Patents by Inventor Thomas A. Craig

Thomas A. Craig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Equipment protecting enclosures
    Patent number: 10589251
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in a vault in which the equipment is protected from radiation and hazardous gases by equipment enclosures. The equipment enclosures may be purged with gas.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: March 17, 2020
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medhoff, Thomas Craig Masterman, Robert Paradis
  • TREATING BIOMASS
    Publication number: 20200075288
    Abstract: Methods and systems are described for processing cellulosic and lignocellulosic materials and useful intermediates and products, such as energy and fuels. For example, irradiating methods and systems are described to aid in the processing of the cellulosic and lignocellulosic materials. The electron beam accelerator has multiple windows foils and these foils are cooled with cooling gas. In one configuration a secondary foil is integral to the electron beam accelerator and in another configuration the secondary foil is part of the enclosure for the biomass conveying system.
    Type: Application
    Filed: November 7, 2019
    Publication date: March 5, 2020
    Inventors: Marshall MEDOFF, Anthony PETERS, Thomas Craig MASTERMAN, Robert PARADIS, Kenny Kin-Chui IP
  • PROCESSING BIOMASS
    Publication number: 20200070120
    Abstract: Methods and systems are described for processing cellulosic and lignocellulosic materials into useful intermediates and products, such as energy and fuels. For example, conveying systems and methods, such as highly efficient vibratory conveyors, are described for the processing of the cellulosic and lignocellulosic materials.
    Type: Application
    Filed: October 23, 2019
    Publication date: March 5, 2020
    Inventors: Marshall MEDOFF, Thomas Craig MASTERMAN, Robert PARADIS
  • ENCLOSURES FOR TREATING MATERIALS
    Publication number: 20200038811
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in two or more vaults that can share a common wall.
    Type: Application
    Filed: September 28, 2019
    Publication date: February 6, 2020
    Inventors: Marshall MEDOFF, Thomas Craig MASTERMAN, ROBERT PARADIS
  • Enclosures for treating materials
    Patent number: 10549241
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in two or more vaults that can share a common wall.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: February 4, 2020
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Robert Paradis
  • Upgrading process streams
    Patent number: 10543460
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. Systems, methods and equipment are described for upgrading process streams using electrodialysis or electrodialysis reversal.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: January 28, 2020
    Assignee: XYLECO, INC.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Maia Stapleton Mukherjee, Christopher Cooper
  • Chimeric Antigen Receptors with BCMA Specificity and Uses Thereof
    Publication number: 20200023010
    Abstract: B-cell maturation antigen (BCMA) is expressed on malignant plasma cells. The present invention provides BCMA-specific chimeric antigen receptors and cells expressing such chimeric antigen receptors. In certain embodiments, engineered cells expressing the chimeric antigen receptors of the present invention are capable of inhibiting the growth of tumors expressing BCMA. The engineered cells of the invention are useful for the treatment of diseases and disorders in which an upregulated or induced BCMA-targeted immune response is desired and/or therapeutically beneficial. For example, engineered cells expressing the BCMA-specific chimeric antigen receptors of the invention are useful for the treatment of various cancers, including multiple myeloma.
    Type: Application
    Filed: July 18, 2019
    Publication date: January 23, 2020
    Inventors: David DiLillo, Frank Delfino, Kevin Bray, Thomas Craig Meagher, Jessica Kirshner, Olga Sineshchekova
  • PRODUCTION OF PRODUCTS FROM BIOMASS
    Publication number: 20200017894
    Abstract: The processes disclosed herein include saccharifying cellulosic and/or lignocellulosic biomass and fermenting the sugars to produce a sugar alcohol.
    Type: Application
    Filed: September 12, 2019
    Publication date: January 16, 2020
    Inventors: Marshall MEDOFF, Thomas Craig MASTERMAN, Jaewoong MOON, Aiichiro YOSHIDA
  • CONVERSION OF BIOMASS
    Publication number: 20200010440
    Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert feedstock materials to a sugar solution, especially, xylose, which can then be chemically converted to furfural and furfural-derived products.
