Patents by Inventor Therese Graner

Therese Graner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220258130
    Abstract: The present invention relates to a novel chromatography media, more closely a novel IMAC (Immobilized Metal Affinity Chromatography) media. The novel chromatography media comprises a pentaligand and provides high dynamic binding capacity as well as high purity of the sample proteins purified on the media of the invention.
    Type: Application
    Filed: May 3, 2022
    Publication date: August 18, 2022
    Inventors: Ann Catharina Bergh, Mattias Algotsson, Tania Ahmad, Therese Graner
  • Patent number: 11124539
    Abstract: The present invention relates to the field of chromatography and more specifically to producing protein affinity chromatography resins comprising affinity ligands based on a N-terminal fragment of a split intein, such as DnaE from Nostoc punctiforme, as well as methods for using the same. The N-terminal fragments are produced in inclusion bodies in bacterial cells.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: September 21, 2021
    Assignee: Cytiva BioProcess R&D AB
    Inventors: Johan William Ohman, Mats Ander, Therese Graner, Anneli Jorsback, Jinyu Zou
  • Publication number: 20200023338
    Abstract: The present invention relates to a novel chromatography media, more closely a novel IMAC (Immobilized Metal Affinity Chromatography) media. The novel chromatography media comprises a pentaligand and provides high dynamic binding capacity as well as high purity of the sample proteins purified on the media of the invention.
    Type: Application
    Filed: September 27, 2017
    Publication date: January 23, 2020
    Applicant: GE Healthcare BioProcess R&D AB
    Inventors: Ann Catharina Bergh, Tania Ahmad, Mattias Algotsson, Therese Graner
  • Publication number: 20190263856
    Abstract: The present invention relates to the field of chromatography and more specifically to producing protein affinity chromatography resins comprising affinity ligands based on a N-terminal fragment of a split intein, such as DnaE from Nostoc punctiforme, as well as methods for using the same. The N-terminal fragments are produced in inclusion bodies in bacterial cells.
    Type: Application
    Filed: November 14, 2017
    Publication date: August 29, 2019
    Inventors: Johan Ohman, Mats Ander, Therese Graner, Anneli Jorsback, Jinyu Zou
  • Patent number: 9983203
    Abstract: Provided are methods for protein analysis in which proteins to be analyzed are displayed on a population of discrete and dispersible structures, such as beads or other particles, for subsequent affinity reactions and analysis/detection. The proteins to be analyzed may be provided as denatured protein samples in the presence of a denaturing agent.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: May 29, 2018
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Daniel Ivansson, Camilla Estmer Nilsson, Therese Graner, Johan Ohman
  • Publication number: 20160320377
    Abstract: The present invention relates to a method for protein analysis in which the proteins to be analyzed are displayed on a population of discrete and dispersible structures, such as beads or other particles, for subsequent affinity reactions and analysis/detection.
    Type: Application
    Filed: February 12, 2015
    Publication date: November 3, 2016
    Inventors: Daniel Ivannson, Camilla Estmer-Nilsson, Therese Graner, Johan Ohman
  • Patent number: 9433923
    Abstract: The present invention relates to a novel non-cross linked chromatography media provided with glutathione ligands which may or may not be provided with magnetic particles. The chromatography media is used for production of an affinity media provided with gluthatione ligands for adsorption of GST-tagged proteins.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: September 6, 2016
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Gunnar Glad, Therese Graner, Nils Norrman
  • Publication number: 20150151276
    Abstract: The present invention relates to a novel non-cross linked chromatography media provided with glutathione ligands which may or may not be provided with magnetic particles. The chromatography media is used for production of an affinity media provided with gluthatione ligands for adsorption of GST-tagged proteins.
    Type: Application
    Filed: June 11, 2013
    Publication date: June 4, 2015
    Inventors: Gunnar Glad, Therese Graner, Nils Norrman