Patents by Inventor Theresa Hermel-Davidock
Theresa Hermel-Davidock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11649343Abstract: Components of medical devices include polypropylene-poly(ethylene oxide) amphiphilic graft copolymers (PP-g-PEO) in their base polymer formulations. The base polymeric formulations comprise at least a polymer or co-polymer of propylene. These components are suitable for solvent-bonding with other components and enhance bond strength of the medical devices.Type: GrantFiled: September 4, 2020Date of Patent: May 16, 2023Assignee: Becton, Dickinson and CompanyInventors: Jianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin, Tea Datashvili
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Patent number: 11649341Abstract: Components of medical devices include polyethylene-poly(ethylene oxide) amphiphilic graft copolymers (PE-g-PEO) in their base polymer formulations. The base polymeric formulations comprise at least a polymer or co-polymer of ethylene. These components are suitable for solvent-bonding with other components and enhance bond strength of the medical devices.Type: GrantFiled: September 4, 2020Date of Patent: May 16, 2023Assignee: Becton, Dickinson and CompanyInventors: Jianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin, Tea Datashvili
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Patent number: 11478573Abstract: Catheter tubing comprises: an elongate body comprising a base thermoplastic polyurethane; and a compounded thermoplastic polyurethane co-extruded with the base thermoplastic polyurethane to provide a section of catheter tubing discrete from the elongate body, the compounded thermoplastic polyurethane comprising a thermoplastic polyurethane and a radiopaque material, wherein the catheter tubing comprises a first elastic modulus under first conditions prior to entry into a patient; and wherein when exposed to second conditions comprising two or more in vivo stimuli for a duration of time the catheter tubing comprises a second elastic modulus that is not more than fifty percent of the first modulus.Type: GrantFiled: February 12, 2020Date of Patent: October 25, 2022Assignee: Becton, Dickinson and CompanyInventors: Lisa Lim, Theresa Hermel-Davidock, Marc W. Weimer, Jonathan Karl Burkholz
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Patent number: 11198801Abstract: Amphiphilic graft copolymers comprise a polypropylene backbone and hybrid micromolecule side-chains based on organo-functional silanes (PP-g-XSiOA) in the presence of a co-agent, for example, difunctional metallic diacrylate monomers, where “X” is an organic group or an organo-functional group, and “A” is a metal, an inorganic oxide, an inorganic hydroxide, or any other inorganic material. X may be derived from a compound selected from the group consisting of epoxy, amino, acrylate, methacryloxy, and vinyl; and A is selected from the group consisting of: silicon, (Si), aluminum (Al), iron (Fe), titanium (Ti), silver (Ag), zinc (Zn), nickel (Ni), calcium (Ca), copper (Cu), tin (Sn); oxides thereof; hydroxides thereof; and mixtures of the foregoing. These copolymers are suitable for forming medical devices and/or as additives to base polymeric formulations for medical devices for improving laser marking, antimicrobial resistance, adhesive free bond strength, paintability and dyeability.Type: GrantFiled: August 17, 2018Date of Patent: December 14, 2021Assignee: Becton, Dickinson and CompanyInventors: Theresa Hermel-Davidock, Tea Datashvili
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Patent number: 11111362Abstract: Films for medical devices and/or packaging include polyethylene-poly(ethylene oxide) amphiphilic graft copolymers (PE-g-PEO) in their base polymer formulations of polyethylene and poly(ethylene oxide). The films may be treated to include a nitric-oxide releasing agent incorporated into the PE-g-PEO. Also, microbial agents for inclusion in medical devices are provided, which comprise: an olefin-poly(ethylene oxide) amphiphilic graft copolymer, wherein a portion of the poly(ethylene oxide) comprises end groups converted to a nitric oxide-releasing agent. The amphiphilic graft copolymer of the microbial agents may comprise a polyethylene-poly(ethylene oxide) amphiphilic graft copolymer (PE-g-PEO), a polypropylene-poly(ethylene oxide) amphiphilic graft copolymer (PP-g-PEO), or mixtures thereof.Type: GrantFiled: September 21, 2017Date of Patent: September 7, 2021Assignee: Becton, Dickinson and CompanyInventors: Jianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin
