Patents by Inventor Theodorus Van Es

Theodorus Van Es has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-immunogenic polypeptides
    Patent number: 4179337
    Abstract: Polypeptides such as enzymes and insulin are coupled to polyethylene glycol or polypropropylene glycol having a molecular weight of 500 to 20,000 daltons to provide a physiologically active non-immunogenic water soluble polypeptide composition. The polyethylene glycol or polypropylene glycol protect the polypeptide from loss of activity and the composition can be injected into the mammalian circulatory system with substantially no immunogenic response.
    Type: Grant
    Filed: July 28, 1977
    Date of Patent: December 18, 1979
    Inventors: Frank F. Davis, Theodorus Van Es, Nicholas C. Palczuk