Patents by Inventor Thijs Kaper

Thijs Kaper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250051748
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: December 15, 2022
    Publication date: February 13, 2025
    Inventors: Viktor Yuryevich Alekseyev, Lilia Babe, Lydia Dankmeyer, Frits Goedegebuur, Roopa Ghirnikar, Thijs Kaper, Harm Mulder, Nils Henning Redestig, Sander Van Stigt Thans
  • Publication number: 20240279632
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability compared to one or more reference subtilisin.
    Type: Application
    Filed: April 19, 2024
    Publication date: August 22, 2024
    Inventors: Lilia Maria Babe, Viktor Yuryevich Alekseyev, Joshua Roy Basler, H. Billur Engin, David A. Estell, Roopa Santosh Ghirnikar, Frits Goedegebuur, Thijs Kaper, Mulder Harm, Sina Pricelius, Sander Van Stigt Thans, Gudrun Vogtentanz
  • Publication number: 20240263162
    Abstract: Cleaning compositions particularly for laundry, can include one or more subtilisin variant and cleaning adjunct. Methods of treating surfaces, particularly fabrics, can include contacting the surface with an aqueous wash liquor having the cleaning composition therein. The subtilisin variant may have improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: February 1, 2024
    Publication date: August 8, 2024
    Inventors: Lilia Maria Babe, Joshua Roy Basler, Neil Bradley, David Aaron Estell, Adam Garske, Michelle Jackson, Thijs Kaper, Karolina Anna Korzycka, Michael Stoner
  • Publication number: 20240174953
    Abstract: Described herein is at least one novel trypsin-like serine protease polypeptide and uses thereof. Further described herein are cleaning compositions containing at least one polypeptide described herein, wherein said composition can be used to clean fabrics and hard surfaces. Even further described herein is at least one cleaning composition selected from a laundry detergent, a dishwashing detergent (e.g., automatic and hand dish), and a personal care composition. Even still further, at least one polypeptide having improved soil removal and/or stability compared to at least one reference polypeptide is described herein.
    Type: Application
    Filed: April 21, 2022
    Publication date: May 30, 2024
    Inventors: Lilia M Babe, Xiaogang Gu, Thijs Kaper
  • Publication number: 20240166973
    Abstract: Fabric and home care compositions including a surfactant and a protease. The automatic dishwashing composition is in the form of a water-soluble unit-dose pouch including a compartment. The compartment includes both a powder component and a gel component. The protease is a subtilisin variant that includes: (i) a mutation at position 122; and (ii) one or more mutations at positions 126, 127, 128, 211 and 212, with reference to SEQ ID NO: 1. The variant has at least about 80% identity to the amino acid sequence of SEQ ID NO: 1.
    Type: Application
    Filed: December 14, 2022
    Publication date: May 23, 2024
    Inventors: Michelle JACKSON, Karolina Anna KORZYCKA, Carly PICKERING, Philip Frank SOUTER, Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Lydia DANKMEYER, Roopa Santosh GHIRNIKAR, Frits GOEDEGEBUUR, Thijs KAPER, Harm Jan MULDER, Nils Henning REDESTIG, Sander VAN STIGT-THANS
  • Patent number: 11946081
    Abstract: Disclosed herein is one or more subtilisin variant. nucleic acid encoding same. and compositions and methods related to the production and use thereof. including one or more Bacillus gibsonii-clade subtilisin variant that has improved soil removal compared to one or more reference subtilisin.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: April 2, 2024
    Assignee: Danisco US Inc.
    Inventors: Lilia Maria Babe, Lydia Dankmeyer, Frits Goedegebuur, Thijs Kaper, Harm Mulder, Sina Pricelius
  • Publication number: 20240101933
    Abstract: A phosphate-free automatic dishwashing cleaning composition comprising i) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 and comprising at least one amino acid substitution (using the SEQ ID NO: 1 numbering) selected from the group consisting of X54T; X126A, D, G, V, E, K, I; X127E, S, T, A, P, G, C; and X128E, C, T, D, P, G, L, Y, N; and ii) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.
