Patents by Inventor Thibaut Defever

Thibaut Defever has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9856526
    Abstract: A method and assembly for electrochemically identifying target nucleotide sequences. The method includes supplying a biological sample that may contain a predetermined target nucleotide sequence; supplying activatable amplification materials comprising free nucleotides to form replicated target nucleotide sequences; supplying an oxido-reducible compound capable of being inserted during replication between the nucleotides forming the replicated target sequences; and activating the activatable amplification materials before applying an electric field to the sample in order to activate the oxido-reducible compound. The replicated target sequences cause inhibition of electrochemical activity of the inserted oxido-reducible compound, and the presence of the predetermined target nucleotide sequence is determined in instances where the electric current decreases.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: January 2, 2018
    Assignees: UNIVERSITE PARIS DIDEROT-PARIS 7, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Benoît Limoges, Thibaut Defever, Damien Marchal
  • Publication number: 20150125870
    Abstract: A method and assembly for electrochemically identifying target nucleotide sequences. The method includes supplying a biological sample that may contain a predetermined target nucleotide sequence; supplying activatable amplification materials comprising free nucleotides to form replicated target nucleotide sequences; supplying an oxido-reducible compound capable of being inserted during replication between the nucleotides forming the replicated target sequences; and activating the activatable amplification materials before applying an electric field to the sample in order to activate the oxido-reducible compound. The replicated target sequences cause inhibition of electrochemical activity of the inserted oxido-reducible compound, and the presence of the predetermined target nucleotide sequence is determined in instances where the electric current decreases.
    Type: Application
    Filed: January 15, 2015
    Publication date: May 7, 2015
    Inventors: Benoît LIMOGES, Thibaut DEFEVER, Damien MARCHAL
  • Patent number: 8962240
    Abstract: A method and assembly for electrochemically identifying target nucleotide sequences. The method includes supplying a biological sample that may contain a predetermined target nucleotide sequence; supplying activatable amplification materials comprising free nucleotides to form replicated target nucleotide sequences; supplying an oxido-reducible compound capable of being inserted during replication between the nucleotides forming the replicated target sequences; and activating the activatable amplification materials before applying an electric field to the sample in order to activate the oxido-reducible compound. The replicated target sequences cause inhibition of electrochemical activity of the inserted oxido-reducible compound, and the presence of the predetermined target nucleotide sequence is determined in instances where the electric current decreases.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: February 24, 2015
    Assignees: Universite Paris Diderot-Paris 7, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Benoît Limoges, Thibaut Defever, Damien Marchal
  • Publication number: 20110136126
    Abstract: The present disclosure relates to a method and assembly for electrochemically identifying target nucleotide sequences. The method includes the following steps consisting of: supplying a biological sample that may contain a predetermined target nucleotide sequence; supplying activatable amplification means comprising free nucleotides in order to form replicated target nucleotide sequences; supplying an oxido-reducible compound capable of being inserted during replication between the nucleotides forming the replicated target sequences; and activating the activatable amplification means before applying an electric field to the sample in order to activate the oxido-reducible compound. Said replicated target sequences then cause the inhibition of the electrochemical activity of the inserted oxido-reducible compound, and the presence of the predetermined target nucleotide sequence is determined if the electric current decreases.
    Type: Application
    Filed: June 4, 2009
    Publication date: June 9, 2011
    Inventors: Benoît Limoges, Thibaut Defever, Damien Marchal