Patents by Inventor Theodore T. Puck

Theodore T. Puck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for distinguishing normal and cancer cells
    Patent number: 5264343
    Abstract: A method of electing the presence or absence of exposed nuclear DNA is described. Cells are reacted with a reaction composition comprising DNA polymerase I, DNase I, and the nucleotides dATP, dCTP, dGTP, and dTTP or dUTP, at least one of said nucleotides being biotin labeled. Biotin labeled nucleotides incorporated in exposed DNA are detected. Also described is a kit useful for detecting the presence or absence of exposed DNA in cells.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: November 23, 1993
    Assignee: Eleanor Roosevelt Institute
    Inventors: Alphonse Krystosek, Theodore T. Puck
  • Isolation and localization of DNA segments
    Patent number: 4594318
    Abstract: A process of isolating and identifying cloned DNA segments from defined regions of a chromosome by preparing a series of cell hybrids from a first species and a second species, which hybrids contain a chromosome or deletion mutant of a chromosome as the oThe Government has rights in this invention pursuant to Contract Number CA-5-14051 awarded by the Department of Health and Human Services, Contract Number PCM 77-17747 awarded by the National Science Foundation, and Contract Number 1-713 awarded by the National Foundation-March of Dimes.
    Type: Grant
    Filed: June 17, 1982
    Date of Patent: June 10, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: James F. Gusella, David Housman, Cheryl Keys, Aviva Varsanyi-Breiner, Theodore T. Puck, Carol Jones, Fa-Ten Kao