Patents by Inventor Theodoros Panagiotidis

Theodoros Panagiotidis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of O-desmethyl-venlafaxine and salts thereof
    Patent number: 8754261
    Abstract: The present invention relates to a novel process for the preparation of O-desmethyl venlafaxine (ODV) and the pharmaceutically acceptable salts thereof, wherein it comprises (i) provision of spiro-venlafaxine compound as intermediate; (ii) conversion of spiro-venlafaxine intermediate into ODV free base in a one-pot process; and (iii) optionally conversion ODV free base into pharmaceutically acceptable salts. The present invention further relates to novel processes for the preparation of crystalline salts of ODV-succinate and ODV-oxalate.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: June 17, 2014
    Assignee: Pharmathen S.A.
    Inventors: Theoharis V. Koftis, Ioanna Georgopoulou, Alexandros Strongilos, Fotini Liepouri, Theodoros Panagiotidis, Alexandra Lithadioti
  • PROCESS FOR THE PREPARATION OF O-DESMETHYL-VENLAFAXINE AND SALTS THEREOF
    Publication number: 20120253074
    Abstract: The present invention relates to a novel process for the preparation of O-desmethyl venlafaxine (ODV) and the pharmaceutically acceptable salts thereof, wherein it comprises (i) provision of spiro-venlafaxine compound as intermediate; (ii) conversion of spiro-venlafaxine intermediate into ODV free base in a one-pot process; and (iii) optionally conversion ODV free base into pharmaceutically acceptable salts. The present invention further relates to novel processes for the preparation of crystalline salts of OD V-succinate and ODV-oxalate.
    Type: Application
    Filed: December 16, 2009
    Publication date: October 4, 2012
    Applicant: PHARMATHEN S.A.
    Inventors: Theoharis V. Koftis, Ioanna Georgopoulou, Alexandros Strongilos, Fotini Liepouri, Theodoros Panagiotidis, Alexandra Lithadioti
  • PROCESS FOR THE PREPARATION OF PHENETHYLAMINE DERIVATIVES
    Publication number: 20100094055
    Abstract: The present invention relates to an improved process for the preparation of essentially pure Venlafaxine Hydrochloride. Particularly, the process for the preparation of Venlafaxine Hydrochloride comprises the following steps: i) Preparation of 1-[Cyano-1-(4-methoxyphenyl)methyl]cyclohexanol, ii) Preparation of crude Venlafaxine Hydrochloride by reduction of 1-[Cyano-1-(4-methoxyphenyl)methyl]cyclohexanol with Alkali metal borohydride and Lewis acid and subsequent conversion to Venalfaxine hydrochloride with formic acid and paraformaldehyde and finally iii) Purification of crude Venlafaxine Hydrochloride.
    Type: Application
    Filed: January 9, 2007
    Publication date: April 15, 2010
    Applicant: PHARMATHEN S.A.
    Inventors: Rohit Ravikant Soni, Theocharis Koftis, Theodoros Panagiotidis, Ioanna Georgopoulou