Patents by Inventor Thierry Bordet

Thierry Bordet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of cholest-4-en-3-one derivatives for obtaining a cytoprotective drug
    Patent number: 9320745
    Abstract: The present invention relates to the use of cholest-4-en-3-one derivatives for obtaining a cytoprotective drug, with the exception of a neuroprotective drug.
    Type: Grant
    Filed: March 28, 2007
    Date of Patent: April 26, 2016
    Assignee: TROPHOS
    Inventors: Rebecca Pruss, Bruno Buisson, Thierry Bordet
  • Derivatives of 3.5-seco-4-norcholestane and use thereof
    Patent number: 9045393
    Abstract: The invention relates to compounds of formula (I): where X+Y=keto, or X=OH and Y=H, or X+Y=oxime or methyloxime, B=OH and C+D=H, or C+D=C1-C4 linear or branched alkyl, or C=H and D=C1-C4 linear or branched alkyl, or B+C=keto and D=methyl, hydroxyl, or methylamino, or B and C=H and D=methylamino, or B+C=oxime and D=methyl and R=C1-C10 linear or branched alkyl, the salts, esters, or salts of esters thereof as medicament, in particular as neuroprotectors, novel compounds of formula (I) and pharmaceutical compositions.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: June 2, 2015
    Assignee: TROPHOS
    Inventors: Thierry Bordet, Cyrille Drouot
  • Method for providing neuroprotection
    Patent number: 8575138
    Abstract: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ?N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: November 5, 2013
    Assignee: Trophos
    Inventors: Thierry Bordet, Cyrille Drouot, Bruno Buisson
  • Method for providing neuroprotection from spinal muscular atrophy
    Patent number: 8354395
    Abstract: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ?N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: January 15, 2013
    Assignee: Trophos
    Inventors: Thierry Bordet, Cyrille Drouot, Bruno Buisson
  • METHOD FOR PROVIDING NEUROPROTECTION FROM SPINAL MUSCULAR ATROPHY
    Publication number: 20120316141
    Abstract: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ?N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: TROPHOS
    Inventors: Thierry BORDET, Cyrille DROUOT, Bruno BUISSON
  • METHOD FOR PROVIDING NEUROPROTECTION
    Publication number: 20120309721
    Abstract: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an =N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 6, 2012
    Applicant: TROPHOS
    Inventors: Thierry Bordet, Cyrille Drouot, Bruno Buisson
  • Use as medicaments of derivatives of cholest-4-en-3-one, pharmaceutical compositions containing them, novel derivatives and their preparation process
    Patent number: 8283341
    Abstract: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ?N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: October 9, 2012
    Assignee: Trophos
    Inventors: Thierry Bordet, Cyrille Drouot, Bruno Buisson
  • Use of 3,5-seco-4-nor-cholestane derivatives for obtaining a cytoprotective drug
    Patent number: 7985774
    Abstract: The present invention relates to the use of 3,5-seco-4-nor-cholestane derivatives for obtaining a cytoprotective drug, with the exception of a neuroprotective drug, notably a cardioprotective or hepatoprotective drug.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: July 26, 2011
    Assignee: Trophos
    Inventors: Rebecca Pruss, Bruno Buisson, Thierry Bordet
  • Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof
    Patent number: 7858603
    Abstract: Compound of formula I where X=O or ?N—OH group, R represents a group chosen from A=hydrogen or together with B a carbon-carbon bond, B=hydrogen, hydroxy or together with A a carbon-carbon bond, C, D, E, F=hydrogen or together with D a carbon-carbon bond, or the one of its addition salts with pharmaceutically acceptable acids, with the exception of a few compounds, as a medicament, use in particular as neuroprotectors, novel compounds of formula I and pharmaceutical compositions.
    Type: Grant
    Filed: March 5, 2004
    Date of Patent: December 28, 2010
    Assignee: TROPHOS
    Inventors: Thierry Bordet, Cyrille Drouot, Bruno Buisson
  • NOVEL COMPOSITION FOR TREATING THE SIDE EFFECTS OF ANTICANCER TREATMENTS
    Publication number: 20100310674
    Abstract: The invention relates to novel compositions, particularly pharmaceutical, comprising, as active ingredients, at least one cytotoxic agent and at least one cholest-4-en-3-one oxime derivative.
    Type: Application
    Filed: October 30, 2008
    Publication date: December 9, 2010
    Applicant: TROPHOS
    Inventors: Rebecca Pruss, Thierry Bordet, Jean-Louis Abitbol, Antoine Beret
  • USE AS MEDICAMENTS OF DERIVATIVES OF CHOLEST-4-EN-3-ONE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, NOVEL DERIVATIVES AND THEIR PREPARATION PROCESS
    Publication number: 20100216752
    Abstract: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ?N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
    Type: Application
    Filed: May 7, 2010
    Publication date: August 26, 2010
    Applicant: TROPHOS
    Inventors: Thierry BORDET, Cyrille Drouot, Bruno Buisson
  • USE OF 3,5-SECO-4-NOR-CHOLESTANE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE DRUG
    Publication number: 20090312434
    Abstract: The present invention relates to the use of 3,5-seco-4-nor-cholestane derivatives for obtaining a cytoprotective drug, with the exception of a neuroprotective drug, notably a cardioprotective or hepatoprotective drug.
    Type: Application
    Filed: February 23, 2007
    Publication date: December 17, 2009
    Applicant: TROPHOS
    Inventors: Rebecca Pruss, Bruno Buisson, Thierry Bordet
  • USE OF CHOLEST-4-EN-3-ONE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE DRUG
    Publication number: 20090186863
    Abstract: The present invention relates to the use of cholest-4-en-3-one derivatives for obtaining a cytoprotective drug, with the exception of a neuroprotective drug.
    Type: Application
    Filed: March 28, 2007
    Publication date: July 23, 2009
    Applicant: TROPHOS
    Inventors: Rebecca Pruss, Bruno Buisson, Thierry Bordet
  • Novel Derivatives of 3.5-Seco-4-Norcholestane and Use Thereof
    Publication number: 20080275130
    Abstract: The invention relates to compounds of formula (I): where X+Y=keto, or X=OH and Y=H, or X+Y=oxime or methyloxime, B=OH and C+D=H, or C+D=C1-C4 linear or branched alkyl, or C=H and D=C1-C4 linear or branched alkyl, or B+C=keto and D=methyl, hydroxyl, or methylamino, or B and C=H and D=methylamino, or B+C=oxime and D=methyl and R=C1-C10 linear or branched alkyl, the salts, esters, or salts of esters thereof as medicament, in particular as neuroprotectors, novel compounds of formula (I) and pharmaceutical compositions.
    Type: Application
    Filed: August 19, 2005
    Publication date: November 6, 2008
    Inventors: Thierry Bordet, Cyrille Drouot
  • Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof
    Publication number: 20060217358
    Abstract: Compound of formula I where X=O or ?N—OH group, R represents a group chosen from A=hydrogen or together with B a carbon-carbon bond, B=hydrogen, hydroxy or together with A a carbon-carbon bond, C, D, E, F=hydrogen or together with D a carbon-carbon bond, or the one of its addition salts with pharmaceutically acceptable acids, with the exception of a few compounds, as a medicament, use in particular as neuroprotectors, novel compounds of formula I and pharmaceutical compositions.
    Type: Application
    Filed: March 5, 2004
    Publication date: September 28, 2006
    Applicant: TROPHOS
    Inventors: Thierry Bordet, Cyrille Drouot, Bruno Buisson