Patents by Inventor Theodore John Nitz

Theodore John Nitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-3 novel triterpenone with C-28 urea derivatives as HIV inhibitors
    Patent number: 10669305
    Abstract: The present invention relates to C-3 novel triterpenone with C-28 urea derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, W, J and X are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) useful for the treatment of viral diseases and particularly HIV mediated diseases.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: June 2, 2020
    Assignee: HETERO LABS LIMITED
    Inventors: Parthasaradhi Reddy Bandi, Rathnakar Reddy Kura, David Krupadanam Gazula Levi, Panduranga Reddy Adulla, Bhaskar Reddy Kasireddy, Carl Thomas Wild, David Eugene Martin, Theodore John Nitz
  • C-3 novel triterpenone with C-28 amide derivatives as HIV inhibitors
    Patent number: 10370405
    Abstract: The invention relates to C-3 novel triterpenone with C-28 amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases (formula 1).
    Type: Grant
    Filed: March 12, 2016
    Date of Patent: August 6, 2019
    Assignee: HETERO LABS LIMITED
    Inventors: Parthasaradhi Reddy Bandi, Rathnakar Reddy Kura, David Krupadanam Gazula Levi, Panduranga Reddy Adulla, Eswara Rao Bammidi, Bhaskar Reddy Kasireddy, Sudhakar Neela, Carl Thomas Wild, David Eugene Martin, Theodore John Nitz
  • C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS
    Publication number: 20180305398
    Abstract: The present invention relates to C-3 novel triterpenone with C-28 urea derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, W, J and X are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) useful for the treatment of viral diseases and particularly HIV mediated diseases.
    Type: Application
    Filed: October 12, 2016
    Publication date: October 25, 2018
    Inventors: Parthasaradhi Reddy BANDI, Rathnakar Reddy KURA, David Krupadanam GAZULA LEVI, Panduranga Reddy ADULLA, Bhaskar Reddy KASIREDDY, Carl Thomas Wild, David Eugene Martin, Theodore John Nitz
  • C-3 NOVEL TRITERPENONE WITH C-28 AMIDE DERIVATIVES AS HIV INHIBITORS
    Publication number: 20180237472
    Abstract: The invention relates to C-3 novel triterpenone with C-28 amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases (formula 1).
    Type: Application
    Filed: March 12, 2016
    Publication date: August 23, 2018
    Inventors: Parthasaradhi Reddy BANDI, Rathnakar Reddy KURA, David Krupadanam GAZULA LEVI, Panduranga Reddy ADULLA, Eswara Rao BAMMIDI, Bhaskar Reddy KASIREDDY, Sudhakar NEELA, Carl Thomas WILD, David Eugene MARTIN, Theodore John NITZ
  • Betulinic proline imidazole derivatives as HIV inhibitors
    Patent number: 9868758
    Abstract: The present invention relates to novel betulinic proline imidazole derivatives and related compounds, compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated diseases.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: January 16, 2018
    Assignee: HETERO LABS LIMITED
    Inventors: Parthasaradhi Reddy Bandi, Rathnakar Reddy Kura, Panduranga Reddy Adulla, David Krupadanam Gazula Levi, Eswara Rao Bammidi, Ranga Reddy, Carl Thomas Wild, David Eugene Martin, Theodore John Nitz
  • Preparation of Pharmaceutical Salts of 3-0-(3',3'-Dimethylsuccinyl) Betulinic Acid
    Publication number: 20110313191
    Abstract: This invention relates to a novel process for making 3-O-(3?,3?-dimethylsuccinyl)betulinic acid (“DSB”). This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.
    Type: Application
    Filed: July 5, 2011
    Publication date: December 22, 2011
    Applicant: Myrexis, Inc.
    Inventors: Christian Hemp, Arndt Hausherr, Theodore John Nitz, Roy Swaringen
  • 1,2,4-oxidiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
    Patent number: 5643929
    Abstract: Compounds of the formula ##STR1## wherein: R.sub.1 is alkyl, alkoxy, hydroxy, cycloalkyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkoxy, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxycarbonyl, carboxy, or cyanomethyl;Y is alkylene of 3 to 9 carbon atoms,R.sub.2 and R.sub.3 independently are hydrogen, alkyl, alkoxy, halo, cyano, trifluoromethyl and nitro;R.sub.4 is alkoxy, hydroxy, halomethyl, dihalomethyl, trihalomethyl, dihaloethyl, cycloalkyl, heterocyclyl, alkoxycarbonyl, hydroxyalkyl, alkoxyalkyl, alkanecarbonyloxyalkyl, cyano, halo, thioalkyl, alkylthioalkyl, alkylthio, thio, 2,2,2-trifluoro-ethyl, (4-methylphenyl)sulfonyloxymethyl, N=Q or CON=Q, where N=Q is amino, alkylamino or dialkylamino;R.sub.5 is hydrogen or halo or alkyl.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: July 1, 1997
    Assignee: Sanofi Winthrop, Inc.
    Inventors: Guy Dominic Diana, Theodore John Nitz