    Type: Application
    Filed: September 18, 2019
    Publication date: January 9, 2020
    Inventors: Marshall Medoff, Thomas Craig Masterman, Christopher Cooper, Jihan Khan
  • Processing materials
    Patent number: 10518220
    Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, novel systems, methods and equipment for conveying and/or cooling treated biomass are described.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: December 31, 2019
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Robert Paradis
  • Processing biomass
    Patent number: 10519180
    Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce a product or intermediate, e.g., energy, a food, a fuel, or a material.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: December 31, 2019
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman
  • Treating biomass
    Patent number: 10510510
    Abstract: Methods and systems are described for processing cellulosic and lignocellulosic materials and useful intermediates and products, such as energy and fuels. For example, irradiating methods and systems are described to aid in the processing of the cellulosic and lignocellulosic materials. The electron beam accelerator has multiple windows foils and these foils are cooled with cooling gas. In one configuration a secondary foil is integral to the electron beam accelerator and in another configuration the secondary foil is part of the enclosure for the biomass conveying system.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: December 17, 2019
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Anthony Peters, Thomas Craig Masterman, Robert Paradis, Kenny Kin-Chui Ip
  • Processing biomass
    Patent number: 10508293
    Abstract: Provided herein are methods of increasing the efficiency of biomass saccharification. In particular, the methods include ways of avoiding feedback inhibition of enzymatic reactions during the production of useful products. The methods also include saccharifying recalcitrance-reduced lignocellulosic biomass and adding an isomerization agent to the saccharified biomass. The saccharified biomass can be further converted into products by a microorganism.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: December 17, 2019
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Michael W. Finn
  • Processing biomass to obtain hydroxylcarboxylic acids
    Patent number: 10501761
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as hydroxy-carboxylic acids and hydroxy-carboxylic acid derivatives. A method includes treating a reduced recalcitrance lignocellulosic or cellulosic material with one or more enzymes and/or organisms (such as lactobacillus, Pediococcus, Rhizopus, Enterococcus) to produce an alpha, beta, gamma and/or delta hydroxycarboxylic acid (such as lactic acid, glycolic acid); and converting the alpha, beta, gamma and/or delta hydroxy-carboxylic acid to the product (such as esters, polymers, and copolymers).
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: December 10, 2019
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Andrew Papoulis, Jaewoong Moon, Jihan Khan, Robert Paradis
  • Processing biomass
    Patent number: 10500561
    Abstract: Methods and systems are described for processing cellulosic and lignocellulosic materials into useful intermediates and products, such as energy and fuels. For example, conveying systems and methods, such as highly efficient vibratory conveyors, are described for the processing of the cellulosic and lignocellulosic materials.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: December 10, 2019
    Assignee: XYLECO, INC.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Robert Paradis
  • Conversion of biomass
    Patent number: 10457656
    Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert feedstock materials to a sugar solution, especially, xylose, which can then be chemically converted to furfural and furfural-derived products.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: October 29, 2019
    Assignee: XYLECO, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Christopher Cooper, Jihan Khan
  • PROCESSING HYDROXY-CARBOXYLIC ACIDS TO POLYMERS
    Publication number: 20190322800
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as aliphatic hydroxy-carboxylic acid and hydroxyl-carboxylic acid derivatives. These aliphatic hydroxy-carboxylic acids are, in turn, polymerized. The polymerization is carried out using a thin film evaporator or a thin film polymerization/devolatilization device. Conversion of lactic acid to poly lactic acid is an especially useful product to this process.
    Type: Application
    Filed: November 16, 2018
    Publication date: October 24, 2019
    Applicant: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Robert Paradis
  • SOLUBILIZED ENZYME AND USES THEREOF
    Publication number: 20190316108
    Abstract: The present invention relates to mixtures comprising a polypeptide or a plurality of polypeptides having biomass-degrading activity that is solubilized from an inclusion body, and retaining biomass-degrading activity, and methods for producing and using the same. The invention described herein provides methods for increasing the yield of recombinant protein with biomass-degrading activity that can be isolated from host cells.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 17, 2019
    Inventors: Marshall Medoff, Natasha Kreder, James Lynch, Sean Landry, Aiichiro Yoshida, Desiree Pangilinan, Thomas Craig Masterman
  • RECONFIGURABLE PROCESSING ENCLOSURES
    Publication number: 20190316294
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) or other materials are processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in a vault in which the walls and optionally the ceiling include discrete units. Such vaults are re-configurable.
    Type: Application
    Filed: June 3, 2019
    Publication date: October 17, 2019
    Inventors: Marshall MEDOFF, Thomas Craig MASTERMAN, Robert PARADIS
  • Support structure detection
    Patent number: 10444012
    Abstract: While typically-collected diameter data contains information for detecting some garter springs, many garter springs may not be detected without processing the diameter data. Responsively, a method for processing the diameter data to detect the garter springs has been developed. In particular, the processing involves fitting of the diameter data to a shape, determining residual errors and using the residual errors to locate garter springs.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: October 15, 2019
    Inventors: Stuart Thomas Craig, Kenneth Robert Chaplin