Patents by Inventor Thierry Sifferlen

Thierry Sifferlen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclononene derivaties
    Publication number: 20090306123
    Abstract: The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: August 22, 2005
    Publication date: December 10, 2009
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Olivier Corminboeuf, Walter Fischli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • NOVEL SULFONAMIDE COMPOUNDS
    Publication number: 20090275588
    Abstract: The invention relates to novel sulfonamide compounds and their use as orexin receptor antagonists.
    Type: Application
    Filed: April 10, 2007
    Publication date: November 5, 2009
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Christoph Boss, Markus Gude, Ralf Koberstein, Thierry Sifferlen, Cornella Zumbrunn Acklin
  • Quinoxalin-3-one derivatives as orexin receptor antagonists
    Patent number: 7538109
    Abstract: The invention relates to quinoxalinone derivatives of general Formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: May 26, 2009
    Assignee: Actelion Pharmaceuticals Ltd
    Inventors: Hamed Aissaoui, Martine Clozel, Thomas Weller, Ralf Koberstein, Thierry Sifferlen
  • PYRAZOLO-TETRAHYDRO PYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20090099228
    Abstract: The invention relates to novel pyrazolo-tetrahydropyridines compounds and their use as orexin receptor antagonists.
    Type: Application
    Filed: April 25, 2007
    Publication date: April 16, 2009
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Christoph Boss, Markus Gude, Ralf Koberstein, Thierry Sifferlen
  • Sulfonylamino-acetic acid derivatives
    Patent number: 7435815
    Abstract: The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: October 14, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thierry Sifferlen, Thomas Weller
  • Novel Tetrahydropyridine Derivatives
    Publication number: 20080234305
    Abstract: The invention relates to novel tetrahydropyridine derivatives and use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: October 5, 2004
    Publication date: September 25, 2008
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Novel Piperidine Carboxylic Acid Amide Derivatives
    Publication number: 20080214598
    Abstract: The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 4, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Austin Chih-Yu Chen, Olivier Corminboeuf, Daniel Dube, Walter Fischli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Michel Therien, Thomas Weller
  • Diazabicyclononene Derivatives and Use Thereof
    Publication number: 20080161313
    Abstract: The invention relates to a novel 3,9-diazabicycl?[3.3.1]nonene derivative of formula (I) and the enantiomers thereof and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing at least one compound of formula (I) or (I?) and especially their use as inhibitors of renin.(I).
    Type: Application
    Filed: January 26, 2006
    Publication date: July 3, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Oliver Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Novel Diazabicyclononene Derivative
    Publication number: 20080103152
    Abstract: The invention relates to a novel 3,9-diazabicyclo[3.3.1]nonene derivative and the enantiomers thereof and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing at least one compound of formula (I) or (I?) and especially their use as inhibitors of renin.
    Type: Application
    Filed: December 8, 2005
    Publication date: May 1, 2008
    Applicant: Actelion Pharmaceuticals Ltd
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fisciili, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Hans-Peter Weber, Thomas Weller
  • SULFONYLAMINO-ACETIC ACID DERIVATIVES
    Publication number: 20070244156
    Abstract: The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Application
    Filed: May 31, 2007
    Publication date: October 18, 2007
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thierry Sifferlen, Thomas Weller
  • Sulfonylamino-acetic acid derivatives
    Patent number: 7279578
    Abstract: The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: October 9, 2007
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thierry Sifferlen, Thomas Weller
  • Novel diazabicyclonene derivatives and use thereof
    Publication number: 20070142363
    Abstract: The invention relates to novel derivatives and related compounds and their use as active ingredients in the prepa- ration of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: October 7, 2004
    Publication date: June 21, 2007
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Novel diazabicyclononene and tetrahydropyridine derivatives with a new polar side-chain
    Publication number: 20070135405
    Abstract: The invention relates to novel bicyclic derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: October 18, 2004
    Publication date: June 14, 2007
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Diazabicyclononene and tetrahydropyridine derivatives with a new side-chain
    Publication number: 20070135406
    Abstract: The invention relates to novel bicyclic derivatives, and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: November 30, 2004
    Publication date: June 14, 2007
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Novel diazabicyclononene derivatives and use
    Publication number: 20070111989
    Abstract: The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I), wherein Z is 0 or 1, one of m, n is 0 and the other is 1, and their use as inhibitors of renin.
    Type: Application
    Filed: November 30, 2004
    Publication date: May 17, 2007
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Benzazepines and related heterocyclic derivatives which are useful as orexin receptor antagonists
    Patent number: 7192950
    Abstract: The invention relates to novel benzazepines and related heterocyclic derivatives (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: March 20, 2007
    Assignee: Actelion Pharmaceuticals, Ltd.
    Inventors: Hamed Aissaoui, Martine Clozel, Thomas Weller, Ralf Koberstein, Thierry Sifferlen, Walter Fischli
  • Quinoxalinone-3-one derivatives as orexin receptor antagonists
    Publication number: 20070027157
    Abstract: The invention relates to quinoxalinone derivatives of general Formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Application
    Filed: April 26, 2004
    Publication date: February 1, 2007
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Hamed Aissaoui, Martine Clozel, Thomas Weller, Ralf Koberstein, Thierry Sifferlen
  • 9-Azabicyclo'3.3.1 inon-6-ee derivatives with a heteroatom at the 3-position as renin inhibitors
    Publication number: 20060258648
    Abstract: The invention relates to novel 9-azabicyclo[3.3.1]nonene derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: April 26, 2004
    Publication date: November 16, 2006
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thomas Weller, Thierry Sifferlen
  • Novel diazabicyclononene derivatives
    Publication number: 20060223795
    Abstract: The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 5, 2006
    Inventors: Oliver Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thomas Weller, Thierry Sifferlen
  • Tropane derivatives and their use as ace inhibitors
    Publication number: 20060205768
    Abstract: The invention relates to novel tropane derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: April 26, 2004
    Publication date: September 14, 2006
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thomas Weller, Thierry Sifferlen