Abstract: The invention relates to a line device (105) for a ventricular assist system (100), wherein the line device (105) comprises a guide cannula (145), which is structured at least partially along a direction of extent; and, furthermore, the line device (105) comprises an electrical conducting element (145), which is arranged in the guide cannula (140), wherein the electrical conducting element (145) comprises a multilayer structure.

Abstract: The invention relates to a method for determining the speed of sound in a fluid (1) in the region of an implanted, vascular support system (2), comprising the following steps: a) sending an ultrasonic signal (3) by means of an ultrasonic sensor (4) b) reflecting the ultrasonic signal (3) on at least one sound reflector (5), which is visible in the field of vision (6) of the ultrasonic sensor (4) and arranged at a defined distance at least to the ultrasonic sensor (4) or to a further sound reflector (5), c) receiving the reflected ultrasonic signal (8), d) determining the speed of sound in the fluid using the reflected ultrasonic signal (8).

Abstract: A chimeric antigen receptor is disclosed that includes: (a) an scFv comprising a light chain variable domain (VL) and a heavy chain variable domain (VH), wherein the scFv specifically binds to CCR4; (b) a hinge and transmembrane domain from CD8; (c) an intracellular 4-1BB signaling domain; and (d) an intracellular CD3 zeta signaling domain, wherein (a)-(d) are in N to C terminal order. Uses of the chimeric antigen receptor, such as for treating a malignancy, are also disclosed.

Abstract: The invention relates to a motor housing module (110) for sealing a motor compartment of a motor of a heart support system. The motor housing module (110) has at least one feed-through portion (205), at least one feed-through line (210), and at least one contact pin (215). The feed-through portion (205) is designed to establish an electrical connection between the heart support system and a connection cable in order to externally contact the heart support system. The at least one feed-through line (210) is embedded in the feed-through portion (205) and extends through the feed-through portion (205). The feed-through line (210) can be connected to the motor and to the connection cable. A first end of the at least one contact pin (215) is embedded in the feed-through portion (205) and a second end of the contact pin (215) projects from the feed-through portion (205) on a side facing away from the motor compartment.

Abstract: The invention relates to an electronics module (102) for a ventricular assist device, wherein the ventricular assist device has a motor housing for accommodating a pump motor. The electronics module (102) comprises an electronics section (204) for accommodating at least one electronic component (206) and/or at least one electrically conductive contacting element (208), and a coupling section (202) designed as a joint between the motor housing (104) and the electronics section (204) or as a separate component to be joined, wherein the motor housing (104) and the electronics section (204) are combined or can be combined via the coupling section (202) with one another to form a fluid-tight module housing (104) to be arranged in a blood vessel.

Abstract: The invention relates to an implantable vascular support system (10), comprising: —a fluid channel (13) passing through the support system (10) and through which fluid can flow; —a first pressure sensor (18a, b) arranged and configured to determine at least a static pressure or a total pressure in the region of the support system (10); —a second pressure sensor (17) arranged and configured to determine at least a static pressure or a total pressure in the region of the fluid channel (13).

Abstract: An intravascular blood pump (100) comprises a tip (110), a first region (120) with at least one blood through-opening (121), a flow cannula (130), a second region (140) with at least one blood through-opening (141), a motor-operated pump mechanism (150) and a conducting cable (170). At least in the region of the flow cannula (130), at least one electrical conductor track is realized by a surface coating structure.

Abstract: The invention relates to a sensor head device (105) for a heart support system, wherein the sensor head device (105) has at least one sensor carrying element (205), wherein the sensor carrying element (205) has at least one sensor cavity (155, 210) for accommodating at least one sensor (215, 220) and/or at least one signal transmitter cavity (225, 230) for accommodating at least one signal transmitter (235).

Abstract: A waveguide structure for a head up display in which a reflective output coupling structure is formed of a separate, but connected, component to a main waveguide. Light is coupled from the main waveguide to the output coupling structure by evanescent wave coupling. In a method of manufacture for such a waveguide the output coupling structure is attached to the main waveguide using an optical feedback technique.

Abstract: A dental cleaning appliance includes a handle, a fluid reservoir for storing a working fluid, and a fluid delivery system for receiving working fluid from the reservoir, and for delivering working fluid to the oral cavity of a user. A drive unit drives movement of a bristle carrier relative to the handle. The fluid reservoir extends about at least part of the drive unit.

