Abstract: This disclosure relates to an apparatus useful for the delivery of aerosols, such as those containing drugs, to the lungs or other locations in the body. The disclosure also relates to methods of administering an aerosol to the lungs or other locations in the body of a patient.

Abstract: This disclosure relates to an apparatus useful for the delivery of aerosols, such as those containing drugs, to the lungs or other locations in the body. The disclosure also relates to methods of administering an aerosol to the lungs or other locations in the body of a patient.

Abstract: This disclosure relates to an apparatus useful for the delivery of aerosols, such as those containing drugs, to the lungs or other locations in the body. The disclosure also relates to methods of administering an aerosol to the lungs or other locations in the body of a patient.

Abstract: An intrapulmonary aerosolizer comprises an aerosolizer attached to a pressure generator for delivery of liquid as an aerosol and which can be positioned in close proximity to the lungs by being inserted into the trachea directly or into an endotracheal tube or bronchoscope positioned within the trachea.

Abstract: An intrapulmonary aerosolizer comprises an aerosolizer attached to a pressure generator for delivery of liquid as an aerosol and which can be positioned in close proximity to the lungs by being inserted into the trachea directly or into an endotracheal tube or bronchoscope positioned within the trachea.

Abstract: An intrapulmonary aerosolizer comprises an aerosolizer attached to a pressure generator for delivery of liquid as an aerosol and which can be positioned in close proximity to the lungs by being inserted into the trachea directly or into an endotracheal tube or bronchoscope positioned within the trachea.

Abstract: A sub-miniature aerosolizer comprises a substantially elongated sleeve member, a substantially elongated insert and a substantially elongated body member. The sleeve member includes a threaded inner surface which is adapted to receive the insert which is a correspondingly threaded member. The threaded insert provides a substantially helical channel. The body member includes a cavity on its first end which terminates by an end wall at its second end. The end wall includes an orifice extending therethrough. The body member is connected with the sleeve member to provide the sub-miniature aerosolizer of the present invention. The sub-miniature aerosolizer is sized to accommodate insertion into the trachea of a subject for use of the device. For operation of the device, the sub-miniature aerosolizer is connected by a suitable tube with a liquid pressure driver apparatus. The liquid pressure driver apparatus is adapted to pass liquid material therefrom which is sprayed from the sub-miniature aerosolizer.

Abstract: A sub-miniature aerosolizer comprises a substantially elongated sleeve member, a substantially elongated insert and a substantially elongated body member. The sleeve member includes a threaded inner surface which is adapted to receive the insert which is a correspondingly threaded member. The threaded insert provides a substantially helical channel. The body member includes a cavity on its first end which terminates by an end wall at its second end. The end wall includes an orifice extending therethrough. The body member is connected with the sleeve member to provide the sub-miniature aerosolizer of the present invention. The sub-miniature aerosolizer is sized to accommodate insertion into the trachea of a subject for use of the device. For operation of the device, the sub-miniature aerosolizer is connected by a suitable tube with a liquid pressure driver apparatus. The liquid pressure driver apparatus is adapted to pass liquid material therefrom which is sprayed from the sub-miniature aerosolizer.

Abstract: A sub-miniature aerosolizer comprises a substantially elongated sleeve member, a substantially elongated insert and a substantially elongated body member. The sleeve member includes a threaded inner surface which is adapted to receive the insert which is a correspondingly threaded member. The threaded insert provides a substantially helical channel. The body member includes a cavity on its first end which terminates by an end wall at its second end. The end wall includes an orifice extending therethrough. The body member is connected with the sleeve member to provide the sub-miniature aerosolizer of the present invention. The sub-miniature aerosolizer is sized to accommodate insertion into the trachea of a subject for use of the device. For operation of the device, the sub-miniature aerosolizer is connected by a suitable tube with a liquid pressure driver apparatus. The liquid pressure driver apparatus is adapted to pass liquid material therefrom which is sprayed from the sub-miniature aerosolizer.

Abstract: A dispenser provides pulmonary delivery of a powder dose to a subject. The dispenser is adapted to be brought into connection with an actuator which introduces an amount of a gas for dispensing the powder dose. The dispenser includes a chamber for receiving the powder dose and a valve for permitting passage of the powder dose only when the actuator introduces the gas into the dispenser. The powder dose is passed from the dispenser for pulmonary delivery to the subject.

Abstract: A dispenser provides pulmonary delivery of a powder dose to a subject. The dispenser is adapted to be brought into connection with an actuator which introduces an amount of a gas for dispensing the powder dose. The dispenser includes a chamber for receiving the powder dose and a valve for permitting passage of the powder dose only when the actuator introduces the gas into the dispenser. The powder dose is passed from the dispenser for pulmonary delivery to the subject.

Abstract: A dispenser provides pulmonary delivery of a powder dose to a subject. The dispenser is adapted to be brought into connection with an actuator which introduces an amount of a gas for dispensing the powder dose. The dispenser includes a chamber for receiving the powder dose and a valve for permitting passage of the powder dose only when the actuator introduces the gas into the dispenser. The powder dose is passed from the dispenser for pulmonary delivery to the subject.

Abstract: A plethysmographic device is disclosed which is adapted for receiving a laboratory animal for measuring pulmonary ventilation thereof. The plethysmographic device includes a containment member which defines a sealed environment and which includes as portions thereof at least a first and a second member and a seal. The first member is adapted to releasably engage the second member with the seal defining a self-supporting radial seal being provided therebetween for defining the sealed environment of the containment member. The containment member also includes an inlet and an outlet. The inlet of the containment member is in communication with a supply which is adapted to regulate the environment of the containment member. The outlet of the containment member is in communication with a response device which is adapted for monitoring the environment of the containment member. The first member includes as portions thereof a receptacle, a platform, and a base.