    Type: Application
    Filed: October 27, 2023
    Publication date: March 28, 2024
    Inventors: Michelle JACKSON, Eva Maria PEREZ-PRAT de VINUESA, David John TARBIT, Philip Frank SOUTER, Lilia Maria BABE, David Aaron ESTELL, Frits GOEDEGEBUUR, Harm Jan MULDER, Sina PRICELIUS, Lydia DANKMEYER, Thijs KAPER, Hatice Billur ENGIN
  • Patent number: 11834634
    Abstract: A phosphate-free automatic dishwashing cleaning composition comprising i) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 and comprising at least one amino acid substitution (using the SEQ ID NO: 1 numbering) selected from the group consisting of X54T; X126A, D, G, V, E, K, I; X127E, S, T, A, P, G, C; and X128E, C, T, D, P, G, L, Y, N; and ii) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: December 5, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Michelle Jackson, Eva Maria Perez-Prat de Vinuesa, David John Tarbit, Philip Frank Souter, Lilia Maria Babe, David Aaron Estell, Frits Goedegebuur, Harm Jan Mulder, Sina Pricelius, Lydia Dankmeyer, Thijs Kaper, Hatice Billur Engin
  • Publication number: 20230365897
    Abstract: Fabric and home care compositions including a surfactant and a protease.
    Type: Application
    Filed: December 14, 2022
    Publication date: November 16, 2023
    Inventors: Michelle JACKSON, Karolina Anna KORZYCKA, Carly PICKERING, Philip Frank SOUTER, Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Lydia DANKMEYER, Roopa Santosh GHIRNIKAR, Frits GOEDEGEBUUR, Thijs KAPER, Harm Jan MULDER, Nils Henning REDESTIG, Sander VAN STIGT-THANS
  • Publication number: 20230257728
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: February 9, 2023
    Publication date: August 17, 2023
    Inventors: Lilia Maria Babe, Lydia Dankmeyer, David A. Estell, Frits Goedegebuur, Thijs Kaper, Harm Mulder, Sina Pricelius
  • Publication number: 20230203406
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Application
    Filed: August 2, 2022
    Publication date: June 29, 2023
    Inventors: Lilia Maria BABE, Frits GOEDEGEBUUR, Thijs KAPER, Sina PRICELIUS, Eva Maria PEREZ-PRAT VINUESA, Michelle JACKSON, Carly PICKERING, Philip Frank SOUTER
  • Publication number: 20230028935
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability compared to one or more reference subtilisin.
    Type: Application
    Filed: November 25, 2019
    Publication date: January 26, 2023
    Inventors: Lilia Maria BABE, Viktor Yuryevich ALEKSEYEV, Joshua Roy BASLER, H. Billur ENGIN, David A. ESTELL, Roopa Santosh GHIRNIKAR, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Nils Henning REDESTIG, Sander VAN STIGT THANS
  • Patent number: 11492571
    Abstract: A phosphate-free automatic dishwashing cleaning composition comprising a protease wherein the protease has at least 80%, preferably at least 85%, more preferably at least 90% and especially at least 96% identity with the amino acid sequence of SEQ ID NO:1 or with the amino acid sequence of SEQ ID NO:2 and wherein the protease comprises amino acid substitutions selected from the group consisting of: (i) at least two amino acid substitutions selected from the group consisting of: X198G/A/K/L/Q/R/T/V/S/L, X207Q, X211Q/N and X212Q in combination with at least three amino acid substitutions selected from the group consisting of: X039E, X074D, X099R, X126A, X127E and X128G; or (ii) X039E-X074D-X099R-X116R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X211N; X039E-X074D-X099R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X207Q; or (iii) any of the proteases of (i) and (ii) further comprising at least one amino acid substitution selected from X242D and X256E; or (iv) X039E-X074D-X099R
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: November 8, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Eva Maria Perez-Prat Vinuesa, Michelle Jackson, Carly Pickering, Viktor Yuryevich Alekseyev, Lilia Maria Babe, Frits Goedegebuur, Thijs Kaper, Sina Pricelius, Sander Van Stigt Thans, Harm Mulder, Nils Henning Redestig, Lydia Dankmeyer, Michael Stoner, Adam Garske, Roopa Santosh Ghirnikar