Abstract: A HID solid state retrofit lamp includes a circumferential array of solid state light sources mounted on circuit boards, a heat sink located in the lamp's interior volume, and a fan positioned in the interior volume to force airflow across the heat sink. A capper assembly includes at least one aperture to vent the interior volume, and an intermediate circuit board within the capper assembly. The intermediate circuit board distributes electrical power to the circuit boards by tabs and contacts extending from the boards that are mechanically bonded together. An optical transmissive shield is positioned exterior to the circumferential array, and can include prismatic structures to direct light emitted from the LED sources in an off axis direction.

Abstract: Endpoint agent cSensors can be used to extend network visibility and enhance tracking capabilities for a cyber security and threat defense environment. The cSensor may comprise a network module to monitor network information coming into and out of the endpoint computing device to ingest a first set of traffic data from network connections. The cSensor may have a collation module to collect the first set of traffic data and obtain input data related to observed network events. An analyzer module can receive the input data and use an intelligent DPI engine to perform predetermined levels of DPI from two or more possible levels of DPI on the input data based on network parameters. The cSensor may have a communication module to transmit a second set of traffic data to a cyber security appliance based on the specified DPI performed. Furthermore, the cSensor may have an autonomous action module to perform autonomous action(s) in response to autonomous action(s) correlated to the received second set of traffic data.

Abstract: A method for ascertaining a viewing direction of an eye. A laser beam emitted by a laser source is passed over at least two scanning points on the eye, using a reflection element and a deflecting element. A self-mixing effect of the scanning laser beam reflected by the eye into the laser source is used, in order to determine, for the at least two scanning points, the optical path length from the laser source to the at least two scanning points on the surface of the eye and/or a reflectivity of the eye at the at least two scanning points.

Abstract: Determining interest in promotional content to be displayed at a mobile communication device is described. The promotional content, including a first portion that is visible and a second portion that is hidden in a first state, may be received. The first and second portions are each selectable only when visible. A promotional display that includes the promotional content in the first state is generated. Upon receipt of a first input from the user in relation to the first portion, the promotional content may be transitioned from the first state to a second state such the first portion becomes hidden and the second portion becomes visible. Upon failing to receive a second input from the user in relation to the second portion, the promotional content may be transitioned from the second state to the first state. Upon receipt of the second input, an interest in the promotional content may be indicated.

Abstract: A chimeric antigen receptor is disclosed that includes: (a) an scFv comprising a light chain variable domain (VL) and a heavy chain variable domain (VH), wherein the scFv specifically binds to CCR4; (b) a hinge and transmembrane domain from CD8; (c) an intracellular 4-1BB signaling domain; and (d) an intracellular CD3 zeta signaling domain, wherein (a)-(d) are in N to C terminal order. Uses of the chimeric antigen receptor, such as for treating a malignancy, are also disclosed.

Abstract: An optical imaging system for imaging a target during a medical procedure is disclosed. The optical imaging system includes: a first camera for capturing a first image of the target; a second wide-field camera for capturing a second image of the target; at least one path folding mirror disposed in an optical path between the target and a lens of the second camera; and a processing unit for receiving the first image and the second image, the processor being configured to: apply an image transform to one of the first image and the second wide-field image; and combine the transformed image with the other one of the images to produce a stereoscopic image of the target.

Abstract: A modular wearable optics device including: at least one wearable support element; one or more active optical elements adapted in use to display an image to a user; one of a plurality of bridging elements selected to position or orientate the one or more active optical elements in a predetermined location based on one or more anthropometric characteristics of the user.

Abstract: A scooter includes a diversity of sensors to adapt scooter characteristics to any one or more than one of safety aspects, and scooter, environmental or driver states. Scooter characteristics susceptible to adaptation include throttle response; motor torque; motor speed; speed; maximum current drawn from energy storage system; braking characteristics, such as distribution, maximum braking power, anti-blocking system parameters or braking; adjusting vehicle dynamics, and suspension parameters such as stiffness, or damping coefficient.

Abstract: An image projection system utilising a digital mirror device with pivotable mirrors and an asymmetric angular illumination of the mirrors.

Abstract: Identifying latency-sensitive computing workloads of an information handling system (IHS), including identifying one or more computing parameters of the IHS; monitoring a value of the respective computing parameters; identifying patterns, the patterns indicative of a latency-sensitivity of computing workloads; comparing respective values of the computing parameters with the patterns that are indicative of latency-sensitivity of computing workloads; based on the comparing, calculating a match between a particular pattern and values of respective computing parameters; in response to calculating the match, determining that the workload is latency-sensitive, and disabling a link state power management of the IHS; and after disabling the link state power management of the IHS, performing the computing workload.