Patents by Inventor THERESA LAVALLEE

THERESA LAVALLEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO MOLECULARLY CHARACTERIZE CIRCULATING TUMOR CELLS
    Publication number: 20110256155
    Abstract: The invention relates to a rapid, sensitive method to obtain a gene expression profile from a target cell population in a blood sample. The target cells can be circulating tumor cells. Disclosed are methods and kits for obtaining such profiles.
    Type: Application
    Filed: April 18, 2011
    Publication date: October 20, 2011
    Applicant: MEDIMMUNE, LLC
    Inventors: Jiaqi Huang, Haifeng Bao, Philip Brohawn, Patricia Burke, Xiaoru Chen, Theresa Lavallee, Yihong Yao
  • ANTI-ANGIOGENIC ACTIVITY OF 2-METHOXYESTRADIOL ANALOGS IN COMBINATION WITH ANTI-CANCER AGENTS
    Publication number: 20100113404
    Abstract: The present invention relates generally to methods and compositions for treating diseases characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering antiangiogenic agents in combination with anti-cancer agents. More specifically, the present invention relates to methods and compositions for treating diseases characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering 2-methoxyestradiol analogs, in combination with anti-cancer agents.
    Type: Application
    Filed: October 31, 2008
    Publication date: May 6, 2010
    Inventors: THERESA LAVALLEE, WILLIAM E. FOGLER, CAROLYN F. SIDOR
  • Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents
    Publication number: 20070185069
    Abstract: The present invention relates generally to methods and compositions of treating disease characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering antiangiogenic agents in combination with chemotherapeutic agents. More specifically, the present invention relates to a methods and compositions of treating diseases characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering 2-methoxyestradiol, in combination with chemotherapeutic agents.
    Type: Application
    Filed: November 14, 2006
    Publication date: August 9, 2007
    Inventors: Stacy Plum, Steven Strawn, Theresa LaVallee, Carolyn Sidor, William Fogler, Anthony Treston
  • Estradiol derivatives
    Publication number: 20070135400
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering compounds of the general formula: wherein the variables are defined in the specification.
    Type: Application
    Filed: February 2, 2007
    Publication date: June 14, 2007
    Inventors: Gregory Agoston, Theresa LaVallee, Victor Pribluda, Jamshed Shah, Anthony Treston
  • Methods of treating disease states using antiangiogenic agents
    Publication number: 20070010505
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering compounds of the general formula: wherein the variables are defined in the specification.
    Type: Application
    Filed: September 12, 2006
    Publication date: January 11, 2007
    Inventors: Gregory Agoston, Theresa LaVallee, Victor Pribluda, Jamshed Shah, Anthony Treston
  • Antiangiogenic agents
    Publication number: 20070004689
    Abstract: Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae: wherein Ra is selected from —OCH3, —OCH2CH3 or —CCCH3; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, or >C(H)-dioxolane, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
    Type: Application
    Filed: July 19, 2006
    Publication date: January 4, 2007
    Inventors: Gregory Agoston, Jamshed Shah, Lita Suwandi, Theresa LaVallee, Anthony Treston
  • Compositions and methods comprising proteinase activated receptor antagonists
    Publication number: 20060063930
    Abstract: Compositions and methods comprising proteinase activated receptor antagonists are provided. More particularly, the present invention relates to the use of proteins, peptides and molecules that bind to proteinase activated receptor 2, and inhibit the processes associated with the activation of that receptor. More specifically, the present invention provides novel compositions and methods for the treatment of disorders and diseases such as those associated with abnormal cellular proliferation, angiogenesis, inflammation and cancer.
    Type: Application
    Filed: August 19, 2005
    Publication date: March 23, 2006
    Inventors: Gregory Agoston, Todd Hembrough, Theresa LaVallee, Jamshed Shah, Lita Suwandi, Anthony Treston
  • Antiangiogenic agents
    Publication number: 20050203075
    Abstract: Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae: wherein Ra is selected from —OCH3, —OCH2CH3 or —CCCH3; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
    Type: Application
    Filed: March 11, 2005
    Publication date: September 15, 2005
    Inventors: Gregory Agoston, Jamshed Shah, Lita Suwandi, Theresa LaVallee, Anthony Treston
  • Antiangiogenic agents
    Publication number: 20050192258
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in the specification.
    Type: Application
    Filed: April 29, 2005
    Publication date: September 1, 2005
    Inventors: Gregory Agoston, Jamshed Shah, Kimberly Hunsucker, Victor Pribluda, Theresa LaVallee, Shawn Green, Christopher Herbstritt, Xiaoguo Zhan, Anthony Treston
  • Antiangiogenic agents
    Publication number: 20050014737
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering compounds of the general formula: wherein the variables are defined in the specification.
    Type: Application
    Filed: May 28, 2004
    Publication date: January 20, 2005
    Inventors: Gregory Agoston, Theresa LaVallee, Victor Pribluda, Jamshed Shah, Anthony Treston