Patents by Inventor Theodore M. Bayless

Theodore M. Bayless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTING A POLYMORPHISM IN THE NFKB1 GENE PROMOTER
    Publication number: 20140249303
    Abstract: The present invention discloses a functional relationship between a recognized disease condition and a polymorphism in the nucleotide factor kappa B promoter (NFKB1). This relationship provides a platform for methods of altering promoter activity and for determining similar relationships between specific pathologies and identified polymorphisms. A statistically significant risk of developing ulcerative colitis was shown to be correlated with the presence of an ATTG insertion/deletion in the NFKB1 promoter and is likely to apply also to a variety of other inflammatory diseases.
    Type: Application
    Filed: October 4, 2013
    Publication date: September 4, 2014
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Steven R. Brant, Amir Karban, Franklin Nouvet, Theodore M. Bayless, James J. Potter, Esteban Mezey, Toshihiko Okazaki
  • METHODS FOR DETECTING A POLYMORPHISM IN THE NFKB1 GENE PROMOTER
    Publication number: 20120122761
    Abstract: The present invention discloses a functional relationship between a recognized disease condition and a polymorphism in the nucleotide factor kappa B promoter (NFKB1). This relationship provides a platform for methods of altering promoter activity and for determining similar relationships between specific pathologies and identified polymorphisms. A statistically significant risk of developing ulcerative colitis was shown to be correlated with the presence of an ATTG insertion/deletion in the NFKB1 promoter and is likely to apply also to a variety of other inflammatory diseases.
    Type: Application
    Filed: November 7, 2011
    Publication date: May 17, 2012
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Steven R. Brant, Amir Karban, Franklin Nouvet, Theodore M. Bayless, James J. Potter, Esteban Mezey, Toshihiko Okazaki
  • Methods for detecting a polymorphism in the NFKB1 gene promoter
    Patent number: 8071304
    Abstract: The present invention discloses a functional relationship between a recognized disease condition and a polymorphism in the nucleotide factor kappa B promoter (NFKB1). This relationship provides a platform for methods of altering promoter activity and for determining similar relationships between specific pathologies and identified polymorphisms. A statistically significant risk of developing ulcerative colitis was shown to be correlated with the presence of an ATTG insertion/deletion in the NFKB1 promoter and is likely to apply also to a variety of other inflammatory diseases.
    Type: Grant
    Filed: April 5, 2004
    Date of Patent: December 6, 2011
    Assignee: The Johns Hopkins University
    Inventors: Steven R. Brant, Amir Karban, Franklin Nouvet, Theodore M. Bayless, James J. Potter, Esteban Mezey, Toshihiko Okazaki