Patents by Inventor Theodore C. Jessop

Theodore C. Jessop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating ulcerative colitis
    Patent number: 8404732
    Abstract: Methods of treating and managing ulcerative colitis, using imidazole-based compounds that inhibit S1P lyase, are disclosed.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: March 26, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Lakmal W. Boteju, Kenneth G. Carson, Theodore C. Jessop, Spencer David Kimball
  • METHODS OF TREATING ULCERATIVE COLITIS
    Publication number: 20130005775
    Abstract: Methods of treating and managing ulcerative colitis, using imidazole-based compounds that inhibit S1P lyase, are disclosed.
    Type: Application
    Filed: January 4, 2012
    Publication date: January 3, 2013
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Lakmal W. Boteju, Kenneth G. Carson, Theodore C. Jessop, Spencer David Kimball
  • 4-amino-1H-pyrimidin-2-one based compounds, compositions comprising them and methods of their use
    Patent number: 8093245
    Abstract: 4-Amino-1H-pyrimidin-2-one-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of various diseases and disorders are disclosed.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: January 10, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Marianne Carlsen, Kenneth G. Carson, Qinghong Fu, Alexander Heim-Riether, Theodore C. Jessop, James E. Tarver, Jerry A. Taylor
  • Methods of treating rheumatoid arthritis
    Patent number: 8093267
    Abstract: Imidazole-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: January 10, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Lakmal W. Boteju, Kenneth G. Carson, Theodore C. Jessop, Spencer David Kimball
  • O-linked pyrimidin-4-amine-based compounds, compositions comprising them, and methods of their use to treat cancer
    Patent number: 8093246
    Abstract: O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: January 10, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Marianne Carlsen, Kenneth G. Carson, Qinghong Fu, Jason P. Healy, Alexander Heim-Riether, Theodore C. Jessop, Philip E. Keyes, Min Shen, James E. Tarver, Jerry A. Taylor, Xiaolian Xu
  • METHODS OF TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES AND DISORDERS
    Publication number: 20110082178
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 7, 2011
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D.P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Heterocyclic compounds, compositions comprising them and methods of their use
    Patent number: 7825142
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: November 2, 2010
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D. P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • METHODS OF TREATING RHEUMATOID ARTHRITIS
    Publication number: 20100076030
    Abstract: Imidazole-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 25, 2010
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Lakmal W. Boteju, Kenneth G. Carson, Theodore C. Jessop, Spencer David Kimball
  • Imidazole-based compounds, compositions comprising them and methods of their use
    Patent number: 7649098
    Abstract: Imidazole-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: January 19, 2010
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Lakmal W. Boteju, Kenneth G. Carson, Theodore C. Jessop, Spencer David Kimball
  • HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20090312375
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: August 24, 2009
    Publication date: December 17, 2009
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D.P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Heterocyclic compounds, compositions comprising them and methods of their use
    Patent number: 7598280
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: October 6, 2009
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D. P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • Heterocyclic Compounds, Compositions Comprising Them and Methods of Their Use
    Publication number: 20090030050
    Abstract: Heterocyclic compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of inflammatory and autoimmune diseases and disorders are disclosed.
    Type: Application
    Filed: February 28, 2008
    Publication date: January 29, 2009
    Inventors: David J. Augeri, Jeffrey Bagdanoff, Simon D.P. Baugh, Kenneth G. Carson, Theodore C. Jessop, James E. Tarver
  • 4-AMINO-1H-PYRIMIDIN-2-ONE BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE
    Publication number: 20080182847
    Abstract: 4-Amino-1H-pyrimidin-2-one-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of various diseases and disorders are disclosed.
    Type: Application
    Filed: December 12, 2007
    Publication date: July 31, 2008
    Inventors: David J. Augeri, Marianne Carlsen, Kenneth G. Carson, Qinghong Fu, Alexander Heim-Riether, Theodore C. Jessop, James E. Tarver, Jerry A. Taylor
  • O-LINKED PYRIMIDIN-4-AMINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE TO TREAT CANCER
    Publication number: 20080146571
    Abstract: O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described.
    Type: Application
    Filed: December 12, 2007
    Publication date: June 19, 2008
    Inventors: David J. Augeri, Marianne Carlsen, Kenneth G. Carson, Qinghong Fu, Jason P. Healy, Alexander Heim-Riether, Theodore C. Jessop, Philip E. Keyes, Min Shen, James E. Tarver, Jerry A. Taylor, Xiaolian Xu
  • Guanidinium transport reagents and conjugates
    Patent number: 7169814
    Abstract: Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: January 30, 2007
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Cellgate, Inc.
    Inventors: Jonathan B. Rothbard, Paul A. Wender, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Bi-directional synthesis of oligoguanidine transport agents
    Patent number: 7067698
    Abstract: Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ?-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: June 27, 2006
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Paul A. Wender, Christopher L. VanDeusen, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Guanidinium transport reagents and conjugates
    Publication number: 20040161405
    Abstract: Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
    Type: Application
    Filed: December 11, 2002
    Publication date: August 19, 2004
    Inventors: Jonathan B. Rothbard, Paul A. Wender, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Guanidinium transport reagents and conjugates
    Publication number: 20030185788
    Abstract: Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
    Type: Application
    Filed: December 11, 2002
    Publication date: October 2, 2003
    Inventors: Jonathan B. Rothbard, Paul A. Wender, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Bi-directional synthesis of oligoguanidine transport agents
    Publication number: 20030073807
    Abstract: Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of &ohgr;-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.
    Type: Application
    Filed: August 2, 2002
    Publication date: April 17, 2003
    Inventors: Paul A. Wender, Christopher L. VanDeusen, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop