Abstract: Solid-state platforms based on electro-nuclear spin systems are attractive candidates for rotation sensing due to their excellent sensitivity, stability, and compact size, compatible with industrial applications. Conventional spin-based gyroscopes measure the accumulated phase of a nuclear spin superposition state to extract the rotation rate and thus suffer from spin dephasing. A gyroscope protocol based on a two-spin system that includes a spin intrinsically tied to the host material, while the other spin is isolated. The rotation rate is then extracted by measuring the relative rotation angle between the two spins starting from their population states, robust against spin dephasing. In particular, the relative rotation rate between the two spins can be enhanced by their hyperfine coupling by more than an order of magnitude, further boosting the achievable sensitivity.

Abstract: An inflatable spa liner to be placed in a tub or spa pedicure bucket to prevent a user from contacting the surface of the tub is disclosed. The inflatable spa liner includes a first layer and a second layer that are sandwiched. The inflatable spa liner includes air channels formed at one of the first layer and the second layer. The air channels are arranged in between the first layer and the second layer. The inflatable spa liner is placed in a tub such that the first layer is in contact with the surface of the tub. The air channels inflate such that a user sitting in said inflatable spa liner contacting said second layer does not come in contact with the surface of said tub. A flexible tube is also sandwiched between the layers so that the air channels may be conveniently connected to an incoming air supply.

Abstract: In certain embodiments a light therapy system (e.g., phototherapy device), such as for treatment of Alzheimer's disease, depression, dementia, short-term memory, or for improved learning, improved athletic performance or improved cognitive performance, is provided where the light system comprises a blue light source that operates at a frequency in the range from 20 to 50 Hz (preferably around 40 Hz), whereby the system enables retinal ganglion cells of a human to be exposed in order to stimulate brain waves (gamma oscillations in the human's brain).

Abstract: A Peripheral Component Interconnect express (PCIe) Downstream Port Containment (DPC) System Management Interrupt (SMI) storm prevention system includes a Basic Input/Output System (BIOS) subsystem coupled to a first PCIe device. In response to an error being experienced in the first PCIe device and causing the first PCIe device to perform DPC operations, the BIOS subsystem receives a plurality of SMIs that are each configured to begin a System Management Mode (SMM). The BIOS subsystem tracks a number of the plurality of SMIs in a BIOS database and determines when the number of the plurality of SMIs has reached a DPC SMI storm threshold. In response to the number of the plurality of SMIs reaching the DPC SMI storm threshold, the BIOS subsystem prevents use of a link to the first PCIe device and prevents an operating system from performing recovery operations to recover the first PCIe device from the error.

Abstract: A Peripheral Component Interconnect express (PCIe) Downstream Port Containment (DPC) System Management Interrupt (SMI) storm prevention system includes a Basic Input/Output System (BIOS) subsystem coupled to a first PCIe device. In response to an error being experienced in the first PCIe device and causing the first PCIe device to perform DPC operations, the BIOS subsystem receives a plurality of SMIs that are each configured to begin a System Management Mode (SMM). The BIOS subsystem tracks a number of the plurality of SMIs in a BIOS database and determines when the number of the plurality of SMIs has reached a DPC SMI storm threshold. In response to the number of the plurality of SMIs reaching the DPC SMI storm threshold, the BIOS subsystem prevents use of a link to the first PCIe device and prevents an operating system from performing recovery operations to recover the first PCIe device from the error.

Abstract: A system may monitor usage of a cleaning chemical and indicate when the chemical has expired and needs to be replaced. In some examples, the system includes a reservoir containing the chemical and a sensor associated with the reservoir that can detect user interaction with the chemical in the reservoir. The system may track an amount of time until the chemical in the reservoir is deemed to have expired and provide a user alert indicating expiration of the chemical. The system can control the amount of time remaining until the chemical is deemed to have expired based on the detected addition of the object to the reservoir.

Abstract: An inflatable spa liner to be placed in a tub or spa pedicure bucket to prevent a user from contacting the surface of the tub is disclosed. The inflatable spa liner includes a first layer and a second layer that are sandwiched. The inflatable spa liner includes air channels formed at one of the first layer and the second layer. The air channels are arranged in between the first layer and the second layer. The inflatable spa liner is placed in a tub such that the first layer is in contact with the surface of the tub. The air channels inflate such that a user sitting in said inflatable spa liner contacting said second layer does not come in contact with the surface of said tub.

Abstract: In certain embodiments a light therapy system (e.g., phototherapy device), such as for treatment of Alzheimer's disease, depression, dementia, short-term memory, or for improved learning, improved athletic performance or improved cognitive performance, is provided where the light system comprises a blue light source that operates at a frequency in the range from 20 to 50 Hz (preferably around 40 Hz), whereby the system enables retinal ganglion cells of a human to be exposed in order to stimulate brain waves (gamma oscillations in the human's brain).

Abstract: A Peripheral Component Interconnect express (PCIe) Downstream Port Containment (DPC) System Management Interrupt (SMI) storm prevention system includes a Basic Input/Output System (BIOS) subsystem coupled to a first PCIe device. In response to an error being experienced in the first PCIe device and causing the first PCIe device to perform DPC operations, the BIOS subsystem receives a plurality of SMIs that are each configured to begin a System Management Mode (SMM). The BIOS subsystem tracks a number of the plurality of SMIs in a BIOS database and determines when the number of the plurality of SMIs has reached a DPC SMI storm threshold. In response to the number of the plurality of SMIs reaching the DPC SMI storm threshold, the BIOS subsystem prevents use of a link to the first PCIe device and prevents an operating system from performing recovery operations to recover the first PCIe device from the error.

Abstract: A PCIe device error handling system includes a BIOS subsystem coupled to a PCIe device and a BMC device. The BIOS subsystem identifies an error in the PCIe device and, in response, begins an SMM that suspends the performance of at least one workload in an operating system, and generates and transmits a PCIe device error information collection instruction associated with the PCIe device to the BMC device. Subsequent to transmitting the PCIe device error information collection instruction, the BIOS subsystem ends the SMM such that the performance of at least one workload is resumed in the operating system. In response to receiving the PCIe device error information collection instruction from the BIOS subsystem, the BMC device retrieves PCIe device error information from the PCIe device while the operating system performs the at least one workload, and stores the PCIe device error information.

Abstract: A method of operation of a compute system includes: receiving a patient image; segmenting a skin lesion in the patient image; constructing a normalized image by cropping the patient image and adding padding to position the skin lesion at the center of the normalized image; identifying, by a cancer artificial intelligence (AI) already trained, a skin cancer classification, a skin cancer sub-class, and a risk level assessment; and generating a skin cancer display including the normalized image, the skin cancer classification, the skin cancer sub-class, and the risk level assessment for displaying on a device.

Abstract: A system may monitor usage of a cleaning chemical and indicate when the chemical has expired and needs to be replaced. In some examples, the system includes a reservoir containing the chemical and a sensor associated with the reservoir that can detect user interaction with the chemical in the reservoir. The system may track an amount of time until the chemical in the reservoir is deemed to have expired and provide a user alert indicating expiration of the chemical. The system can control the amount of time remaining until the chemical is deemed to have expired based on the detected addition of the object to the reservoir.

Abstract: A method of operation of a compute system includes: detecting a skin area in a patient image; segmenting the skin area into a segmented image having an acne pimple at the center; generating a target pixel array from the segmented image includes separating a plurality of the acne pimples that are adjacent in the segmented image; identifying an acne characterization of the acne pimples including an area of each acne and an acne score; and assembling a user interface display from the acne characterization for displaying on a device.

Abstract: The present application provides materials and methods for treating hemoglobinopathies. More specifically, the application provides methods for producing progenitor cells that are genetically modified via genome editing to increase the production of fetal hemoglobin (HbF), as well as modified progenitor cells (including, for example, CD34+ human hematopoietic stem cells) producing increased levels of HbF, and methods of using such cells for treating hemoglobinopathies such as sickle cell anemia and ?-thalassemia.

Abstract: A pleated air filter media is provided. The pleated air filter media comprises a plurality of upstream linear bridging filaments that are extrusion-bonded to at least some of a plurality of upstream pleat tips of a fibrous web, and a plurality of downstream continuous-contact filaments that are extrusion-bonded to a downstream face of the fibrous web. Methods of making and using the same are also provided.

Abstract: Transistor cell architectures have three MO routing tracks within a single cell height. The cell architectures include at least one p-type transistor formed over a p-type diffusion region and at least one n-type transistor formed over an n-type diffusion region. Each diffusion region extends primarily in a particular direction, and the MO routing tracks extending in the same direction as the diffusion regions. One MO routing track may be formed over each of the diffusion regions, and a third MO routing track formed between the diffusion regions.

Abstract: The present application provides materials and methods for treating a patient with Alpha-1 antitrypsin deficiency (AATD) both ex vivo and in vivo. In addition, the present application provides materials and methods for editing the SERPINA1 gene in a cell by genome editing.

Abstract: An inflatable spa liner to be placed in a tub or spa pedicure bucket to prevent a user from contacting the surface of the tub is disclosed. The inflatable spa liner includes a first layer and a second layer that are sandwiched. The inflatable spa liner includes air channels formed at one of the first layer and the second layer. The air channels are arranged in between the first layer and the second layer. The inflatable spa liner is placed in a tub such that the first layer is in contact with the surface of the tub. The air channels inflate such that a user sitting in said inflatable spa liner contacting said second layer does not come in contact with the surface of said tub.

Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath with a tubular inner liner wound in a spiral configuration such that a plurality of protrusions is disposed in an overlapping portion of the sheath. The disclosed sheath is configured to expand from a predetermined rest diameter dr to an expanded diameter de during application of a radial outward force by passage of a medical device through the sheath.

Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath with a tubular inner liner wound in a spiral configuration at least a portion of the outer surface of the sheet comprises a plurality of bonding sites that are at least partially embedded within the sheet and disposed such that the outer surface of the sheet in the overlapping portion is substantially free of the plurality of bonding sites.