Patents by Inventor Theresa Johnson
Theresa Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240025922Abstract: Tetrahydropyrido[3,4-d]pyrimidines compounds are provided that are potent HPK1 inhibitors. The compounds are useful to treat or prevent cancer and/or inflammatory and/or autoimmune diseases or symptoms thereof in mammals, particularly humans. The compounds have a chemical structure of the general Formula (I), (II), (III), (IV) or (V) or enantiomers or diastereomers or mixtures thereof or pharmaceutically acceptable salts thereof.Type: ApplicationFiled: May 8, 2023Publication date: January 25, 2024Inventors: Momar TOURE, Bin LI, Constantin NEAGU, Yanping WANG, Theresa JOHNSON, Andrea UNZUE LOPEZ, Yufang XIAO, Emily FRIIS, Maria DIPOTO, Satenig GULER
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Patent number: 11873303Abstract: The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.Type: GrantFiled: April 1, 2019Date of Patent: January 16, 2024Assignee: Merck Patent GmbHInventors: Catherine Jorand-Lebrun, Nadia Brugger, Theresa Johnson
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Patent number: 11702392Abstract: The invention relates to pyrimidinone derivatives of the general Formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: GrantFiled: February 22, 2021Date of Patent: July 18, 2023Assignee: Merck Patent GmbHInventors: Catherine Jorand-Lebrun, Roch Boivin, Theresa Johnson, Yanping Wang, Yufang Xiao, Xiaoling Chen, Nina Linde, Doreen Musch, Deepak Kumar
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Patent number: 11696916Abstract: The invention relates to carboxamide-pyrimidine derivatives of the general formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: GrantFiled: April 30, 2021Date of Patent: July 11, 2023Assignee: Merck Patent GmbHInventors: Catherine Jorand-Lebrun, Roch Boivin, Igor Mochalkin, Theresa Johnson, Nina Linde, Doreen Musch, Deepak Kumar
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Patent number: 11564827Abstract: An ostomy output diversion device is used to cover and seal closely around a patient's stoma, to divert stoma effluent output through the device, through a drain tube and into a container or reservoir, temporarily eliminating the need of an adhesive-based ostomy pouching system. The ostomy output diversion device is placed over the person's stoma, with the base ring surrounding the peristomal skin, the adjustable inner tube is retracted until the base ring is centered over the stoma, the body support strap is then placed over the device to secure it to the patient's body, the inner tube with stoma-sized adapter is then extended over the stoma, the patient applies the desired pressure against the skin, then secures the stoma-sized adapter in place with the pressure adjustment lock. The device may also include an ostomy pouch mounting ring for attachment to an ostomy pouch, and a disposable receptacle.Type: GrantFiled: July 22, 2019Date of Patent: January 31, 2023Inventors: Bruce Johnson, Theresa Johnson, Reed Johnson
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Publication number: 20220362244Abstract: The invention relates to carboxamide-pyrimidine derivatives of the general formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: ApplicationFiled: April 30, 2021Publication date: November 17, 2022Inventors: Catherine JORAND-LEBRUN, Roch BOIVIN, Igor MOCHALKIN, Theresa JOHNSON, Nina LINDE, Doreen MUSCH, Deepak KUMAR
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Publication number: 20220225623Abstract: A commercially prepared dry sweet dough mix, and preparation method therefor, for use in making a batter to prepare of home baked cooked goods having a sweet flavor. The dry sweet dough mix includes a mixture of component ingredients such as flour, chemical leavening agent, non-fat dry milk solids, eggs, and a sweetening agent, which are disposed in a preparation bag. Once the component ingredients are combined and finished, they may be advantageously stored in the preparation bag at a wide range of temperatures. To be used, the dry sweet dough mix is hydrated and massaged into a batter while still in the preparation bag in two to five minutes. Once prepared in this manner, the batter does not need any kneading or fermentation steps and may be baked or cooked in a conventional manner into products such as pies, dumpling, tea cookies or teacakes.Type: ApplicationFiled: December 28, 2021Publication date: July 21, 2022Inventor: Theresa Johnson-Blount
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Publication number: 20210179565Abstract: The invention relates to pyrimidinone derivatives of the general Formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: ApplicationFiled: February 22, 2021Publication date: June 17, 2021Inventors: Catherine JORAND-LEBRUN, Roch BOIVIN, Theresa JOHNSON, Yanping WANG, Yufang XIAO, Xiaoling CHEN, Nina LINDE, Doreen MUSCH, Deepak KUMAR
