Abstract: A technology is described for generating placement and routing for a netlist of an integrated circuit (IC) design. The netlist for the IC design is partitioned into multiple subsets of cells. The subsets of cells are prioritized. Multiple stepwise place and route iterations are performed for the multiple subsets of cells. A first subset of cells with a first priority is placed in an arrangement representing the IC design. Wire connections are routed between the cells of the first subset of cells. A second subset of cells is placed relative to one another and the first subset of cells in the arrangement. Wire connections are routed between the cells of the second subset of cells and the cells of the first subset of cells.

Abstract: A technology is described for designing an integrated circuit (IC) by incrementally and concurrently synthesizing and formally verifying a plurality of intermediate netlists. The intermediate netlists are synthesized from a register transfer level (RTL) description of the IC. Synthesizing intermediate netlists is continued while the formal verification processes execute concurrently with the synthesizing. An indication of validity or non-validity of the intermediate netlists is from the formal verification process. The RTL description is proven to be formally equivalent to a final netlist formed of the intermediate netlists by proving that the all the intermediate netlists are valid.

Abstract: Technology is described for improvement of a Boolean Network. The method can include applying a plurality of transformation scripts to a Boolean Network to form a plurality of levels of a transformation tree with nodes representing transformation metrics for the transformation scripts applied to the Boolean Network. The nodes in individual levels of the transformation tree can be prioritized based in part on a cost function that uses the transformation metrics to identify an improved node as compared to less improved nodes in each of the plurality of levels of the transformation tree. Another operation may be identifying a transformation script using improved nodes of the transformation tree.

Abstract: The present invention relates to novel thiazolo[5,4-f]quinazoline compounds and methods that are useful in the amelioration, treatment or control of Down's syndrome or early Alzheimer's disease or in the amelioration, treatment or control of cancers, especially solid tumors. More specifically, the invention relates to DYRK1A and/or DYRK1B inhibitors and to methods for preparing such compounds.

Abstract: The present invention relates to novel thiazolo[5,4-f]quinazoline compounds and methods that are useful in the amelioration, treatment or control of Down's syndrome or early Alzheimer's disease or in the amelioration, treatment or control of cancers, especially solid tumors. More specifically, the invention relates to DYRK1A and/or DYRK1B inhibitors and to methods for preparing such compounds.