Abstract: The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor.

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.

Abstract: A method and apparatus for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method may include attaching a sensor near an area of a user's body associated with speech production, detecting an electrical signal from the user's nervous system through the sensor, and processing the detected electrical signal to provide communication capability for the user. The processing may include extracting a set of features of the detected electrical signal. The extracted set of features may be compared with a set of prototype features. The set of prototype features may correspond to at least one of multiple response classes. The multiple response classes may include an affirmative response class and a negative response class.

Abstract: Apparatus and methods for managing and upgrading components in an infrastructure are provided. Records relating to components may be retrieved from a database and separated into subsets based on conditions of those components, the types of those components, deterioration models of those components, and/or other factors. Future condition values may be calculated for each subset, and likelihoods of failure of components may be determined for each subset based on those future condition values. The estimated condition values may be used in order to determine an optimal approach to maintaining, refurbishing, and/or replacing the components in the infrastructure. Computational efficiency is increased.

Abstract: The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor.

Abstract: The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor.

Abstract: Systems and methods for continuously planning maintenance of enterprise equipment are provided. Draft forecasts relating to projects in an infrastructure are generated by a computer system. A first user (U1) selects a draft forecast and submits it for approval. The computer system adds the submitted forecast to a submitted scenario. A second user (U2) approves or rejects the submitted forecast for inclusion in a master scenario. The second user may modify the submitted forecast. The system permits continuous planning of projects to maintain an enterprise infrastructure.

Abstract: Apparatus and methods for filtering and displaying different scenarios are provided. Gantt charts illustrating multiple scenarios for performing projects are generated by a computer system. The projects shown in the Gantt charts are filtered by the computer system so that only projects which exhibit differences between the multiple scenarios are displayed. The computer system may display projects with differences that exceed a threshold. Gantt charts may be displayed by computer systems along with risk matrices describing the risks involved in one or more of the projects. Risk matrices plot risk values associated with projects. Computer systems may group projects with similar risk values into bins.

Abstract: Apparatus and methods for managing and upgrading components in an infrastructure are provided. Records relating to components may be retrieved from a database and separated into subsets based on conditions of those components, the types of those components, deterioration models of those components, and/or other factors. Future condition values may be calculated for each subset, and likelihoods of failure of components may be determined for each subset based on those future condition values. The estimated condition values may be used in order to determine an optimal approach to maintaining, refurbishing, and/or replacing the components in the infrastructure. Computational efficiency is increased.

Abstract: A method and apparatus for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method may include attaching a sensor near an area of a user's body associated with speech production, detecting an electrical signal from the user's nervous system through the sensor, and processing the detected electrical signal to provide communication capability for the user. The processing may include extracting a set of features of the detected electrical signal. The extracted set of features may be compared with a set of prototype features. The set of prototype features may correspond to at least one of multiple response classes. The multiple response classes may include an affirmative response class and a negative response class.

Abstract: The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor.

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.

Abstract: This invention relates generally to frame-less luminous displays such as electroluminescent, OLED, and LED displays that are releaseably mounted to a surface using adjustable, removable and/or replaceable adapters. In one embodiment, the invention relates to a thin, frame-less luminous display device which comprises a plurality of thin translucent or transparent layers on which an opaque, graphic layer has been applied and which is illuminated using an electroluminescent light source configured between said transparent or translucent layers. The display device may be further adapted to be releaseably mounted on a surface such as pane of glass using adjustable, removable suction cup type mounting devices.

Abstract: The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor.

Abstract: The invention provides a frameless, lightweight, bright light, portable display in the form of electroluminescence with multiple reversible mounting suction cups. The luminous unit comes in various sizes of which most are round in shape. Each unit contains a power plug, inverter, and the electroluminescent panel. However, each unit also includes a minimum of 3 suction cup extensions allowing for the unit to be reversible. This unit is able to be mounted on the inside of a window or the outside of a window/hard slick surface with the light facing same direction no matter which side of the glass it is mounted thereon.

Abstract: Provided herein are tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are generally located on or within the region of the cytokine receptor ligand that faces away from a receptor complex while the ligand is bound to the receptor. Also provide herein are fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO; methods for treating or preventing a disease or disorder using tissue protective peptides; and methods for enhancing excitable tissue function using tissue protective peptides.

Abstract: Provided herein are tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are generally located on or within the region of the cytokine receptor ligand that faces away from a receptor complex while the ligand is bound to the receptor. Also provide herein are fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO; methods for treating or preventing a disease or disorder using tissue protective peptides; and methods for enhancing excitable tissue function using tissue protective peptides.

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.

Abstract: The invention provides a frameless, lightweight, bright light, portable display in the form of electroluminescence with multiple reversible mounting suction cups. The luminous unit comes in various sizes of which most are round in shape. Each unit contains a power plug, inverter, and the electroluminescent panel. However, each unit also includes a minimum of 3 suction cup extensions allowing for the unit to be reversible. This unit is able to be mounted on the inside of a window or the outside of a window/hard slick surface with the light facing same direction no matter which side of the glass it is mounted thereon.

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.