Patents by Inventor Thierry Magnaldo

Thierry Magnaldo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN EPITHELIAL CELL LINE FOR 3-D MODELIZING OF CANCER AND TREATMENT THEREOF
    Publication number: 20190242874
    Abstract: A cellular model is described that targets dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described is a screening method using this cellular model to screen for pharmacological compounds that can treat or prevent skin cancer, in particular, Basal Cell Carcinoma (BCC) lesions.
    Type: Application
    Filed: October 10, 2018
    Publication date: August 8, 2019
    Inventors: Elodie Burty, Thierry Magnaldo, Yannick Gache, Jérôme Aubert
  • Human keratinocytes PTCH1 cell line
    Patent number: 9902934
    Abstract: A cellular model is described for targeting dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described, is a screening method using this cellular model to screen for pharmacological compounds that can treat or prevent skin cancer and, in particular, Basal Cell Carinoma (BCC) lesions.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: February 27, 2018
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Elodie Burty, Thierry Magnaldo, Yannick Gache
  • HUMAN EPITHELIAL CELL LINE FOR 3-D MODELIZING OF CANCER AND TREATMENT THEREOF
    Publication number: 20170023549
    Abstract: A cellular model is described that targets dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described, is a screening method using this cellular model to screen for pharmacological compounds that can treat or prevent skin cancer, in particular, Basal Cell Carcinoma (BCC) lesions.
    Type: Application
    Filed: February 25, 2016
    Publication date: January 26, 2017
    Inventors: Elodie BURTY, Thierry MAGNALDO, Yannick GACHE, Jérôme AUBERT
  • HUMAN EPITHELIAL CELL LINE FOR 3-D MODELIZING OF CANCER AND TREATMENT THEREOF
    Publication number: 20140243523
    Abstract: A cellular model is described that targets dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described, is a screening method using this cellular model to screen for pharmacological compounds that can treat or prevent skin cancer, in particular, Basal Cell Carcinoma (BCC) lesions.
    Type: Application
    Filed: September 24, 2012
    Publication date: August 28, 2014
    Applicants: GALDERMA RESEARCH & DEVELOPMENT, CNRS
    Inventors: Elodie Burty, Thierry Magnaldo, Yannick Gache, Jérôme Aubert
  • HUMAN KERATINOCYTES PTCH1 CELL LINE
    Publication number: 20140234852
    Abstract: A cellular model is described for targeting dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described, is a screening method using this cellular mod& to screen for pharmacological compounds that can treat or prevent skin cancer and, in particular, Basal Cell Carinoma (BCC) lesions.
    Type: Application
    Filed: September 24, 2012
    Publication date: August 21, 2014
    Applicants: GALDERMA RESEARCH & DEVELOPMENT, CNRS
    Inventors: Elodie Burty, Thierry Magnaldo, Yannick Gache
  • FIBROBLASTS CELLULAR MODEL FOR ASSESSING EFFICACY OF CANCER TREATMENTS BY SHH/PTCH PATHWAY ANTAGONISTS
    Publication number: 20140235856
    Abstract: A cellular model is described that targets dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described, is a screening method using this cellular model to screen for pharmacological compounds that can treat or prevent skin cancer, in particular, Basal Cell Carcinoma, (BCC) lesions.
    Type: Application
    Filed: September 24, 2012
    Publication date: August 21, 2014
    Inventors: Elodie Burty, Thierry Magnaldo, Yannick Gache
  • METHOD FOR DETERMINING A PREDISPOSITION TO BASAL CELL CARCINOMA AND FOR SCREENING TREATMENTS THEREOF
    Publication number: 20110136685
    Abstract: The present invention relates to methods for detecting a predisposition to a basal cell carcinoma and methods for screening a treatment of a basal cell carcinoma.
    Type: Application
    Filed: August 4, 2009
    Publication date: June 9, 2011
    Applicants: INSTITUT GUSTAVE ROUSSY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS DIDEROT - PARIS 7, UNIVERSITE PARIS-SUD XI
    Inventors: Alexandre Valin, Thierry Magnaldo
  • Use of the cd24 marker gene for the selection of keratinocyte stem cells transformed by exogenous sequences
    Publication number: 20040253720
    Abstract: A subject of the present invention is the use of the CD24 marker gene of mammals, such as the human CD24 gene, for the transformation of stem keratinocytes in the implementation of processes for preparing homogenous batches of epidermal stem cells transformed in order to contain an exogenous nucleotide sequence of interest, as well as said stem keratinocytes thus transformed, the epidermal tissue reconstituted starting with these keratinocytes, and their uses.
    Type: Application
    Filed: August 13, 2004
    Publication date: December 16, 2004
    Inventors: Thierry Magnaldo, Alain Sarasin