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Patent number: 10995298Abstract: A polymer resin composition is disclosed including a chemically attached lubricant structure to produce a self-lubricating medical device thereby eliminating the need of a secondary lubrication step currently required which is useful in medical and surgical devices.Type: GrantFiled: July 22, 2015Date of Patent: May 4, 2021Assignee: Becton, Dickinson and CompanyInventors: Theresa Hermel-Davidock, Lisa Lim
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Patent number: 10995299Abstract: A polymer resin composition is disclosed including a chemically attached lubricant structure to produce a self-lubricating medical device thereby eliminating the need of a secondary lubrication step currently required which is useful in medical and surgical devices.Type: GrantFiled: April 23, 2018Date of Patent: May 4, 2021Assignee: Becton, Dickinson and CompanyInventors: Theresa Hermel-Davidock, Lisa Lim
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Patent number: 10995175Abstract: Principles and embodiments of the present invention relate generally to thermoplastic polyurethane materials having controlled and improved stiffness and/or flexibility, and methods to prepare them. The thermoplastic polyurethanes described herein having superior stiffness and softening properties may be fabricated into film, tubing, and other forms of medical devices. The thermoplastic polyurethanes comprise: an aromatic diisocyanate excluding non-aromatic diisocyanates; at least one polyglycol; and a chain extender comprising at least one side-chain branching diol and excluding linear diols.Type: GrantFiled: October 12, 2016Date of Patent: May 4, 2021Assignee: Becton, Dickinson and CompanyInventors: Ming Zhou, Theresa Hermel-Davidock
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Publication number: 20200399457Abstract: Components of medical devices include polypropylene-poly(ethylene oxide) amphiphilic graft copolymers (PP-g-PEO) in their base polymer formulations. The base polymeric formulations comprise at least a polymer or co-polymer of propylene. These components are suitable for solvent-bonding with other components and enhance bond strength of the medical devices.Type: ApplicationFiled: September 4, 2020Publication date: December 24, 2020Applicant: Becton, Dickinson and CompanyInventors: Jianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin, Tea Datashvili
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Publication number: 20200399453Abstract: Components of medical devices include polyethylene-poly(ethylene oxide) amphiphilic graft copolymers (PE-g-PEO) in their base polymer formulations. The base polymeric formulations comprise at least a polymer or co-polymer of ethylene. These components are suitable for solvent-bonding with other components and enhance bond strength of the medical devices.Type: ApplicationFiled: September 4, 2020Publication date: December 24, 2020Applicant: Becton, Dickinson and CompanyInventors: Jianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin, Tea Datashvili
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Patent number: 10814040Abstract: Medical devices comprise a polymeric body comprising: a base polymeric formulation comprising at least a polymer or co-polymer of propylene; and an additive comprising a copolymer having a polypropylene backbone and hybrid micromolecule side-chains based on organo-functional silanes (PP-g-XSiOA) in the presence of a co-agent, for example, difunctional metallic diacrylate monomers, where “X” is an organic group or an organo-functional group, and “A” is a metal, an inorganic oxide, an inorganic hydroxide, or any other inorganic material. X may be derived from a compound selected from the group consisting of epoxy, amino, acrylate, methacryloxy, and vinyl; and A is selected from the group consisting of: silicon, (Si), aluminum (Al), iron (Fe), titanium (Ti), silver (Ag), zinc (Zn), nickel (Ni), calcium (Ca), copper (Cu), tin (Sn); oxides thereof; hydroxides thereof; and mixtures of the foregoing. Optionally, inorganic fillers may be included. The medical devices are laser markable.Type: GrantFiled: August 17, 2018Date of Patent: October 27, 2020Assignee: Becton, Dickinson and CompanyInventors: Theresa Hermel-Davidock, Tea Datashvili
