Abstract: An optical fiber has two or more core regions disposed within a common cladding region. Each of the core regions is configured to guide a respective light transmission comprising at least one optical mode along the length of the fiber. The cores are arranged within the common cladding region according to a core configuration that substantially prevents crosstalk between modes of neighboring cores in the fiber, in a deployment of the fiber in which cross-coupling between neighboring cores is affected by perturbations arising in the deployed fiber.

Abstract: A multicore optical fiber includes a plurality of core regions disposed within a common cladding region. Each of the plurality of core regions is configured, in combination with the common cladding region, to propagate light along a longitudinal axis of the fiber. At least two core regions are configured to inhibit resonant coupling of propagated light therebetween within a selected region of operation. At least one segment of the fiber includes a twist that is configured such that when the twisted segment is subjected to a bend having a selected radius, the twist creates a controlled change in the amount of crosstalk between the at least two core regions, compared with the amount of crosstalk between the at least two core regions when a bend having the selected radius is introduced into a non-twisted segment of the fiber.

Abstract: An optical fiber has two or more core regions disposed within a common cladding region. Each of the core regions is configured to guide a respective light transmission comprising at least one optical mode along the length of the fiber. The cores are arranged within the common cladding region according to a core configuration that substantially prevents crosstalk between modes of neighboring cores in the fiber, in a deployment of the fiber in which cross-coupling between neighboring cores is affected by perturbations arising in the deployed fiber.

Abstract: The present invention is related to accurate detection methods for the measurement only of myeloperoxidase (MPO) levels or neutrophils, preferably equine neutrophils, in complex biological samples. The present invention is further related to ELISA and SIEFED assays for such detection. SIEFED detection sensitivity of active peroxidase activity was found to be enhanced by the addition of nitrite. Such MPO measurement finds its use in many applications such as the prediction, diagnosis and/or monitoring of pathologies correlated with neutrophil activation and/or destruction; the evaluation of drugs and/or immunomodulators; the assessment of immune responses, either natural and/or after treatment with immunomodulators and/or drugs; and the study of cells and their ability to fight microorganisms and/or to destroy them.

Abstract: A multicore optical fiber includes a plurality of core regions disposed within a common cladding region. Each of the plurality of core regions is configured, in combination with the common cladding region, to propagate light along a longitudinal axis of the fiber. At least two core regions are configured to inhibit resonant coupling of propagated light therebetween within a selected region of operation. At least one segment of the fiber includes a twist that is configured such that when the twisted segment is subjected to a bend having a selected radius, the twist creates a controlled change in the amount of crosstalk between the at least two core regions, compared with the amount of crosstalk between the at least two core regions when a bend having the selected radius is introduced into a non-twisted segment of the fiber.

Abstract: The present invention is related to a combined method and kit (or device) for the sequential measurement of the enzymatically active fraction and the total amount of an enzyme [(such as myeloperoxidase (MPO)] in a sample, and that find improved applications in veterinary and human health fields.

Abstract: The present invention is related to accurate detection methods for the measurement only of myelopexidase (MPO) levels or neutrophils, preferably equine neutrophils, in complex biological samples. The present invention is further related to ELISA and SIEFED assays for such detection. SIEFED detection sensitivity of active peroxidase activity was found to be enhanced by the addition of nitrite. Such MPO measurement finds its use in many applications such as the prediction, diagnosis and/or monitoring of pathologies correlated with neutrophil activation and/or destruction; the evaluation of drugs and/or immunomodulators; the assessment of immune responses, either natural and/or after treatment with immunomodulators and/or drugs; and the study of cells and their ability to fight microorganisms and/or to destroy them.