Patents by Inventor Thierry Guillemin

Thierry Guillemin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for purifying plasmid DNA
    Publication number: 20070213289
    Abstract: This invention provides a process for the continuous alkaline lysis of a bacterial suspension in order to harvest pDNA. It further provides for optional additional purification steps, including lysate filtration, anion exchange chromatography, triplex affinity chromatogragphy, and hydrophobic interaction chromatography. These optional purification steps can be combined with the continuous lysis in order to produce a highly purified pDNA product substantially free of gDNA, RNA, protein, endotoxin, and other contaminants.
    Type: Application
    Filed: October 18, 2006
    Publication date: September 13, 2007
    Applicant: CENTELION
    Inventors: Francis Blanche, Michel Couder, Nicolas Maestrali, Thierry Guillemin, David Gaillac
  • Method of preparation for pharmaceutical grade plasmid DNA
    Publication number: 20070111221
    Abstract: This invention provides a process for the continuous alkaline lysis of a bacterial suspension in order to harvest pDNA. It further provides for optional additional purification steps, including lysate filtration, anion exchange chromatography, triplex affinity chromatography, and hydrophobic interaction chromatography. These optional purification steps can be combined with the continuous lysis in order to produce a highly purified pDNA product substantially free of gDNA, RNA, protein, endotoxin, and other contaminants.
    Type: Application
    Filed: March 17, 2006
    Publication date: May 17, 2007
    Inventors: Francis Blanche, Michel Couder, Nicolas Maestrali, David Gaillac, Thierry Guillemin