Abstract: The device relates to a method and a device (10) for determining an irradiation plan for a particle irradiation unit (20). In the method, a target volume (6) within a test object (14; 18) is irradiated with a particle beam (16) using the particle irradiation unit (20) according to the irradiation plan. The radiation plan is determined in order to apply the energy of the particle beam (16) according to a predetermined dose distribution in the target volume (6), the target volume (6) and the predetermined dose distribution being pre-set. When determining the irradiation plan, irradiation duration is also taken into account, the irradiation plan being determined such that the irradiation duration is as short as possible.

Abstract: A method for creating a first data set for modifying an irradiation plan parameter data set used for controlling an irradiation system for irradiating a target volume in an irradiation volume using an ion beam includes defining a sensitive volume within the biological material to be irradiated, determining a fluence distribution of the ion beam, determining a microscopic dose distribution of the ion beam, determining, from the microscopic dose distribution of the ion beam, a spatial microscopic damage distribution of the ion beam, determining an expected value for a number of correlated damage events in a sub-micrometer range in the sensitive volume from the spatial microscopic damage distribution of the ion beam in the sensitive volume, determining the effect of the ion beam on the biological material, and storing data that indicate the effect of the ion beam on the material.

Abstract: A method is provided for detecting a movement of a body between acquisition times of at least two acquisition data sets, wherein, for virtual sectional planes of the body, a first intermediate function value of attenuation values of all the body elements lying in the sectional plane is determined based on a first acquisition data set, and a second intermediate function value of the attenuation values is determined based on a second acquisition data set. For each sectional plane, a difference value is determined from the intermediate function values. A total error value for the two acquisition data sets is calculated by combining the difference values of all the sectional planes. The virtual sectional planes have a common line of intersection, and for the particular acquisition time, the difference between pairs of the sectional lines is at least one pixel.

Abstract: A target volume within a test object is irradiated according to an irradiation plan with a particle beam using a particle irradiation unit. The irradiation plan is determined in order to apply the energy of the particle beam in the target volume according to a predetermined dose distribution. In addition, a boundary condition is specified for at least one of the isoenergy layers and the irradiation plan is additionally specified such that the boundary condition is met for the at least one isoenergy layer. The boundary condition includes one or more of a minimum boundary energy, a maximum boundary energy, a minimum grid point number, a minimum total particle number, a minimum total dose, a minimum dose contribution to a total dose to be administered, a minimum contribution to a target function which is calculated for determining the irradiation plan, and a minimum dose compensation error.

Abstract: A method is provided for detecting a movement of a body between acquisition times of at least two acquisition data sets, wherein, for virtual sectional planes of the body, a first intermediate function value of attenuation values of all the body elements lying in the sectional plane is determined based on a first acquisition data set, and a second intermediate function value of the attenuation values is determined based on a second acquisition data set. For each sectional plane, a difference value is determined from the intermediate function values. A total error value for the two acquisition data sets is calculated by combining the difference values of all the sectional planes. The virtual sectional planes have a common line of intersection, and for the particular acquisition time, the difference between pairs of the sectional lines is at least one pixel.

Abstract: A method for creating a first data set for modifying an irradiation plan parameter data set used for controlling an irradiation system for irradiating a target volume in an irradiation volume using an ion beam includes defining a sensitive volume within the biological material to be irradiated, determining a fluence distribution of the ion beam, determining a microscopic dose distribution of the ion beam, determining, from the microscopic dose distribution of the ion beam, a spatial microscopic damage distribution of the ion beam, determining an expected value for a number of correlated damage events in a sub-micrometer range in the sensitive volume from the spatial microscopic damage distribution of the ion beam in the sensitive volume, determining the effect of the ion beam on the biological material, and storing data that indicate the effect of the ion beam on the material.

Abstract: An irradiation plan for a particle irradiation unit is determined in a first run based on a specified target volume in a test object and a specified dose distribution to apply the particle beam in the target volume. The target volume includes a plurality of isoenergy layers. The irradiation plan may be determined in a second run with an additional condition that at least one of the isoenergy layers, determined according to one or more criteria, is not irradiated. Alternatively, the irradiation plan may be determined in a second run with an additional condition that only certain isoenergy layers, determined according to one or more criteria, are irradiated.

Abstract: An irradiation plan for a particle irradiation unit is determined in a first run based on a specified target volume in a test object and a specified dose distribution to apply the particle beam in the target volume. The target volume includes a plurality of isoenergy layers. The irradiation plan may be determined in a second run with an additional condition that at least one of the isoenergy layers, determined according to one or more criteria, is not irradiated. Alternatively, the irradiation plan may be determined in a second run with an additional condition that only certain isoenergy layers, determined according to one or more criteria, are irradiated.

Abstract: A target volume within a test object is irradiated according to an irradiation plan with a particle beam using a particle irradiation unit. The irradiation plan is determined in order to apply the energy of the particle beam in the target volume according to a predetermined dose distribution. In addition, a boundary condition is specified for at least one of the isoenergy layers and the irradiation plan is additionally specified such that the boundary condition is met for the at least one isoenergy layer. The boundary condition includes one or more of a minimum boundary energy, a maximum boundary energy, a minimum grid point number, a minimum total particle number, a minimum total dose, a minimum dose contribution to a total dose to be administered, a minimum contribution to a target function which is calculated for determining the irradiation plan, and a minimum dose compensation error.

Abstract: The device relates to a method and a device (10) for determining an irradiation plan for a particle irradiation unit (20). In the method, a target volume (6) within a test object (14; 18) is irradiated with a particle beam (16) using the particle irradiation unit (20) according to the irradiation plan. The radiation plan is determined in order to apply the energy of the particle beam (16) according to a predetermined dose distribution in the target volume (6), the target volume (6) and the predetermined dose distribution being pre-set. When determining the irradiation plan, irradiation duration is also taken into account, the irradiation plan being determined such that the irradiation duration is as short as possible.

Abstract: A method for determining an action of a particle beam on a material at least partially irradiated or to be irradiated by the particle beam includes providing at least one particle beam parameter of the particle beam and at least one material property parameter of the material. A microscopic damage correlation is performed and the at least one particle beam parameter of the particle beam and that at least one material property parameter of the material are used so as to determine the action of the particle beam on the material.