Abstract: A handheld cold plasma device in which the device includes power source, control electronic circuit boards connected to high-frequency high-voltage transformers, user control panels, insulating case covering control electronic circuits, high-frequency high-voltage transformer and user control panel to form a monoblock, the plasma generating unit contains the active electrode and the passive electrode outside the housing to allow the user to be connected to the neutral wires of the device. The device according to the present disclosure uses the principle of direct discharge (or dielectric barrier discharge with floating electrodes) with small size, inexpensive and does not use consumable materials.