Patents by Inventor Theresa Mawn

Theresa Mawn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo detection of phospholipase activation
    Patent number: 11034994
    Abstract: The present invention is directed to a phospholipid-based NIR molecular beacon, having a phospholipid moiety; with an NIR fluorophore moiety covalently linked to a phospholipid glycerol backbone and a quencher moiety covalently linked to the phospholipid glycerol backbone. Additionally, provided herein is methods of analyzing a sample for the presence of a phospholipase and methods of identifying the activity of a phospholipase in vivo utilizing phospholipid-based NIR molecular beacon.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: June 15, 2021
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Edward J. Delikatny, Anatoliy V. Popov, Gang Zheng, Theresa Mawn
  • IN VIVO DETECTION OF PHOSPHOLIPASE ACTIVATION
    Publication number: 20180245129
    Abstract: The present invention is directed to a phospholipid-based NIR molecular beacon, having a phospholipid moiety; with an NIR fluorophore moiety covalently linked to a phospholipid glycerol backbone and a quencher moiety covalently linked to the phospholipid glycerol backbone. Additionally, provided herein is methods of analyzing a sample for the presence of a phospholipase and methods of identifying the activity of a phospholipase in vivo utilizing phospholipid-based NIR molecular beacon.
    Type: Application
    Filed: April 30, 2018
    Publication date: August 30, 2018
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Edward J. DELIKATNY, Anatoliy V. Popov, Gang Zheng, Theresa Mawn
  • Vivo detection of phospholipase activation
    Patent number: 9957546
    Abstract: The present invention is directed to a phospholipid-based NIR molecular beacon, having a phospholipid moiety; with an NIR fluorophore moiety covalently linked to a phospholipid glycerol backbone and a quencher moiety covalently linked to the phospholipid glycerol backbone. Additionally, provided herein is methods of analyzing a sample for the presence of a phospholipase and methods of identifying the activity of a phospholipase in vivo utilizing phospholipid-based NIR molecular beacon.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: May 1, 2018
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: E. J. Delikatny, Anatoliy V. Popov, Gang Zheng, Theresa Mawn
  • VIVO DETECTION OF PHOSPHOLIPASE ACTIVATION
    Publication number: 20110165084
    Abstract: The present invention is directed to a phospholipid-based NIR molecular beacon, having a phospholipid moiety; with an NIR fluorophore moiety covalently linked to a phospholipid glycerol backbone and a quencher moiety covalently linked to the phospholipid glycerol backbone. Additionally, provided herein is methods of analyzing a sample for the presence of a phospholipase and methods of identifying the activity of a phospholipase in vivo utilizing phospholipid-based NIR molecular beacon.
    Type: Application
    Filed: March 3, 2009
    Publication date: July 7, 2011
    Inventors: E.J Delikatny, Anatoliy V. Popov, Gang Zheng, Theresa Mawn