Patents by Inventor Theodore M. Tarasow

Theodore M. Tarasow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR USE WITH NANOREACTORS
    Publication number: 20100075436
    Abstract: The invention relates to methods of using nanoreactor technology for sample analysis in microfluidic systems.
    Type: Application
    Filed: May 6, 2009
    Publication date: March 25, 2010
    Inventors: Michael S. URDEA, Theodore M. TARASOW, Edward J. MOLER
  • Transition metal catalyzed cross-coupling of 1-halo-1-haloalkene compounds
    Publication number: 20090054667
    Abstract: Methods for introducing a 1-halo-1-haloalkene compound onto an aromatic or heteroaromatic ring are provided, including processes for the production of certain 1-halovinyl aryl or heteroaryl derivatives in which the 1-halovinyl group is either 1-fluoro or 1-chlorovinyl and the aromatic species phenyl or thiophene, the processes including coupling an arylmagnesium species with a dihalo olefin in the presence of a nickel or iron catalyst.
    Type: Application
    Filed: August 9, 2006
    Publication date: February 26, 2009
    Applicant: Replidyne, Inc.
    Inventors: Joseph W. Guiles, Jian Qiu, Theodore M. Tarasow
  • Transition Metal Catalyzed Cross-Coupling Of 1-Halo-1-Haloalkene Compounds
    Publication number: 20080194842
    Abstract: Methods for introducing a 1-halo-1-haloalkene compound onto an aromatic or heteroaromatic ring are provided, including processes for the production of certain 1-halovinyl aryl or heteroaryl derivatives in which the 1-halovinyl group is either 1-fluoro or 1-chlorovinyl and the aromatic species phenyl or thiophene, the processes including coupling an arylmagnesium species with a dihalo olefin in the presence of a nickel or iron catalyst.
    Type: Application
    Filed: August 9, 2006
    Publication date: August 14, 2008
    Applicant: REPLIDYNE, INC.
    Inventors: Joseph W. Guiles, Jian Qiu, Theodore M. Tarasow
  • Antibiotic compounds
    Patent number: 7179907
    Abstract: The present invention provides methods for identifying (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives with anti-PBP2a activity. The method involves the selection of RNA biocatalysts that promote the formation of (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives with anti-PBP2a activity from component reactants. The invention also provides novel (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives with anti-PBP2a activity identified by these methods. The invention also provides RNA biocatalysts that are capable of catalyzing the formation of (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives from component reactants.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: February 20, 2007
    Inventors: Bruce Eaton, Theodore M. Tarasow, Dan Nieuwlandt, Torin Dewey
  • Substituted thiophenes with antibacterial activity
    Patent number: 7030137
    Abstract: Novel substituted thiophenes that are inhibitors of bacterial methionyl t-RNA synthetase (MRS) are disclosed. Also disclosed are method for their preparation and their use in therapy as anti-bacterial agents.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: April 18, 2006
    Assignee: Replidyne, Inc.
    Inventors: John Berge, Richard Jarvest, Catherine Simone Victoire Frydrych, Joseph Guiles, Jian Qiu, Theodore M. Tarasow
  • Antibacterial methods and compositions
    Publication number: 20040224981
    Abstract: Disclosed is a pharmaceutical composition comprising an aminoacyl tRNA synthetase inhibitor and another antibacterial agent, including another aminoacyl tRNA synthetase inhibitor.
    Type: Application
    Filed: May 3, 2004
    Publication date: November 11, 2004
    Inventors: Nebojsa Janjic, Ian A. Critchley, Joseph Guiles, Theodore M. Tarasow
  • Parallel SELEX.TM.
    Patent number: 6048698
    Abstract: This invention discloses a method for coevolving products from two or more reactants, along with the nucleic acid that can facilitate the reaction for making the products. The invention further discloses the products and facilitating nucleic acids produced by said method.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: April 11, 2000
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Bruce Eaton, Theodore M. Tarasow