Abstract: Various implementations disclosed herein include devices, systems, and methods that provide customized feedback content during a meditation experience. For example, an example process may include obtaining physiological data via one or more sensors, determining that an attentive state based on the physiological data, customizing feedback content based on a user attribute to change the attentive state during the meditation mode, and providing the customized feedback content during the meditation mode after a delay time based on the user attribute.

Abstract: Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.

Abstract: Systems and methods can use subscription and identity authentication management to remove paywalls from websites. Login information for access to an application can be received from a user. The application can verify that the login information is associated with a subscriber account associated with a subscriber to the application. Instructions can be received to access a provider site from the user through the application. The application can determine that the provider site is associated with the subscriber account and the user; and then determine access credentials to the provider site based on a predetermined access scheme associated with the provider site. The access credentials can be injected into a paywall associated with the provider site.

Abstract: Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.

Abstract: Provided herein are methods and compositions for editing the genome of a human T cell. In some embodiments, a heterologous T cell receptor (TCR)-? chain and a heterologous TCR-? chain are inserted into exon 1 of a TCR subunit constant gene in the genome of the T cell.

Abstract: Systems and methods for updating software in a hazard detection system are described herein. Software updates may be received by, stored within, and executed by a hazard detection system, without disturbing the system's ability to monitor for alarm events and sound an alarm in response to a monitored hazard event. The software updates may be received as part of a periodic over-the-air communication with a remote server or as part of a physical connection with a data source such as a computer. The software updates may include several portions of code designed to operate with different processors and/or devices within the hazard detection system. The software updates may also include language specific audio files that can be accessed by the hazard detection system to play back language specific media files via a speaker.

Abstract: Provided herein are methods and compositions for identifying a targeted genomic insertion in a cell. Also provided are heterologous polypeptides that are co-expressed under the control of enodogenous loci and methods of using same.

Abstract: Provided herein are methods and compositions for editing the genome of a human T cell. In some embodiments, a heterologous T cell receptor (TCR)-? chain and a heterologous TCR-? chain are inserted into exon 1 of a TCR subunit constant gene in the genome of the T cell.

Abstract: Systems and methods of placeshifting media playback between two or more devices are provided. For example, a method for placeshifting media may include downloading onto a first device an index of files accessed or modified on a second device via a data storage server, at least one of the files being a media file played on the second device. The first device may display a user selectable list of the files on the first device before issuing a request for the media file to the data storage server. The data storage server may send the media file to the first device from the data storage server, and the first device may play back the media file where the second device left off.

Abstract: Disclosed is a method for predicting the future magnetic alignment of a runway. Extrapolating from previous historical records, the future trajectory of the Earth's eccentric geomagnetic axial pole (“ED”) is predicted. With that predicted trajectory as the basis, the future azimuthal change between the location of the ED and the location of an airfield is calculated. At the location of the airfield, a future change in the declination between true north and geomagnetic north is then calculated based on the predicted azimuthal change. The predicted change in declination then becomes the predicted change in magnetic alignment of any runway at the airfield. By predicting future changes in the magnetic alignment of a runway, preparations for changing the name of the runway can be made.

Abstract: Systems and methods of placeshifting media playback between two or more devices are provided. For example, a method for placeshifting media may include downloading onto a first device an index of files accessed or modified on a second device via a data storage server, at least one of the files being a media file played on the second device. The first device may display a user selectable list of the files on the first device before issuing a request for the media file to the data storage server. The data storage server may send the media file to the first device from the data storage server, and the first device may play back the media file where the second device left off.

Abstract: Provided herein are methods and compositions for editing the genome of a human T cell. In some embodiments, a heterologous T cell receptor (TCR)-? chain and a heterologous TCR-? chain are inserted into exon 1 of a TCR subunit constant gene in the genome of the T cell.

Abstract: Provided herein are methods and compositions for editing the genome of a human T cell. In some embodiments, a heterologous T cell receptor (TCR)-? chain and a heterologous TCR-? chain are inserted into exon 1 of a TCR subunit constant gene in the genome of the T cell.

Abstract: Examples described herein relate to apparatuses and methods for a computer simulation platform to solve a computer model, including splitting complex vectors generated for the computer model into real components and imaginary components by generating a first matrix corresponding to real components and a second matric corresponding to imaginary components, generating an appended matrix by appending the first matrix to the second matrix, generating a set of real, orthogonal vectors by running the appended matrix through a residual vector logic, and performing a real arithmetic-based computer simulation solution using the set of real, orthogonal vectors.

Abstract: Systems and methods for updating software in a hazard detection system are described herein. Software updates may be received by, stored within, and executed by a hazard detection system, without disturbing the system's ability to monitor for alarm events and sound an alarm in response to a monitored hazard event. The software updates may be received as part of a periodic over-the-air communication with a remote server or as part of a physical connection with a data source such as a computer. The software updates may include several portions of code designed to operate with different processors and/or devices within the hazard detection system. The software updates may also include language specific audio files that can be accessed by the hazard detection system to play back language specific media files via a speaker.

Abstract: Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.

Abstract: Systems and methods of placeshifting media playback between two or more devices are provided. For example, a method for placeshifting media may include downloading onto a first device an index of files accessed or modified on a second device via a data storage server, at least one of the files being a media file played on the second device. The first device may display a user selectable list of the files on the first device before issuing a request for the media file to the data storage server. The data storage server may send the media file to the first device from the data storage server, and the first device may play back the media file where the second device left off.

Abstract: The disclosure provides compositions and methods for modifying a target nucleic acid. In some embodiments, a composition can include a targetable nuclease, a DNA-binding protein, and a donor template comprising a homology directed repair (HDR) template and one or more DNA-binding protein target sequences. In some embodiments, a composition can include a Cas protein, one or more single guide RNAs (sgRNAs), and an anionic polymer.

Abstract: Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.