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Patent number: 10806829Abstract: Medical devices comprise a polymeric body comprising: a base polymeric formulation comprising at least a polymer or co-polymer of propylene; and an additive comprising a copolymer having a polypropylene backbone and hybrid micromolecule side-chains based on organo-functional silanes (PP-g-XSiOA) in the presence of a co-agent, for example, difunctional metallic diacrylate monomers, where “X” is an organic group or an organo-functional group, and “A” is a metal, an inorganic oxide, an inorganic hydroxide, or any other inorganic material. X may be derived from a compound selected from the group consisting of epoxy, amino, acrylate, methacryloxy, and vinyl; and A is selected from the group consisting of: silicon, (Si), aluminum (Al), iron (Fe), titanium (Ti), silver (Ag), zinc (Zn), nickel (Ni), calcium (Ca), copper (Cu), tin (Sn); oxides thereof; hydroxides thereof; and mixtures of the foregoing. Antimicrobial agents are included in the polymeric body. The medical devices have enhanced antimicrobial properties.Type: GrantFiled: August 17, 2018Date of Patent: October 20, 2020Assignee: Becton, Dickinson and CompanyInventors: Theresa Hermel-Davidock, Tea Datashvili
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Publication number: 20200179572Abstract: Catheter tubing comprises: an elongate body comprising a base thermoplastic polyurethane; and a compounded thermoplastic polyurethane co-extruded with the base thermoplastic polyurethane to provide a section of catheter tubing discrete from the elongate body, the compounded thermoplastic polyurethane comprising a thermoplastic polyurethane and a radiopaque material, wherein the catheter tubing comprises a first elastic modulus under first conditions prior to entry into a patient; and wherein when exposed to second conditions comprising two or more in vivo stimuli for a duration of time the catheter tubing comprises a second elastic modulus that is not more than fifty percent of the first modulus.Type: ApplicationFiled: February 12, 2020Publication date: June 11, 2020Inventors: Lisa Lim, Theresa Hermel-Davidock, Marc W. Weimer, Jonathan Karl Burkholz
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Patent number: 10654979Abstract: Amphiphilic graft copolymers comprise a polypropylene backbone and polyoxyalkylene side-chains (PPMA-g-PEO-PPO). These copolymers are suitable as additives to base polymeric formulations for medical devices for improving bond strength, paintability, dyeability, and printablity.Type: GrantFiled: August 8, 2018Date of Patent: May 19, 2020Assignee: Becton, Dickinson and CompanyInventors: Theresa Hermel-Davidock, Jianbin Zhang, Tea Datashvili
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Patent number: 10596302Abstract: Catheter tubing comprises: an elongate body comprising a base thermoplastic polyurethane; and a compounded thermoplastic polyurethane co-extruded with the base thermoplastic polyurethane to provide a section of catheter tubing discrete from the elongate body, the compounded thermoplastic polyurethane comprising a thermoplastic polyurethane and a radiopaque material, wherein the catheter tubing comprises a first elastic modulus under first conditions prior to entry into a patient; and wherein when exposed to second conditions comprising two or more in vivo stimuli for a duration of time the catheter tubing comprises a second elastic modulus that is not more than fifty percent of the first modulus.Type: GrantFiled: April 17, 2017Date of Patent: March 24, 2020Assignee: Becton, Dickinson and CompanyInventors: Lisa Lim, Theresa Hermel-Davidock, Marc W. Weimer, Jonathan Karl Burkholz
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Patent number: 10336852Abstract: A novel amphiphilic graft copolymer is described. A process to make amphiphilic graft copolymers via grafting either poly(ethylene oxide) or polylactide side chains onto an EVA platform using oxo-anion ring-opening polymerization chemistry is also described. Polyethylene or polypropylene based graft copolymers are prepared starting from poly(ethylene-co-vinyl acetate) or maleic anhydride grafted isotactic polypropylene respectively. The amphiphilic character will result from the incorporation of hydrophilic poly(ethylene oxide) (PEO) side-chains. Various applications of the novel amphiphilic graft copolymer are also described including, but not limited to, thermoplastic elastomer, films, fibers, fabrics, gels, breathable packaging materials, additive for biodegradable system, surfactant, antistatic additives, polymer compatibilizers, phase transfer catalysts, solid polymer electrolytes, biocompatible polymers, or incorporation into the materials listed above.Type: GrantFiled: April 11, 2017Date of Patent: July 2, 2019Assignees: Becton, Dickinson and Company, The University of MassachusettsInventors: Theresa Hermel-Davidock, Edward Bryan Coughlin