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Patent number: 11033547Abstract: The invention relates to carboxamide-pyrimidine derivatives of the general formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: GrantFiled: March 9, 2020Date of Patent: June 15, 2021Assignee: Merck Patent GmbHInventors: Catherine Jorand-LeBrun, Roch Boivin, Igor Mochalkin, Theresa Johnson, Nina Linde, Doreen Musch, Deepak Kumar
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Publication number: 20210163487Abstract: The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.Type: ApplicationFiled: April 1, 2019Publication date: June 3, 2021Inventors: Catherine JORAND-LEBRUN, Nadia BRUGGER, Theresa JOHNSON
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Patent number: 11001561Abstract: The invention relates to pyrimidinone derivatives of the general Formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: GrantFiled: April 8, 2020Date of Patent: May 11, 2021Assignee: Merck Patent GmbHInventors: Catherine Jorand-Lebrun, Roch Boivin, Theresa Johnson, Yanping Wang, Yufang Xiao, Xiaoling Chen, Nina Linde, Doreen Musch, Deepak Kumar
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Publication number: 20210022912Abstract: An ostomy output diversion device is used to cover and seal closely around a patient's stoma, to divert stoma effluent output through the device, through a drain tube and into a container or reservoir, temporarily eliminating the need of an adhesive-based ostomy pouching system. The ostomy output diversion device is placed over the person's stoma, with the base ring surrounding the peristomal skin, the adjustable inner tube is retracted until the base ring is centered over the stoma, the body support strap is then placed over the device to secure it to the patient's body, the inner tube with stoma-sized adapter is then extended over the stoma, the patient applies the desired pressure against the skin, then secures the stoma-sized adapter in place with the pressure adjustment lock. The device may also include an ostomy pouch mounting ring for attachment to an ostomy pouch, and a disposable receptacle.Type: ApplicationFiled: July 22, 2019Publication date: January 28, 2021Inventors: Bruce Johnson, Theresa Johnson, Reed Johnson
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Publication number: 20200317622Abstract: The invention relates to pyrimidinone derivatives of the general Formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: ApplicationFiled: April 8, 2020Publication date: October 8, 2020Inventors: Catherine Jorand-Lebrun, Roch Boivin, Theresa Johnson, Yanping Wang, Yufang Xiao, Xiaoling Chen, Nina Linde, Doreen Musch, Deepak Kumar
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Publication number: 20200281926Abstract: The invention relates to carboxamide-pyrimidine derivatives of the general formula I, or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.Type: ApplicationFiled: March 9, 2020Publication date: September 10, 2020Inventors: Catherine JORAND-LEBRUN, Roch BOIVIN, Igor MOCHALKIN, Theresa JOHNSON, Nina LINDE, Doreen MUSCH, Deepak KUMAR
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Publication number: 20200046542Abstract: An ostomy pouch replacement device allows ostomates with a surgically created stoma to collect, contain and dispose of bodily fluids during hygienic maintenance. The device is customizable to each ostomate's unique stoma diameter and provides a disposable waste receptacle having a hollow absorbent section and a solid absorbent section for sanitary, discreet and odorless disposal of both urine and excrement. The disposable waste receptacle may include a super absorbent polymer powder that becomes a gel in the presence of liquid. The device preferably consists of a disposable waste receptacle that may be positioned over the stoma and includes an absorbent inner material for capturing waste, a cap or plug or sealing the device after use, and a collar stand with a heating element for pressing an adhesive wafer to the skin and for holding the assembled device in an upright position.Type: ApplicationFiled: October 22, 2019Publication date: February 13, 2020Inventors: Theresa Johnson, Reed Johnson, Bruce Johnson
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Patent number: 10478328Abstract: An ostomy pouch replacement device allows ostomates with a surgically created stoma to collect, contain and dispose of bodily fluids during hygienic maintenance. The device is customizable to each ostomate's unique stoma diameter and provides a disposable waste receptacle having a hollow absorbent section and a solid absorbent section for sanitary, discreet and odorless disposal of both urine and excrement. The disposable waste receptacle may include a super absorbent polymer powder that becomes a gel in the presence of liquid. The device preferably consists of a disposable waste receptacle that may be positioned over the stoma and includes an absorbent inner material for capturing waste, a cap or plug for scaling the device after use, and a collar stand for pressing an adhesive wafer to the skin and for holding the assembled device in an upright position.Type: GrantFiled: May 9, 2019Date of Patent: November 19, 2019Inventors: Liney Guidry, Theresa Johnson, Reed Johnson, Bruce Johnson
