a tendon to a bone may include a tendon coupling device engageable with a tendon, a fastener to secure the tendon coupling device to the tendon, a bone coupling device, and a flexible element. The flexible element may include a first portion and a second portion. The first portion of the flexible element may be couplable with the fastener to securably attach the flexible element to the tendon. The bone coupling device may include a bone-facing surface engageable with a surface of the bone proximate a bone tunnel formed through the bone, and a hole formed through the bone coupling device. The second portion of the flexible element may be receivable through the bone tunnel and the hole formed through the bone coupling device to engage an opposing surface of the bone coupling device and securably couple the tendon to the bone.

Abstract: The invention relates to inhibition of SDF-1? expression in subacromial bursa cells by CXCR-4 inhibitors. Bursal cell migration in response to SDF-? stimulation is also decreased in the presence of CXCR4 inhibitors. Accordingly, provided are methods for treating or ameliorating a musculoskeletal disorder.

Abstract: The invention relates to inhibition of SDF-1? expression in subacromial bursa cells by CXCR-4 inhibitors. Bursal cell migration in response to SDF-? stimulation is also decreased in the presence of CXCR4 inhibitors. Accordingly, provided are methods for treating or ameliorating a musculoskeletal disorder.

Abstract: The subject instruments are surgical retractors known as the Visiblade™ that can be anatomically “customized” for each surgical procedure. The retractors are single blade instruments which are comprised of plastic composite and semi-liquid (pliable) acrylic resin materials that can be formed in-situ to a desired configuration. Once configured, the retractor blade is exposed to a light source where the acrylic resin attains a rigid state. The retractors are single use (sterile), translucent, radiolucent and non-abrasive. They improve visualization, reduce risk of infection and minimize the need for multiple pre-formed retractor instruments during surgical procedures. The retractors are intended to be disposed after use and are made of materials that can be recycled.