Abstract: A smart motor includes a motor, a memory, and an electronic processor connected to the motor and the memory. The electronic processor executes a software stack including a hardware layer, an operating layer, and an application layer. The hardware layer provides input/output operations between the motor and the electronic processor. The operating layer provides an intermediary between the hardware layer and the application layer. The application layer executes functions stored in the memory to communicate with and control the hardware layer. Further, the hardware layer, the operating layer, and the application layer selectively control operation of the motor based on one or more signals received from an input device.

Abstract: The invention relates to an apparatus for determining an indicator that is representative of a fluid responsiveness parameter. The indicator is determined based on a fitting of a functional prototype to data values (s0) determined from pulse signals measured over subsequent respiratory cycles. The fitting process is accelerated by a) reducing the number of data values before fitting, b) determining an initial fit parameter value for the functional prototype based on characteristics of the data values and/or a fit parameter value known from a previous fitting, and/or c) carrying out the fitting in several stages, wherein the number of data values used is increased from stage to stage and a fit parameter value determined in a previous stage is used as initial fit parameter value in a current stage. This allows for a faster determination of the fluid responsiveness parameter.

Abstract: A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC).

Abstract: Systems and methods for controlling smart motors. One smart motor system includes a control bus, an input device, and a smart motor communicatively coupled to the input device via the control bus. The smart motor includes an electronic processor configured to receive, from the input device, a command frame indicating an action, perform the action, receive, from the input device, a data request frame requesting a status of the smart motor, and transmit, to the input device and in response to receiving the data request frame, a data frame indicating the status of the smart motor.

Abstract: Method for preparing a sample, wherein the sample is provided as a thin film on a support structure; the temperature of the support structure is adjusted to a value above the dew point temperature of the environment to decrease the film thickness, light is directed at the support structure, an intensity value of the transmitted light is measured, and the support structure is automatically inserted into a liquid cryogen dependent on the measured intensity value. The application further relates to a system comprising a support structure, a temperature-controlled stage for keeping the support structure at a pre-defined temperature, a transfer mechanism for moving the support structure into a container containing a liquid cryogen, a light source, a photodetector for measuring an intensity value of the transmitted light, and a control device for triggering the transfer mechanism dependent on the measured intensity value.

Abstract: Aspects of the present disclosure may address cryptographic methods and systems using redundant encryption and re-keying to provide security in a post-quantum computing environment. A trusted server may initially establish encrypted communications with users, using symmetric key matrices established with the users. The trusted server may be used to establish symmetric key matrices between users and to assist in the users in establishing communications. All of the symmetric keys in a given symmetric key matrix may be used to encrypt plaintext for transmission. Re-keying may be used to generate new symmetric key matrices on a periodic basis or upon initiation by a node or based on a selected secrecy mode. Establishment of symmetric key matrices and re-keying may involve the use of post-quantum key encapsulation mechanisms.

Abstract: A hot runner process controller configured to monitor the status and operation of a hot runner system to autonomously generate information to improve the quality of injection molding process of a hot runner system having an inlet nozzle, one or more manifolds and one or more nozzles with actuator or without actuator, and one or more heating elements, the hot runner process controller is self-operating, and independent from the injection molding machine, includes: one or more sensors located on, in or at the hot runner system to detect the status and/or the operation of the hot runner system, and a processing unit and a memory. The processing unit is connected to the one or more sensors, wherein the memory stores data and program codes.

Abstract: A hot runner process controller configured to monitor the status and operation of a hot runner system to autonomously generate information to improve the quality of injection molding process of a hot runner system having an inlet nozzle, one or more manifolds and one or more nozzles with actuator or without actuator, and one or more heating elements, the hot runner process controller is self-operating, and independent from the injection molding machine, includes: one or more sensors located on, in or at the hot runner system to detect the status and/or the operation of the hot runner system, and a processing unit and a memory. The processing unit is connected to the one or more sensors, wherein the memory stores data and program codes.

Abstract: An optical transformer includes a light source and an array of photovoltaic cells optically coupled to the light source, where at least a portion of the photovoltaic cells are connected in series. An optical connector such as a waveguide or an optical fiber may be disposed between an output of the light source and an input of the array of photovoltaic cells. Configured to generate a high voltage output, the optical transformer may be configured to power a device such as an actuator that provides a tunable displacement as a function of voltage.

Abstract: Systems and methods for controlling smart motors. One smart motor system includes a control bus, an input device, and a smart motor communicatively coupled to the input device via the control bus. The smart motor includes an electronic processor configured to receive, from the input device, a command frame indicating an action, perform the action, receive, from the input device, a data request frame requesting a status of the smart motor, and transmit, to the input device and in response to receiving the data request frame, a data frame indicating the status of the smart motor.

