Patents by Inventor Thomas A. Knowles
Thomas A. Knowles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220287603Abstract: Apparatus, systems, and methods are provided that generate in vivo maps of oxygenation measurements of biological tissue. These may include surgical instruments and stand-alone imaging systems with incorporated oxygen sensing capability. Oxygenation maps can be determined via fluorescent or phosphorescent lifetime imaging of an injectable probe with an oxygen-dependent optical response. Probe configuration and methods and apparatus of injecting the probe into the tissue are provided. Methods and apparatus for temperature compensation of temperature-dependent lifetime measurements are provided to improve oxygenation measurement accuracy. Oxygen maps may be registered with visible light images to assist in assessing tissue viability or localize anomalies in the tissue.Type: ApplicationFiled: October 21, 2021Publication date: September 15, 2022Applicant: SURGISENSE CORPORATIONInventors: Jason Matthew Zand, Gregory Scott Fischer, Justin Thomas Knowles
-
Publication number: 20190282146Abstract: Apparatus, systems, and methods are provided that generate in vivo maps of oxygenation measurements of biological tissue. These may include surgical instruments and stand-alone imaging systems with incorporated oxygen sensing capability. Oxygenation maps can be determined via fluorescent or phosphorescent lifetime imaging of an injectable probe with an oxygen-dependent optical response. Probe configuration and methods and apparatus of injecting the probe into the tissue are provided. Methods and apparatus for temperature compensation of temperature-dependent lifetime measurements are provided to improve oxygenation measurement accuracy. Oxygen maps may be registered with visible light images to assist in assessing tissue viability or localize anomalies in the tissue.Type: ApplicationFiled: October 19, 2018Publication date: September 19, 2019Applicant: SURGISENSE CORPORATIONInventors: Jason Matthew Zand, Gregory Scott Fischer, Justin Thomas Knowles
-
Patent number: 9935998Abstract: A wireless apparatus and system automatically processes digital “messages” to a remote system at a predefined destination address. Initial transmission occurs via a wireless network, and the apparatus process allows the simultaneous capture of new messages while transmissions are occurring. The destination address may correspond to an e-mail account, or may correspond to a remote server from which the message can be efficiently processed and/or further distributed. In the latter case, data packaged with the digital message is used to control processing of the message at the server, based on a combination of pre-defined system and user options. Secured Internet access to the server allows flexible user access to system parameters for configuration of message handling and distribution options, including the option to build named distribution lists that are downloaded to the wireless apparatus.Type: GrantFiled: August 10, 2017Date of Patent: April 3, 2018Assignee: FO2GO LLCInventor: Andrew Thomas Knowles
-
Publication number: 20170339212Abstract: A wireless apparatus and system automatically processes digital “messages” to a remote system at a predefined destination address. Initial transmission occurs via a wireless network, and the apparatus process allows the simultaneous capture of new messages while transmissions are occurring. The destination address may correspond to an e-mail account, or may correspond to a remote server from which the message can be efficiently processed and/or further distributed. In the latter case, data packaged with the digital message is used to control processing of the message at the server, based on a combination of pre-defined system and user options. Secured Internet access to the server allows flexible user access to system parameters for configuration of message handling and distribution options, including the option to build named distribution lists that are downloaded to the wireless apparatus.Type: ApplicationFiled: August 10, 2017Publication date: November 23, 2017Inventor: Andrew Thomas Knowles
-
Patent number: 9687634Abstract: An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.Type: GrantFiled: August 16, 2013Date of Patent: June 27, 2017Assignee: Boston Scientific Scimed, Inc.Inventors: Adam D. Grovender, Benjamin P. Gundale, Thomas Knowles, Roger W. McGowan, Charles Rundquist, Chuanjing Xu, Todd Rowe
-
Publication number: 20150282749Abstract: Apparatus, systems, and methods are provided that generate in vivo maps of oxygenation measurements of biological tissue. These may include surgical instruments and stand-alone imaging systems with incorporated oxygen sensing capability. Oxygenation maps can be determined via fluorescent or phosphorescent lifetime imaging of an injectable probe with an oxygen-dependent optical response. Probe configuration and methods and apparatus of injecting the probe into the tissue are provided. Methods and apparatus for temperature compensation of temperature-dependent lifetime measurements are provided to improve oxygenation measurement accuracy. Oxygen maps may be registered with visible light images to assist in assessing tissue viability or localize anomalies in the tissue.Type: ApplicationFiled: April 6, 2015Publication date: October 8, 2015Applicant: SURGISENSE CORPORATIONInventors: Jason Matthew Zand, Gregory Scott Fischer, Justin Thomas Knowles
