Patents by Inventor Thilo Kohler

Thilo Kohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for assessing the virulence of pathogens and uses thereof
    Publication number: 20070166781
    Abstract: The present invention relates to a method of assessing the virulence of a pathogen or a toxin to a host organism. The present invention further relates to a method to identify a composition that reduces the virulence of a pathogen or toxin to a host organism. The invention also relates to a method to identify genes encoding toxins or factors that are pathogenic to a host organism.
    Type: Application
    Filed: February 26, 2007
    Publication date: July 19, 2007
    Inventors: Pierre Cosson, Jean-Pierre Paccaud, Thilo Kohler
  • Virulence genes, proteins, and their use
    Publication number: 20060171959
    Abstract: A series of genes from Pseudomonas aeruginosa and Klebsiella are shown to encode products that are implicated in virulence. The identification of theses genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used to identify antimicrobial drugs, diagnostic methods for the identification of a pathogen-associated disease, and in the manufacture of vaccines.
    Type: Application
    Filed: December 19, 2003
    Publication date: August 3, 2006
    Inventors: Pierre Cosson, Thilo Kohler, Mohammed Benghezal, Anna Marchetti, Christian Delden
  • Method for assessing the virulence of pathogens and uses thereof
    Publication number: 20040234983
    Abstract: The present invention relates to a method assessing the virulence of a pathogen or toxin to a host organism. The present invention further relates to a method to identify a composition that reduces the virulence of a pathogen or toxin to a host organism. The invention also relates to a method to identify genes encoding toxins or factors that are pathogenic to a host organism.
    Type: Application
    Filed: June 15, 2004
    Publication date: November 25, 2004
    Inventors: Pierre Cosson, Jean-Pierre Paccaud, Thilo Kohler
  • Virulence genes, proteins, and their use
    Publication number: 20040122212
    Abstract: A series of genes from Pseudomonas aeruginosa and Klebsiella are shown to encode products that are implicated in virulence. The identification of these genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used to identify antimicrobial drugs, diagnostic methods for the identification of a pathogen-associated disease, and in the manufacture of vaccines.
    Type: Application
    Filed: December 20, 2002
    Publication date: June 24, 2004
    Inventors: Pierre Cosson, Thilo Kohler, Mohammed Benghezal, Anna Marchetti, Christian van Delden