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Publication number: 20190175794Abstract: Medical devices configured to provide a controllable release of a drug, particularly for use in pleural effusion therapy. The medical devices comprise a component including a carrier-drug complex, wherein the carrier-drug complex comprises one or more molecules of a drug reversibly bound to a porous carrier. The present disclosure also relates to methods of making the carrier-drug complexes and medical devices described herein.Type: ApplicationFiled: December 11, 2017Publication date: June 13, 2019Inventors: Richard MENG, Theresa Hermel-Davidock, James Semler
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Publication number: 20190054214Abstract: Medical devices comprise a polymeric body comprising: a base polymeric formulation comprising at least a polymer or co-polymer of propylene; and an additive comprising a copolymer having a polypropylene backbone and hybrid micromolecule side-chains based on organo-functional silanes (PP-g-XSiOA) in the presence of a co-agent, for example, difunctional metallic diacrylate monomers, where “X” is an organic group or an organo-functional group, and “A” is a metal, an inorganic oxide, an inorganic hydroxide, or any other inorganic material. X may be derived from a compound selected from the group consisting of epoxy, amino, acrylate, methacryloxy, and vinyl; and A is selected from the group consisting of: silicon, (Si), aluminum (Al), iron (Fe), titanium (Ti), silver (Ag), zinc (Zn), nickel (Ni), calcium (Ca), copper (Cu), tin (Sn); oxides thereof; hydroxides thereof; and mixtures of the foregoing. Optionally, inorganic fillers may be included. The medical devices are laser markable.Type: ApplicationFiled: August 17, 2018Publication date: February 21, 2019Inventors: Theresa Hermel-Davidock, Tea Datashvili
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Publication number: 20190054213Abstract: Medical devices comprise a polymeric body comprising: a base polymeric formulation comprising at least a polymer or co-polymer of propylene; and an additive comprising a copolymer having a polypropylene backbone and hybrid micromolecule side-chains based on organo-functional silanes (PP-g-XSiOA) in the presence of a co-agent, for example, difunctional metallic diacrylate monomers, where “X” is an organic group or an organo-functional group, and “A” is a metal, an inorganic oxide, an inorganic hydroxide, or any other inorganic material. X may be derived from a compound selected from the group consisting of epoxy, amino, acrylate, methacryloxy, and vinyl; and A is selected from the group consisting of: silicon, (Si), aluminum (Al), iron (Fe), titanium (Ti), silver (Ag), zinc (Zn), nickel (Ni), calcium (Ca), copper (Cu), tin (Sn); oxides thereof; hydroxides thereof; and mixtures of the foregoing. Antimicrobial agents are included in the polymeric body. The medical devices have enhanced antimicrobial properties.Type: ApplicationFiled: August 17, 2018Publication date: February 21, 2019Inventors: Theresa Hermel-Davidock, Tea Datashvili
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Publication number: 20190055436Abstract: Amphiphilic graft copolymers comprise a polypropylene backbone and hybrid micromolecule side-chains based on organo-functional silanes (PP-g-XSiOA) in the presence of a co-agent, for example, difunctional metallic diacrylate monomers, where “X” is an organic group or an organo-functional group, and “A” is a metal, an inorganic oxide, an inorganic hydroxide, or any other inorganic material. X may be derived from a compound selected from the group consisting of epoxy, amino, acrylate, methacryloxy, and vinyl; and A is selected from the group consisting of: silicon, (Si), aluminum (Al), iron (Fe), titanium (Ti), silver (Ag), zinc (Zn), nickel (Ni), calcium (Ca), copper (Cu), tin (Sn); oxides thereof; hydroxides thereof; and mixtures of the foregoing. These copolymers are suitable for forming medical devices and/or as additives to base polymeric formulations for medical devices for improving laser marking, antimicrobial resistance, adhesive free bond strength, paintability and dyeability.Type: ApplicationFiled: August 17, 2018Publication date: February 21, 2019Inventors: Theresa Hermel-Davidock, Tea Datashvili