-
Publication number: 20140360453Abstract: A valve guide insert for lining and relining a valve guide bore in an internal combustion engine includes a one-piece, thin-walled, cylindrically-shaped metallic tube made from reformable bearing material having first and second ends and an intermediate portion. An inwardly tapered portion is disposed at the first end, wherein an end diameter of the inwardly tapered portion is less than an outer diameter of a valve guide bore, and wherein the outer diameter of the intermediate section is greater than an inner diameter of a valve guide bore. A longitudinal slit is included having a stepped portion along a length of the longitudinal slit. An interference portion is disposed proximate the second end, wherein the interference portion is configured to substantially secure the valve guide insert within a valve guide bore.Type: ApplicationFiled: May 15, 2014Publication date: December 11, 2014Applicant: K-Line Industries, Inc.Inventors: Thomas Knowles, II, Dwain Kamphuis
-
Publication number: 20130331782Abstract: An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.Type: ApplicationFiled: August 16, 2013Publication date: December 12, 2013Applicant: Boston Scientific Scimed, Inc.Inventors: Adam D. Grovender, Benjamin P. Gundale, Thomas Knowles, Roger W. McGowan, Charles Rundquist, Chuanjing Xu, Todd Rowe
-
Patent number: 8512282Abstract: An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.Type: GrantFiled: November 14, 2011Date of Patent: August 20, 2013Assignee: Boston Scientific Scimed, Inc.Inventors: Adam D. Grovender, Benjamin Grundale, Thomas Knowles, Roger W. McGowan, Todd Rowe, Charles Rundquist, Chuanjing Xu
-
Publication number: 20120059336Abstract: An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.Type: ApplicationFiled: November 14, 2011Publication date: March 8, 2012Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Adam D. Grovender, Benjamin Gundale, Thomas Knowles, Roger W. McGowan, Todd Rowe, Charles Rundquist, Chuanjing Xu
-
Patent number: 8057430Abstract: An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.Type: GrantFiled: February 20, 2009Date of Patent: November 15, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Adam D. Grovender, Benjamin Gundale, Thomas Knowles, Roger W. McGowan, Todd Rowe, Charles Rundquist, Chuanjing Xu
-
Patent number: 7934204Abstract: A partitioning technique utilized by a translator to divide the subject code space into regions, referred to hereafter as partitions, where each partition contains a distinct set of basic blocks of subject code and corresponding target code. The partitioning technique divides the translator's representation of subject code and subject code translations into non-overlapping regions of subject memory. In this manner, when the subject program modifies subject code, only those partitions actually affected by the self-modifying code need be discarded and all translations in unaffected partitions can be kept. This partitioning technique is advantageous in limiting the amount of target code that must be retranslated in response to self-modifying code operation. In another process, the partitioning technique allows multithreaded subject programs that also involve self-modifying code to perform code modification in a thread-safe manner.Type: GrantFiled: March 17, 2004Date of Patent: April 26, 2011Assignee: International Business Machines CorporationInventors: Alex Brown, Paul Thomas Knowles, Geraint North
-
Publication number: 20100217234Abstract: An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.Type: ApplicationFiled: February 20, 2009Publication date: August 26, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Adam D. Grovender, Benjamin Gundale, Thomas Knowles, Roger W. McGowan, Todd Rowe, Charles Rundquist, Chuanjing Xu
-
Patent number: 7685579Abstract: An adjustable precision exception handling technique is providing for handling exceptions encountered during translation of subject code to target code at varying levels of precision, depending upon the particular type of exception encountered. As an exception signal is detected by the translator, the state of the subject processor is captured at a precision determined to be sufficient for the detected exception.Type: GrantFiled: December 2, 2003Date of Patent: March 23, 2010Assignee: International Business Machines CorporationInventor: Paul Thomas Knowles
-
Publication number: 20080263342Abstract: Described is method and apparatus for handling exception signals in combination particularly with the dynamic conversion of binary code executable by a one computing platform into binary code executed instead by another computing platform. An exception handling unit selectively handles some exception signals with respect to a target state and handles others with respect to a subject state derived from the target state. Signal handling sub-units are arranged to process the exception signal with respect to the target state and output a request either to return to execution or to pass on the exception signal. A delivery path selection unit is arranged to determine a delivery path of the exception signal to a selected group of the plurality of signal handling sub-units. A signal control unit is arranged to deliver the exception signal in turn to each of the selected group of signal handling sub-units.Type: ApplicationFiled: June 4, 2007Publication date: October 23, 2008Applicant: Transitive LimitedInventors: Paul Thomas Knowles, Kit Man Wan
