Patents by Inventor Tho Nguyen-Xuan

Tho Nguyen-Xuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ready-to-use paracetamol injection solutions containing propylene glycol as the only cosolvent
    Patent number: 8178121
    Abstract: The present invention refers to ready-to-use highly stable paracetamol injectable solutions, prepared by mixing paracetamol, water, propylene glycol, and a citrate buffer. (pH 4.5 to 6.5), and by heating said solution under preset conditions. The resulting solution may be stored for an extended period of time within a wide range of temperatures, with no paracetamol precipitation and/or its chemical modification.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: May 15, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: Tho Nguyen-Xuan
  • Injectable liquid formulation of paracetamol
    Patent number: 8071619
    Abstract: The invention relates to a novel injectable liquid formulation of paracetamol, comprising an aqueous solvent, a buffer agent with a pKa between 4.5 and 6.5, an isotonic agent and the dimer of paracetamol of formula (I), a method for preparation of said formulation and the use of said dimer for the stabilisation of a liquid paracetamol pharmaceutical formulation.
    Type: Grant
    Filed: February 16, 2004
    Date of Patent: December 6, 2011
    Inventor: Tho Nguyen-Xuan
  • Injectable liquid formulation of paracetamol
    Publication number: 20060084703
    Abstract: The invention relates to a novel injectable liquid formulation of paracetamol, comprising an aqueous solvent, a buffer agent with a pKa between 4.5 and 6.5, an isotonic agent and the dimer of paracetamol of formula (I), a method for preparation of said formulation and the use of said dimer for the stabilisation of a liquid paracetamol pharmaceutical formulation.
    Type: Application
    Filed: February 16, 2004
    Publication date: April 20, 2006
    Inventor: Tho Nguyen-Xuan
  • Ready-to-use paracetamol injection solutions containing propylene glycol as the only cosolvent
    Publication number: 20040247627
    Abstract: The present invention refers to ready-to-use highly stable paracetamol injectable solutions, prepared by mixing paracetamol, wter, propylene glycol, and a citrate buffer. (pH 4.5 to 6.5), and by heating said solution under preset conditions. The resulting solution may be stored for an extended period of time within a wide range of temperatures, with no paracetamol precipitation and/or its chemical modification.
    Type: Application
    Filed: April 14, 2004
    Publication date: December 9, 2004
    Inventor: Tho Nguyen-Xuan