Patents by Inventor Theodore L. Iorio

Theodore L. Iorio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040198708
    Abstract: A pharmaceutical formulation is provided for pulmonary drug administration of a bronchodilator, a corticosteroid and an optional pharmaceutically acceptable carrier. In addition, methods for using the formulation to treat bronchodilator/corticosteroid-responsive conditions, diseases or disorders are provided, as are drug delivery devices and dosage forms for housing and/or dispensing the formulations.
    Type: Application
    Filed: April 14, 2004
    Publication date: October 7, 2004
    Inventors: Leonard W. Kaplan, Karl P. Weinrich, Theodore L. Iorio
  • Publication number: 20040185170
    Abstract: A method for coating drug-containing particles is provided comprising the steps of volatilizing a coating material and condensing the volatilized coating material onto a plurality of drug-containing particles. The method can be carried out without the use of solvents. Coated drug-containing particles as well as formulations and dosage forms containing coated particles are also described. A method for treating patients using drug-containing particles is provided as well.
    Type: Application
    Filed: March 21, 2003
    Publication date: September 23, 2004
    Inventors: Shubha Chungi, Theodore L. Iorio
  • Publication number: 20040043064
    Abstract: A pharmaceutical dosage form is provided. The dosage form is comprised of a capsule having a substantially moisture-impermeable outer surface, an enclosed interior cavity, and at least one active agent contained therein. The dosage form exhibits reduced moisture transmission. In addition, methods for reducing moisture transmission in a dosage form and methods of treating a patient are described.
    Type: Application
    Filed: August 29, 2002
    Publication date: March 4, 2004
    Inventors: Theodore L. Iorio, Shubha Chungi
  • Patent number: 6669955
    Abstract: An orally administrable pharmaceutical formulation is provided that combines, as active agents, a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, aspirin, and optionally at least one of vitamin B6, B12, and folate; the active agents are each present in a unit dose appropriate for once-daily dosing, and at least one of the active agents is contained in a dosage unit within the dosage form that physically separates it from the other active agents. The formulation is provided as a simple and convenient therapy to reduce the risk of cardiovascular events in individuals who are at elevated cardiovascular risk, including individuals who have systemic lupus erythematosus. The formulation is also therapeutic for individuals during or immediately following an occurrence of acute myocardial infarction.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: December 30, 2003
    Assignee: Longwood Pharmaceutical Research, Inc.
    Inventors: Shubha Chungi, Theodore L. Iorio
  • Publication number: 20030194439
    Abstract: Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second and optionally third dosage units, with each dosage unit having a different drug release profile. The dosage forms may comprise capsules housing compressed tablets or drug-containing beads or particles, or may comprise a single tablet with the first, second and optionally third dosage units each representing an integral and discrete segment thereof. Methods of treatment using the pharmaceutical dosage forms are provided as well.
    Type: Application
    Filed: April 28, 2003
    Publication date: October 16, 2003
    Inventors: Kamal K. Midha, Theodore L. Iorio, Shubha Chungi
  • Publication number: 20030068366
    Abstract: An orally administrable pharmaceutical formulation is provided that combines, as active agents, a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, aspirin, and optionally at least one of vitamin B6, B12, and folate; the active agents are each present in a unit dose appropriate for once-daily dosing, and at least one of the active agents is contained in a dosage unit within the dosage form that physically separates it from the other active agents. The formulation is provided as a simple and convenient therapy to reduce the risk of cardiovascular events in individuals who are at elevated cardiovascular risk, including individuals who have systemic lupus erythematosus. The formulation is also therapeutic for individuals during or immediately following an occurrence of acute myocardial infarction.
    Type: Application
    Filed: August 28, 2001
    Publication date: April 10, 2003
    Inventors: Shubha Chungi, Theodore L. Iorio
  • Publication number: 20020076382
    Abstract: A pharmaceutical formulation is provided for pulmonary drug administration of a bronchodilator, a corticosteroid and an optional pharmaceutically acceptable carrier. In addition, methods for using the formulation to treat bronchodilator/corticosteroid-responsive conditions, diseases or disorders are provided, as are drug delivery devices and dosage forms for housing and/or dispensing the formulations.
    Type: Application
    Filed: August 1, 2001
    Publication date: June 20, 2002
    Inventors: Leonard W. Kaplan, Karl P. Weinrich, Theodore L. Iorio
  • Publication number: 20020058061
    Abstract: Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second and optionally third dosage units, with each dosage unit having a different drug release profile. The dosage forms may comprise capsules housing compressed tablets or drug-containing beads or particles, or may comprise a single tablet with the first, second and optionally third dosage units each representing an integral and discrete segment thereof. Methods of treatment using the pharmaceutical dosage forms are provided as well.
    Type: Application
    Filed: November 13, 2001
    Publication date: May 16, 2002
    Inventors: Kamal K. Midha, Theodore L. Iorio, Shubha Chungi
  • Patent number: 6340476
    Abstract: Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second and optionally third dosage units, with each dosage unit having a different drug release profile. The dosage forms may comprise capsules housing compressed tablets or drug-containing beads or particles, or may comprise a single tablet with the first, second and optionally third dosage units each representing an integral and discrete segment thereof. Methods of treatment using the pharmaceutical dosage forms are provided as well.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: January 22, 2002
    Assignee: Armaquest, Inc.
    Inventors: Kamal K. Midha, Theodore L. Iorio, Shubha Chungi
  • Patent number: 4812303
    Abstract: The invention provides a tablet that will substantially dissolve rapidly in cool tap water or juice to yield a clear or almost clear calcium solution. The constituents of the tablet are calcium carbonate, fumaric acid and a water soluble third reactant wherein the calcium carbonate and the fumaric acid are present in approximately molar equivalent amounts and the third reactant is present in an amount sufficient to control the effervescence, allowing the tablet to dissolve completely without breaking apart and leaving any appreciable residue. The third reactant is preferably calcium lactate.
    Type: Grant
    Filed: April 3, 1986
    Date of Patent: March 14, 1989
    Assignee: Copley Pharmaceuticals, Inc.
    Inventor: Theodore L. Iorio