Patents by Inventor THIRUPATI REDDY KATKURI

THIRUPATI REDDY KATKURI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for increased yield of immunoglobulin from human plasma
    Patent number: 9556253
    Abstract: The present invention discloses a preparation method for large scale production of human immunoglobulins (IgG) with high yields by an improved all-chromatography process scheme that eliminates ethanol precipitation. The process of extracting immunoglobulins is such that the other therapeutic proteins in plasma are left unaffected and are available for extraction separately from the same plasma sample. The yields obtained are in the range of 7 to 8 grams of IgG per liter of plasma. The high yielding process scheme of the present invention comprises of chromatographic steps and viral inactivation or removal steps to obtain a purified immunoglobulin protein that complies with pharmacopoeial limits and is suitable for therapeutic administration (normal intravenous immunoglobulin—IVIG).
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: January 31, 2017
    Assignee: HEMARUS THERAPEUTICS LIMITED
    Inventors: Ashok Kumar Nuvula, Zinia Chakraborty, Vvs Sailesh Bavirisetti, Thirupati Reddy Katkuri, Uma Devi Komath
  • PROCESS FOR INCREASED YIELD OF IMMUNOGLOBULIN FROM HUMAN PLASMA
    Publication number: 20160152690
    Abstract: The present invention discloses a preparation method for large scale production of human immunoglobulins (IgG) with high yields by an improved all-chromatography process scheme that eliminates ethanol precipitation. The process of extracting immunoglobulins is such that the other therapeutic proteins in plasma are left unaffected and are available for extraction separately from the same plasma sample. The yields obtained are in the range of 7 to 8 grams of IgG per liter of plasma. The high yielding process scheme of the present invention comprises of chromatographic steps and viral inactivation or removal steps to obtain a purified immunoglobulin protein that complies with pharmacopoeial limits and is suitable for therapeutic administration (normal intravenous immunoglobulin—IVIG).
    Type: Application
    Filed: December 19, 2014
    Publication date: June 2, 2016
    Applicant: HEMARUS THERAPEUTICS LIMITED
    Inventors: ASHOK KUMAR NUVULA, ZINIA CHAKRABORTY, VVS SAILESH BAVIRISETTI, THIRUPATI REDDY KATKURI, UMA DEVI KOMATH