Patents by Inventor Thierry Muller

Thierry Muller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100197484
    Abstract: The present invention relates to a process for preparing mineral particles (p) from mineral species precursors, said process comprising a step (E) in which a fluid medium (F) containing said precursors in solution and/or dispersed in a solvent is injected into a reactor containing CO2 in the supercritical state by way of an injection nozzle opening into a zone where the supercritical CO2 is at a temperature greater than or equal to the temperature for conversion of the precursors into corresponding mineral species. The invention also relates to the particles (p) as obtained by the process, as well as uses thereof.
    Type: Application
    Filed: April 23, 2008
    Publication date: August 5, 2010
    Applicants: AREVA NP, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Beatrice Sala, Stephanie Willemin, Joel Mazoyer, Thierry Muller, Nathalie Masquelez, Didier Cot, Anne Julbe, Pierre Guillermier
  • Patent number: 7691900
    Abstract: The invention relates to any isolated or synthetic compound and, in particular, to compounds having formula which can: modulate the cell specification of neural stem cells, promote the differentiation and subsequent survival of differentiating glial cells and neurones, and promote the differentiation of oligodendrocyte precursor cells into mature oligodendrocytes. In addition, the inventive compounds can reduce the inflammatory component of diseases that affect the nervous system, for example, by reducing activation of the microglia an/or astrocytes and/or by reducing reactive gliosis. The invention also relates to the methods of preparing such compounds and to the use of same in the preparation of a pharmaceutical composition that is intended for the prevention or treatment of diseases that affect the nervous system. More specifically, the inventive compounds have general formula.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: April 6, 2010
    Assignee: AxoGlia Therapeutics S.A.
    Inventors: Bang Luu, Paul Heuschling, Thierry Muller, Eleonora Morga
  • Publication number: 20090141848
    Abstract: The invention relates to a nuclear reactor primary circuit comprising a primary pipeline (30), which defines an internal volume (32) and in which a primary nuclear reactor coolant downwardly runs, an additional pipeline (26) which is branched to the primary pipeline (30) and defines an internal volume communicating with the internal volume (32) of the primary pipeline (30) and a cuff (36) whose first end (50) is connected to the additional pipeline (26) and the second free end (52) is positioned in the internal volume (32) of the primary pipeline (30). According to said invention, the second end (52) is delimited by a free peripherial edge (53) comprising at least one upstream and downstream sections (56, 58) which are oriented towards the upstream, wherein the upstream section (56) penetrates into the internal volume (32) deeper from the primary pipeline (30) than the downstream section (58).
    Type: Application
    Filed: November 14, 2006
    Publication date: June 4, 2009
    Applicant: AREVA NP
    Inventors: Guy Barois, Jean-Georges Alibaud, Thierry Muller, Christelle Dumez
  • Publication number: 20070177709
    Abstract: The invention relates to a pressurised water nuclear reactor vessel, comprising: an outer casing which comprises at least one cylindrical shell and a dished bottom head, a core support plate, a vessel bottom head space being delimited between the support plate and the dished bottom head, the support plate being perforated with holes for circulation of the primary coolant which place the vessel bottom head space in communication with the core, a calming device which is arranged in the vessel bottom head space, wherein the calming device comprises at least one calming plate which is substantially perpendicular relative to the centre axis of the vessel and a plurality of calming holes, the calming holes being provided in the calming plate and being capable of calming the primary coolant by passing the fluid through the holes.
    Type: Application
    Filed: November 2, 2006
    Publication date: August 2, 2007
    Applicant: AREVA NP
    Inventors: Thierry Muller, Philippe Dolleans, Fabien Hensch
  • Publication number: 20070105946
    Abstract: The invention relates to any isolated or synthetic compound and, in particular, to compounds having formula which can: modulate the cell specification of neural stem cells, promote the differentiation and subsequent survival of differentiating glial cells and neurones, and promote the differentiation of oligodendrocyte precursor cells into mature oligodendrocytes. In addition, the inventive compounds can reduce the inflammatory component of diseases that affect the nervous system, for example, by reducing activation of the microglia an/or astrocytes and/or by reducing reactive gliosis. The invention also relates to the methods of preparing such compounds and to the use of same in the preparation of a pharmaceutical composition that is intended for the prevention or treatment of diseases that affect the nervous system. More specifically, the inventive compounds have general formula.
    Type: Application
    Filed: September 24, 2004
    Publication date: May 10, 2007
    Applicants: UNIVERSITE LOUIS PASTEUR, CENTRAL NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU LUXEMBOURG
    Inventors: Bang Luu, Paul Heuschling, Thierry Muller, Eleonora Morga
  • Publication number: 20070076840
    Abstract: The nuclear fuel assembly having nuclear fuel rods and a support skeleton having two nozzles, guide tubes interconnecting the nozzles, and spacer grids for holding the rods, the grids being secured to the guide tubes. The assembly further has at least one lattice reinforcing device for reinforcing the support skeleton. The reinforcing device is placed between two spacer grids and is secured to the guide tubes. The invention is applicable to fuel assemblies for pressurized water reactors.
    Type: Application
    Filed: September 22, 2004
    Publication date: April 5, 2007
    Inventors: Angelo Beati, Thierry Muller, Jean-Francois Rondemerre