Abstract: A microwave applicator for applying microwave radiation to body tissue includes a temperature sensor positioned along the applicator to measure the temperature of body tissue at a margin of the tissue to be treated. By monitoring the temperature of the tissue at the margin of the tissue to be treated, the heating of the tissue can be better controlled to ensure that the tissue to be treated is heated to the required temperature while damage to surrounding normal tissue is minimized. Treatment can include positioning one or more applicators into body tissue and applying microwave radiation to the applicators. Phase and amplitude control of the microwave radiation can be used to produce a desired heating pattern. Optimization of the number and location of microwave applicators and the phase and amplitude of microwave energy applied thereto can be determined through pretreatment simulation.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: An energy radiation applicator apparatus for hyperthermic treatment of targeted tissue in a patient is provided. The apparatus comprises a catheter for insertion into the patient, and an applicator operatively attached to the catheter and an energy source sufficient for elevating the temperature of targeted tissue in proximity to the applicator to a preselected temperature and for maintaining the preselected temperature during treatment. It may also comprise a positioning mechanism operatively attached to the catheter so that the applicator may be positioned at a desired position in proximity to the targeted tissue to be treated, a temperature sensor operatively attached to the catheter and in operative association with the applicator for measuring the temperature of the targeted tissue, and a locator for determining whether the applicator remains at the desired position.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: The present invention provides a method of treating a prostate in a patient in need thereof and a heating catheter, or an electromagnetic radiation applicator, system suitable for effecting the present inventive method. The present inventive method provides for substantial unexpected improvement in patient outcome by providing, inter alia, a preferred therapeutic temperature for thermotherapy of the prostate and a method of decreasing a patient's intolerance due to pain. The present inventive system provides for, inter alia, automatic implementation of the present inventive method.

Abstract: A method for the treatment of the prostate gland which heats the tissues which would otherwise be surgically removed with a trans-urethral resection of the prostate. This method is accomplished by combining a radiating energy device integrated with a urinary drainage Foley type catheter, which is modified to provide cooling along the urethra surfaces. The radiating device also serves as a means to measure the tissue radiated thermal energy for the control or monitoring of temperature of the prostate tissues being heated. A urethral inserted applicator for prostate hyperthermia includes a multi-tube, balloon type catheter. The catheter includes a fluid dry tube for an energy radiator antenna applicator which also serves as a radiometric temperature sensor for measuring the temperature of the prostate tissue, and an open fluid receiving tube. An electromagnetic energy generator supplies electromagnetic energy to the applicator.

Abstract: A urethral inserted applicator for prostate hyperthermia includes a multi-tube, balloon type catheter. The catheter includes first and second closed end fluid dry tubes, respectively, for a helical coil electrode type applicator, and an electromagnetic field compatible temperature sensor for measuring the temperature of the prostate tissue, and an open fluid receiving tube enabling urine drainage from the bladder. A radiofrequency source supplies electromagnetic energy to the applicator. A control unit contains a comparator which is connected to the temperature sensor and a temperature reference device for comparing the actual tissue temperature level with a desired temperature level and output control signals to the radiofrequency generator for controlling the output to the applicator. The coil type applicator is an elongated coil connected to the center conductor of a coaxial cable.

Abstract: A urethral inserted applicator for prostate hyperthermia includes a multi-tube, balloon type catheter. The catheter includes first and second closed end fluid dry tubes, respectively, for a helical coil antenna type applicator, and a microwave type temperature sensor for measuring the temperature of the prostate tissue, and an open fluid receiving tube. A microwave generator supplies electromagnetic energy to the applicator. A comparator is connected to the temperature sensor and a temperature reference potentiometer for comparing the actual tissue temperature level with a desired temperature level and outputting control signals to the microwave generator for controlling the output to the applicator. The coil type applicator is an elongated coil having a tip end connected to the center conductor of a coaxial cable and an opposite end connected to the outer conductor of the coaxial cable.