Patents by Inventor Theresa Kott

Theresa Kott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES SPECIFIC FOR ALPHA-1,6-CORE-FUCOSYLATED PSA AND FUCOSYLATED FRAGMENTS THEREOF
    Publication number: 20230340147
    Abstract: The present invention relates to an antibody or an antigen binding fragment thereof that specifically binds to ?-1,6-core-fucosylated prostate specific antigen (PSA) and partial sequences thereof comprising the ?-1,6-core-fucose residue. The antibodies and antigen binding fragments significantly discriminate between core-fucosylated PSA or core-fucosylated PSA partial sequences and other glycosylated PSA species and partial sequences thereof lacking the core-fucose residue, including aglycosylated PSA, as well as core-fucosylated glycan in other contexts. The present invention further relates to nucleic acid molecules encoding the light chain variable region or the heavy chain variable region of the antibody of the invention, as well as vectors comprising said nucleic acid molecules.
    Type: Application
    Filed: March 21, 2023
    Publication date: October 26, 2023
    Inventors: Magdalena Swiatek-de Lange, Joanna Siebenhaar, Carol Jones, Thomas Pritchett, Andrea Muranyi, Caroline Dorothea Hojer, Michael Gerg, Lars Hillringhaus, Gloria Tabares, Christian Roessler, Michael Schraeml, Shalini Singh, Theresa Kott
  • Measurement of nicotinamde N-methyl transferase in diagnosis of lung cancer
    Patent number: 7785821
    Abstract: The present invention relates to the assessment of lung cancer. It discloses the use of protein NNMT in the assessment of lung cancer. It also relates to a method for assessing lung cancer by measuring NNMT in vitro in a liquid sample derived from an individual. Measurement of NNMT can, e.g., be used in the early detection or in the follow-up of patients with lung cancer.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: August 31, 2010
    Assignee: Roche Diagnostics Operations Inc.
    Inventors: Wolfgang Rollinger, Marie Luise Hagmann, Johann Karl, Theresa Kott, Markus Roessler, Michael Tacke
  • USE OF NNMT AS A MARKER FOR LUNG CANCER
    Publication number: 20090263841
    Abstract: The present invention relates to the assessment of lung cancer. It discloses the use of protein NNMT in the assessment of lung cancer. It also relates to a method for assessing lung cancer by measuring NNMT in vitro in a liquid sample derived from an individual. Measurement of NNMT can, e.g., be used in the early detection or in the follow-up of patients with lung cancer.
    Type: Application
    Filed: January 30, 2009
    Publication date: October 22, 2009
    Inventors: Wolfgang Rollinger, Marie_Luise Hagmann, Johann Karl, Theresa Kott, Markus Roessler, Michael Tacke
  • Nicotinamide N-methyltransferase as a marker for colorectal cancer
    Patent number: 7205118
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: April 17, 2007
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Theresa Kott, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Nicotinamide N-methyltransferase as a marker for colorectal cancer
    Publication number: 20060003368
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: June 14, 2005
    Publication date: January 5, 2006
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Theresa Kott, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Reagents and solid phase components in specific binding assays free of advanced glycosylation endproducts
    Publication number: 20030073138
    Abstract: The present invention relates to the field of detection and measurement of advanced glycosylation endproducts (AGEs), in particular to methods of selection and/or quality control of a reagent or a coated solid phase component appropriate for AGE-assays. It also relates to a process for production of an AGE-free solid phase component, the solid phase component, and to the use of such solid phase component.
    Type: Application
    Filed: March 21, 2002
    Publication date: April 17, 2003
    Inventors: Rosemarie Kientsch-Engel, Andreas Gallusser, Werner Naser, Helmut Lill, Peter Stahl, Theresa Kott, Josef Maier