Patents by Inventor Theresa M. LaVallee

Theresa M. LaVallee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating disease states using antiangiogenic agents
    Patent number: 8158612
    Abstract: Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae: wherein Ra is selected from —OCH3, —OCH2CH3 or —CCCH3; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: April 17, 2012
    Assignee: EntreMed, Inc.
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Lita Suwandi, Theresa M. LaVallee, Anthony M. Treston
  • METHODS OF TREATING DISEASE STATES USING ANTIANGIOGENIC AGENTS
    Publication number: 20090105205
    Abstract: Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae: wherein Ra is selected from —OCH3, —OCH2CH3 or —CCCH3; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 23, 2009
    Applicant: ENTREMED, INC.
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Lita Suwandi, Theresa M. LaVallee, Anthony M. Treston
  • Antiangiogenic agents
    Patent number: 7498322
    Abstract: Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae: wherein Ra is selected from —OCH3, —OCH2CH3 or —CCCH3; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: March 3, 2009
    Assignee: EntreMed, Inc.
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Lita Suwandi, Theresa M. LaVallee, Anthony M. Treston
  • METHOD OF TREATING AMYLOIDOSIS MEDIATED DISEASES
    Publication number: 20080234243
    Abstract: The compounds of the present invention can be used to inhibit formation of beta-amyloid protein. The present invention provides methods of preventing, delaying onset of, or treating diseases or conditions characterized or mediated by amyloidosis. In particular, the present invention is useful for preventing, delaying onset of, and treating Alzheimer's disease and related diseases causing dementia.
    Type: Application
    Filed: January 31, 2008
    Publication date: September 25, 2008
    Inventors: Theresa M. LaVallee, Anthony M. Treston, Todd A. Hembrough
  • Estradiol derivatives and pharmaceutical compositions using same
    Patent number: 7371741
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering compounds of the general formula: wherein the variables are defined in the specification.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: May 13, 2008
    Assignee: EntreMed, Inc.
    Inventors: Gregory E. Agoston, Theresa M. LaVallee, Victor S. Pribluda, Jamshed H. Shah, Anthony M. Treston
  • Antiangiogenic agents
    Patent number: 7135581
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in the specification.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: November 14, 2006
    Assignee: Entremed, Inc.
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Kimberly A. Hunsucker, Victor S. Pribluda, Theresa M. LaVallee, Shawn J. Green, Christopher J. Herbstritt, Xiaoguo H. Zhan, Anthony M. Treston
  • Antiangiogenic agents
    Publication number: 20020082433
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: 1
    Type: Application
    Filed: August 24, 2001
    Publication date: June 27, 2002
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Kimberly A. Hunsucker, Victor S. Pribluda, Theresa M. LaVallee, Shawn J. Green, Christopher J. Herbstritt, Xiaoguo H. Zhan, Anthony M. Treston