  • Patent number: 11421189
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: August 23, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Lilia Maria Babe, Frits Goedegebuur, Thijs Kaper, Sina Pricelius, Eva Maria Perez-Prat Vinuesa, Michelle Jackson, Carly Pickering, Philip Frank Souter
  • Publication number: 20220220419
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 20, 2020
    Publication date: July 14, 2022
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Lydia DANKMEYER, Adam GARSKE, Roopa Santosh GHIRNIKAR, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Nils Henning REDESTIG, Michael STONER, Sander VAN STIGT THANS
  • Publication number: 20220098524
    Abstract: A phosphate-free automatic dishwashing cleaning composition including: a) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 or SEQ ID NO:2 including two negatively charged amino acid residues, aspartic acid (D) and/or glutamic acid (E), in positions 124-131 using the SEQ ID NO: 1 numbering and the SEQ ID NO:2, respectively; and b) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.
    Type: Application
    Filed: October 22, 2021
    Publication date: March 31, 2022
    Inventors: Philip Frank SOUTER, Eva Maria PEREZ-PRAT de VINUESA, Lilia Maria BABE, David Aaron ESTELL, Frits GOEDEGEBUUR, Harm Jan MULDER, Sina PRICELIUS, Lydia DANKMEYER, Thijs KAPER, Hatice Billur ENGIN
  • Patent number: 11220656
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: January 11, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Frits Goedegebuur, David Aaron Estell, Lilia Maria Babe, Thijs Kaper, Viktor Alekseyev, Sina Pricelius, Hatice Billur Engin, Harm Jan Mulder, Sander Van Stigt-Thans, Eva Maria Perez-Prat Vinuesa
  • Publication number: 20210363470
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 24, 2019
    Publication date: November 25, 2021
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Billur H. ENGIN, David A. ESTELL, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Sander Van Stigt THANS
  • Publication number: 20210214703
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 15, 2021
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Billur H. ENGIN, David A. ESTELL, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Sander Van Stigt THANS
  • Publication number: 20210122997
    Abstract: A phosphate-free automatic dishwashing cleaning composition comprising a protease wherein the protease has at least 80%, preferably at least 85%, more preferably at least 90% and especially at least 96% identity with the amino acid sequence of SEQ ID NO:1 or with the amino acid sequence of SEQ ID NO:2 and wherein the protease comprises amino acid substitutions selected from the group consisting of: (i) at least two amino acid substitutions selected from the group consisting of: X198G/A/K/L/Q/R/T/V/S/L, X207Q, X211Q/N and X212Q in combination with at least three amino acid substitutions selected from the group consisting of: X039E, X074D, X099R, X126A, X127E and X128G; or (ii) X039E-X074D-X099R-X116R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X211N; X039E-X074D-X099R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X207Q; or (iii) any of the proteases of (i) and (ii) further comprising at least one amino acid substitution selected from X242D and X256E; or (iv) X039E-X074D-X099R
    Type: Application
    Filed: October 9, 2020
    Publication date: April 29, 2021
    Inventors: Philip Frank SOUTER, Eva Maria PEREZ-PRAT VINUESA, Michelle JACKSON, Carly PICKERING, Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Frits GOEDEGEBUUR, Thijs KAPER, Sina PRICELIUS, Sander VAN STIGT THANS, Harm MULDER, Nils Henning REDESTIG, Lydia DANKMEYER, Michael STONER, Adam GARSKE, Roopa Santosh GHIRNIKAR