Patents by Inventor Thomas A. Haby

Thomas A. Haby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and formulation containing epothilones and analogs thereof
    Patent number: 8871227
    Abstract: A process for formulating certain epothilones and analogs thereof for parenteral administration is provided wherein the pH of the formulation for administration can be controlled to enhance the stability and thus, potency of the epothilone, or analog thereof.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: October 28, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Thomas A. Haby, Uday S. Gogate, Vijay H. Naringrekar
  • PROCESS AND FORMULATION CONTAINING EPOTHILONES AND ANALOGS THEREOF
    Publication number: 20100016385
    Abstract: A process for formulating certain epothilones and analogs thereof for parenteral administration is provided wherein the pH of the formulation for administration can be controlled to enhance the stability and thus, potency of the epothilone, or analog thereof.
    Type: Application
    Filed: September 11, 2009
    Publication date: January 21, 2010
    Inventors: Thomas A. Haby, Uday S. Gogate, Vijay H. Naringrekar
  • Nanoparticle dispersion containing lactam compound
    Publication number: 20090004277
    Abstract: Disclosed is a nanoparticle dispersion comprising nanoparticles dispersed in an aqueous medium in the presence of at least one stabilizer. The nanoparticles comprise at least lactam compound of formula I: wherein R1, R2, R3, R4, R5, R6, R7, and Q are defined herein. A method is provided of the parenteral administration of the nanoparticle dispersion as a treatment for cancer or another proliferative disease. Also, a solid nanoparticulate composition comprising the nanoparticles of the lactam compound, and a method of administration are disclosed.
    Type: Application
    Filed: May 16, 2005
    Publication date: January 1, 2009
    Inventors: Miriam K. Franchini, Thomas A. Haby, Elaine Liversidge
  • Pharmaceutical compositions and methods of using C-21 modified epothilone derivatives
    Patent number: 7053069
    Abstract: Pharmaceutical compositions containing C-21 modified epothilone derivatives, methods for their preparation and dosing regimen for administration of these epothilone compounds are provided. The compositions are stable and readily prepared for administration by dissolution in aqueous vehicles suitable for intravenous administration. A process for formulating C-21 modified epothilone derivatives for oral and parenteral administration is disclosed.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: May 30, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Francis Y. F. Lee, Thomas A. Haby, Vijay H. Naringrekar, Krishnaswamy S. Raghavan, Miriam K. Franchini
  • Process and formulation containing epothilones and analogs thereof
    Publication number: 20050171167
    Abstract: A process for formulating certain epothilones and analogs thereof for parenteral administration is provided wherein the pH of the formulation for administration can be controlled to enhance the stability and thus, potency of the epothilone, or analog thereof.
    Type: Application
    Filed: November 3, 2004
    Publication date: August 4, 2005
    Inventors: Thomas Haby, Uday Gogate, Vijay Naringrekar
  • Pharmaceutical compositions and methods of using C-21 modified epothilone derivatives
    Publication number: 20040053978
    Abstract: Pharmaceutical compositions containing C-21 modified epothilone derivatives, methods for their preparation and dosing regimen for administration of these epothilone compounds are provided. The compositions are stable and readily prepared for administration by dissolution in aqueous vehicles suitable for intravenous administration. A process for formulating C-21 modified epothilone derivatives for oral and parenteral administration is disclosed.
    Type: Application
    Filed: May 13, 2003
    Publication date: March 18, 2004
    Inventors: Francis Y. F. Lee, Thomas A. Haby, Vijay H. Naringrekar, Krishnaswamy S. Raghavan, Miriam K. Franchini