Patents by Inventor Thierry Convard

Thierry Convard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
    Patent number: 9353100
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, and pharmaceutical compositions and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: May 31, 2016
    Assignee: Idenix Pharmaceuticals LLC
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Thierry Convard, Dominique Surleraux
  • Macrocyclic serine protease inhibitors
    Patent number: 9284307
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: March 15, 2016
    Assignee: Idenix Pharmaceuticals LLC
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Frederic Leroy, Thierry Convard, Dominique Surleraux
  • 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors
    Patent number: 9187496
    Abstract: Provided herein are 5,5-fused heteroarylene hepatitis C virus inhibitor compounds, for example, of Formula I, IA, or IB, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: November 17, 2015
    Assignee: Idenix Pharmaceuticals LLC
    Inventors: Cyril B. Dousson, David Dukhan, Christophe Claude Parsy, Claire Pierra, Francois-Rene Alexandre, Guillaume Brandt, Daniel Da Costa, Houcine Rahali, Jean-Laurent Paparin, Michel Derock, Thierry Convard, Dominique Surleraux
  • Macrocyclic serine protease inhibitors
    Patent number: 8993595
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: March 31, 2015
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Michel Derock, Frederic Leroy, Jean-Christophe Meillon, Thierry Convard, Dominique Surleraux
  • Macrocyclic serine protease inhibitors
    Patent number: 8377962
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: April 7, 2010
    Date of Patent: February 19, 2013
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Michel Derock, Frederic Leroy, Jean-Christophe Meillon, Thierry Convard, Dominique Surleraux
  • 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors
    Patent number: 8362068
    Abstract: Provided herein are 5,5-fused heteroarylene hepatitis C virus inhibitor compounds, for example, of Formula I, IA, or IB, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: January 29, 2013
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril B. Dousson, David Dukhan, Christophe Claude Parsy, Claire Pierra, Francois-Rene Alexandre, Guillaume Brandt, Daniel Da Costa, Houcine Rahali, Jean-Laurent Paparin, Michel Derock, Thierry Convard, Dominique Surleraux
  • Specific caspase-10 inhibitors
    Patent number: 8357721
    Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: January 22, 2013
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Thierry Convard, Catherine Vidal
  • METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR
    Publication number: 20120252721
    Abstract: Provided herein are methods for treating or preventing drug-resistant hepatitis C virus infection in a subject, which comprises administering to the subject a 5,5-fused heteroarylene hepatitis C virus inhibitor compound, for example, of Formula I, IA, or IB.
    Type: Application
    Filed: March 29, 2012
    Publication date: October 4, 2012
    Applicant: IDENIX PHARMACEUTICALS, INC.
    Inventors: Cyril B. Dousson, David Dukhan, John P. Billelo, Christophe Claude Parsy, Claire Pierra, Francois-Rene Alexandre, Guillaume Brandt, Daniel Da Costa, Houcine Rahali, Jean-Laurent Paparin, Michel Derock, Thierry Convard, Dominique Surleraux
  • MACROCYCLIC SERINE PROTEASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING HCV INFECTIONS
    Publication number: 20120207703
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, and pharmaceutical compositions and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: February 9, 2012
    Publication date: August 16, 2012
    Applicant: IDENIX PHARMACEUTICALS, INC.
    Inventors: Christophe Claude PARSY, Francois-Rene ALEXANDRE, Thierry CONVARD, Dominique SURLERAUX
  • 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS
    Publication number: 20110150827
    Abstract: Provided herein are 5,5-fused heteroarylene hepatitis C virus inhibitor compounds, for example, of Formula I, IA, or IB, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: December 17, 2010
    Publication date: June 23, 2011
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril B. Dousson, David Dukhan, Christophe Claude Parsy, Claire Pierra, Francois-Rene Alexandre, Guillaume Brandt, Daniel Da Costa, Houcine Rahali, Jean-Laurent Paparin, Michel Derock, Thierry Convard, Dominique Surleraux
  • MACROCYCLIC SERINE PROTEASE INHIBITORS
    Publication number: 20110129443
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: August 4, 2010
    Publication date: June 2, 2011
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Frederic Leroy, Thierry Convard, Dominique Surleraux
  • Specific caspase-10 inhibitors
    Patent number: 7829721
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: November 9, 2010
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stéphane Yvon, Marie Noelle Denuault, Denis Descours
  • MACROCYCLIC SERINE PROTEASE INHIBITORS
    Publication number: 20100260710
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: April 7, 2010
    Publication date: October 14, 2010
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Michel Derock, Frederic Leroy, Jean-Christophe Meillon, Thierry Convard, Dominique Surleraux
  • Thiazolylimidazole derivatives and their use as inhibitors of microsomal triglyceride transfer protein
    Patent number: 7767819
    Abstract: The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Grant
    Filed: January 17, 2005
    Date of Patent: August 3, 2010
    Assignee: Merck Patent GmbH
    Inventors: Philippe Guedat, Olivier Chevreuil, Thierry Convard
  • THIAZOLYLIMIDAZOLE DERIVATIVES AN THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN
    Publication number: 20100137601
    Abstract: The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Application
    Filed: February 4, 2010
    Publication date: June 3, 2010
    Inventors: Philippe GUEDAT, Olivier Chevreuil, Thierry Convard
  • Novel Specific Caspase-10 Inhibitors
    Publication number: 20080255173
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: November 2, 2005
    Publication date: October 16, 2008
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stephane Yvon, Marie Noelle Denuault, Denis Descours
  • Thiazolylimidazole Derivatives and Their Use as Inhibitors of Microsmal Triglyceride Transfer Protein
    Publication number: 20080214610
    Abstract: The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R1, R2, R3, R4, R5, R6, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
    Type: Application
    Filed: January 17, 2005
    Publication date: September 4, 2008
    Inventors: Philippe Guedat, Olivier Chevreuil, Thierry Convard
  • Novel Specific Caspase-10 Inhibitors
    Publication number: 20080182906
    Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: April 6, 2006
    Publication date: July 31, 2008
    Inventors: Claude Lardy, Marc Lecomte, Thierry Convard, Catherine Vidal
  • Seven-membered ring nucleosides
    Publication number: 20070185063
    Abstract: The present invention provides nucleoside analogue compounds that treat a host infected with a Flaviviridae virus infection, or other viruses that exhibit RNA-dependent RNA viral replication, compositions comprising these compounds and methods of using the compounds for the treatment and/or prophylaxis of viral infection, especially hepatitis C, in an infected host.
    Type: Application
    Filed: August 23, 2006
    Publication date: August 9, 2007
    Inventors: Richard Storer, Gilles Gosselin, David Dukhan, Frederic Leroy, Jean-Christophe Meillon, Thierry Convard
  • Computational data processing system and computational process implemented by means of such a system
    Patent number: 7159012
    Abstract: This computational data processing system comprises an assembly of networked computers (12, . . . 22) in each of which is stored at least one computational application, and a machine (10) for storing computational data which is linked to the network and in communication with the computers, at least one of the computers (12) operating as master computer and at least some of the other computers (14, . . . 22) operating as slave computer. At least one of the computers comprises, stored in memory an algorithm for configuring the other computers of the network as slave computers and an executable master application for managing the tasks of each slave computer (14, . . . 22) as a function of their availability for the assignment, to each of them, of computational tasks and of corresponding computational data which are stored in the storage machine (10).
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: January 2, 2007
    Assignee: LIPHA
    Inventors: Edouard Viollet, Thierry Convard, Jacques Barbanton