Abstract: A hose reel for coiling a hose includes a frame and a reel assembly rotatably connected to the frame about an axis of rotation. The reel assembly includes a drum assembly having a drum surface configured to receive and support the hose as the drum assembly is rotated about the axis of rotation to coil the hose around the drum surface. The drum assembly includes a hose fitting defining a fluid outlet. The hose fitting is configured to be connected to one end of the hose to fluidly connect the hose to the fluid outlet. The drum assembly defines a recess in the drum surface in which the fluid outlet of the hose fitting is disposed such that at least a portion of the fluid outlet is disposed between the axis of rotation and the drum surface.

Abstract: The invention relates to a preparation system and method for preparing a sample for electron microscopy, the preparation system comprising: a liquid handling system (0) comprising a dispensing head (1), wherein said liquid handling system (0) is configured to aspirate and dispense a volume of a sample via the dispensing head (1), a support structure (2) that is configured to accommodate the sample, a temperature-controlled stage (4) that is configured to keep said support structure (2) at a pre-defined temperature, a first adapter (3) configured to hold said support structure (2), and a transfer mechanism (60) that is configured to be connected to the first adapter (3) holding the support structure (2) and to move said support structure (2) into a container (8) containing a liquid cryogen (80) so that the sample on the support structure (2) contacts the cryogen (80).

Abstract: The present invention is in the field of A roll-to-roll apparatus for processing metal tapes with a ceramic coating. In particular, the present invention relates to a roll-to-roll apparatus for pro-cessing metal tapes with a ceramic coating comprising at least two rolls with fixed axis position, and at least one roll with variable axis position to adjust the tape position and/or tension, wherein the position and the diameter of the rolls are adjusted to touch the metal tape only from one side and to limit the stress on the metal tape at any point such that the metal tape is not stretched by more than 0.15%.

Abstract: The present invention relates to a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer, comprising the measurement of the amounts of specific isoforms of GATA6 and/or NKX2-1 in a sample of said subject. Furthermore, the present invention relates to a composition for use in medicine comprising (an) inhibitor(s) of specific isoforms of GATA6 and/or NKX2-1. Additionally, the present invention relates to a kit for use in a method of assessing whether a subject suffers from cancer or is prone to suffering from cancer, in particular lung cancer.

Abstract: A hot runner process controller configured to monitor the status and operation of a hot runner system to autonomously generate information to improve the quality of injection molding process of a hot runner system having an inlet nozzle, one or more manifolds and one or more nozzles with actuator or without actuator, and one or more heating elements, the hot runner process controller is self-operating, and independent from the injection molding machine, includes: one or more sensors located on, in or at the hot runner system to detect the status and/or the operation of the hot runner system, and a processing unit and a memory. The processing unit is connected to the one or more sensors, wherein the memory stores data and program codes.

Abstract: A hose reel for coiling a hose includes a frame and a reel assembly rotatably connected to the frame about an axis of rotation. The reel assembly includes a drum assembly having a drum surface configured to receive and support the hose as the drum assembly is rotated about the axis of rotation to coil the hose around the drum surface. The drum assembly includes a hose fitting defining a fluid outlet. The hose fitting is configured to be connected to one end of the hose to fluidly connect the hose to the fluid outlet. The drum assembly defines a recess in the drum surface in which the fluid outlet of the hose fitting is disposed such that at least a portion of the fluid outlet is disposed between the axis of rotation and the drum surface.

Abstract: Described herein is an apparatus for quality control of a superconducting tape including (a) at least two rolls contacting the superconducting tape and being suitable for injecting an electric current into the superconducting tape; (b) at least two measuring contacts contacting the superconducting tape and being suitable for measuring an electric voltage along the superconducting tape; and (c) a cooling section suitable for cooling the superconducting tape below its critical temperature, where the at least two rolls and the at least two measuring contacts are located inside the cooling section, and where the cooling section is suitable for keeping the rolls at a first temperature and the measuring contacts at a second temperature, where the first temperature is lower than the second temperature.

Abstract: A system simulator for simulating a wireless system for testing a wireless device under test comprises an uplink signal receiver for receiving an uplink signal generated by the wireless device under test and providing data blocks embedded in the uplink signal, and an uplink signal impairment unit that based on a predetermined probability value sets the data blocks provided by the uplink signal receiver as valid or erroneously received.

Abstract: An optical transformer includes a light source and an array of photovoltaic cells optically coupled to the light source, where at least a portion of the photovoltaic cells are connected in series. An optical connector such as a waveguide or an optical fiber may be disposed between an output of the light source and an input of the array of photovoltaic cells. Configured to generate a high voltage output, the optical transformer may be configured to power a device such as an actuator that provides a tunable displacement as a function of voltage.

Abstract: The present invention is in the field of A roll-to-roll apparatus for processing metal tapes with a ceramic coating. In particular, the present invention relates to a roll-to-roll apparatus for pro-cessing metal tapes with a ceramic coating comprising at least two rolls with fixed axis position, and at least one roll with variable axis position to adjust the tape position and/or tension, wherein the position and the diameter of the rolls are adjusted to touch the metal tape only from one side and to limit the stress on the metal tape at any point such that the metal tape is not stretched by more than 0.15%.