-
Publication number: 20050197848Abstract: The system supports special needs customer at an airport. A controller processes request, flight and personnel data, generates assignments, and distributes messages. Workstations register available personnel, import/export customer requests and flight information, edit additional customer and flight data, and authorize or overwrite dispatch decisions. Handheld devices provide customer registration, service recording and location registration, and communicate service instructions and activity planning. The controller receives and analyzes data based upon a set of conditions that determine the status of any service request, the location where service is needed, the type of assistance needed, its priority, and the destination of the service. Upon arrival at the destination, or, based upon a set of predetermined conditions, the controller analyzes current conditions, determines the next set of requests and assignments, and provides information needed to support the next assignments.Type: ApplicationFiled: April 23, 2004Publication date: September 8, 2005Inventors: Y. Chou, Tom Farmakis, Thomas Knowles, Al Johnson
-
Publication number: 20040201486Abstract: A solid state crossing controller for a railroad crossing signal system with two independent outputs for controlling illumination of lamps in the signal system share a common neutral or return wire, with sensing of a common neutral or return line shared by the two independent outputs to determine any loss of the neutral line. When a failure has been detected in the neutral line, the controller modifies the voltages for the lamps in the signaling system for better illumination of the lamps during the failure condition, such as to the highest voltage available from a battery in the system. Upon detection of the failure in the neutral line, the controller may provide a call or message that there is a failure in the system that is in need of repair. If the failure in the neutral line is intermittent, the controller will resume normal operation after that train, has cleared the crossing. However, a call or message that a failure has occurred in the neutral line is provided.Type: ApplicationFiled: April 10, 2003Publication date: October 14, 2004Inventors: Thomas Knowles, Rakesh Malhotra, Hung Pham, John Sharkey
-
Patent number: 6665868Abstract: A method, system, and computer program product for optimizing recognition of presentation space data. Presentation space data is sent from a legacy host application to a workstation. A workstation application monitors arrival of multiple predetermined presentation space definitions, and invokes an appropriate target object to process each recognized presentation space of interest. Prioritization techniques are used to optimize the recognition process, whereby higher priority definitions are processed first. A time of day heuristic is defined, which influences priority of presentation space recognition according to the time of day in which specific presentation space data typically arrives at the user's workstation. Priority pools may be used to provide a desired granularity of priority. Priority may be learned dynamically by the implementation, and may be initialized explicitly (or defaulted). Priority of a definition may be demoted if an inactivity timer expires.Type: GrantFiled: March 21, 2000Date of Patent: December 16, 2003Assignee: International Business Machines CorporationInventors: Gregory Thomas Knowles, Bradley Thomas Marchesseault, James Merwin Mathewson, II, Brian Thomas Webb
-
Patent number: 6519605Abstract: A technique, system, and computer program for run-time translation of procedurally-oriented Emulator High Level Language Application Programming Interface (EHLLAPI) calls into object-based host access calls (such as those provided with IBM's Host Access Control Library or the Open Host Interface Objects under development by the IETF), without requiring changes to the workstation EHLLAPI applications. This translation, in addition to generating the appropriate method invocation, reconciles the operational differences between EHLLAPI's sequential function call model and the event-driven approach used in the object-oriented model.Type: GrantFiled: April 27, 1999Date of Patent: February 11, 2003Assignee: International Business Machines CorporationInventors: David Blair Gilgen, Gregory Thomas Knowles, Scott Matthew Quint, Brian Thomas Webb
-
Patent number: 6014702Abstract: A method and apparatus for developing persistent, single implementation host access applications deployable across multiple platforms. The interaction between host and clients is accomplished directly without platform-specific server function and with data-stream, versus screen, manipulation of host information.Type: GrantFiled: June 4, 1997Date of Patent: January 11, 2000Assignee: International Business Machines CorporationInventors: Thomas F. King, Gregory Thomas Knowles, Raymond Steven Rittenhouse, Yih-Shin Tan