Abstract: The invention is in the field of analytical technique and relates to an improved procedure for determining the concentration or activity of an analyte, an analyte-dependent detection reaction being set in motion and the reaction kinetics determined being evaluated. The procedure makes possible an individual determination of the lag phase of the reaction kinetics for each measurement.

Abstract: The present invention relates to a chromogenic test reagent which comprises a chromogenic peptide substrate and an inhibitor of fibrin polymerization, which is particularly suitable for being used in coagulation-diagnostic tests and which is distinguished by the fact that it exhibits a nigh degree of stability and/or a long shelf life in the liquid state.

Abstract: The present invention relates to a method for automatically determining the endogenous thrombin potential of a blood or plasma sample.

Abstract: The present invention relates to macromolecular polysaccharide-peptide conjugates which contain a peptide portion which C-terminally contains the amino acid sequence Ala-Gly-Arg, which is cleaved by thrombin.

Abstract: The invention is in the field of analytical technique and relates to an improved procedure for determining the concentration or activity of an analyte, an analyte-dependent detection reaction being set in motion and the reaction kinetics determined being evaluated. The procedure makes possible an individual determination of the lag phase of the reaction kinetics for each measurement.

Abstract: The present invention relates to macromolecular polysaccharide-peptide conjugates which contain a peptide portion which C-terminally contains the amino acid sequence Ala-Gly-Arg, which is cleaved by thrombin.

Abstract: The present invention relates to a chromogenic test reagent which comprises a chromogenic peptide substrate and an inhibitor of fibrin polymerization, which is particularly suitable for being used in coagulation-diagnostic tests and which is distinguished by the fact that it exhibits a nigh degree of stability and/or a long shelf life in the liquid state.

Abstract: The present invention relates to a method for automatically determining the endogenous thrombin potential of a blood or plasma sample.

Abstract: Delipidized plasma preparations which possess prothrombin concentrations which are set in a defined manner and which are lower or higher than those in normal human plasma are suitable for calibrating, standardizing and controlling thrombin activity tests and thrombin generation tests such as ETP tests. The plasma preparations are produced using a prothrombin-deficient plasma, which is obtained from normal plasma by means of immunoadsorption, for example, and can additionally comprise buffering substances, proteinase inhibitors, anticoagulants, stabilizers and/or other auxiliary substances and additives which are customary when preparing plasmas.