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Publication number: 20190262167Abstract: An ostomy pouch replacement device allows ostomates with a surgically created stoma to collect, contain and dispose of bodily fluids during hygienic maintenance. The device is customizable to each ostomate's unique stoma diameter and provides a disposable waste receptacle having a hollow absorbent section and a solid absorbent section for sanitary, discreet and odorless disposal of both urine and excrement. The disposable waste receptacle may include a super absorbent polymer powder that becomes a gel in the presence of liquid. The device preferably consists of a disposable waste receptacle that may be positioned over the stoma and includes an absorbent inner material for capturing waste, a cap or plug for scaling the device after use, and a collar stand for pressing an adhesive wafer to the skin and for holding the assembled device in an upright position.Type: ApplicationFiled: May 9, 2019Publication date: August 29, 2019Inventors: Liney Guidry, Theresa Johnson, Reed Johnson, Bruce Johnson
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Patent number: 10357394Abstract: An ostomy pouch replacement device allows ostomates with a surgically created stoma to collect, contain and dispose of bodily fluids during hygienic maintenance. The device is customizable to each ostomate's unique stoma diameter and provides a disposable waste receptacle having a hollow absorbent section and a solid absorbent section for sanitary, discreet and odorless disposal of both urine and excrement. The disposable waste receptacle may include a super absorbent polymer powder that becomes a gel in the presence of liquid. The device preferably consists of a disposable waste receptacle that may be positioned over the stoma and includes an absorbent inner material for capturing waste, a cap or plug for sealing the device after use, and a collar stand for pressing an adhesive wafer to the skin and for holding the assembled device in an upright position.Type: GrantFiled: October 5, 2017Date of Patent: July 23, 2019Inventors: Liney Guidry, Theresa Johnson, Reed Johnson, Bruce Johnson
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Patent number: 10130505Abstract: An ostomy pouch replacement device is provided to allow ostomates with a surgically created stoma to collect, contain and dispose of bodily fluids during frequent hygienic maintenance. The device is customizable to each ostomate's unique stoma diameter and provides a disposable waste receptacle designed to have a hollow absorbent section and a solid absorbent section for sanitary, discreet and odorless disposal of both urine and excrement. The device preferably consists of a disposable waste receptacle that may be positioned over the stoma and further includes an absorbent inner material for capturing any waste that may be discharged, a push cap for pressing the absorbent material to the stoma, a cap or plug for sealing the device after use, and a collar stand for pressing an adhesive wafer to the skin and for holding the assembled device in an upright position.Type: GrantFiled: December 7, 2015Date of Patent: November 20, 2018Inventors: Liney Guidry, Theresa Johnson, Reed Johnson, Bruce Johnson
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Publication number: 20180028347Abstract: An ostomy pouch replacement device allows ostomates with a surgically created stoma to collect, contain and dispose of bodily fluids during hygienic maintenance. The device is customizable to each ostomate's unique stoma diameter and provides a disposable waste receptacle having a hollow absorbent section and a solid absorbent section for sanitary, discreet and odorless disposal of both urine and excrement. The disposable waste receptacle may include a super absorbent polymer powder that becomes a gel in the presence of liquid. The device preferably consists of a disposable waste receptacle that may be positioned over the stoma and includes an absorbent inner material for capturing waste, a cap or plug for sealing the device after use, and a collar stand for pressing an adhesive wafer to the skin and for holding the assembled device in an upright position.Type: ApplicationFiled: October 5, 2017Publication date: February 1, 2018Inventors: Liney Guidry, Theresa Johnson, Reed Johnson