Abstract: An integrated information system is provided for a plant with interactive processes running in functional equipment subsets, such as a nuclear power generation plant. Sensors are operatively coupled to monitor processes and equipment in the plant, collecting sample data for assessing operational conditions and for predicting maintenance requirements based on loading of the equipment. One or more processors access the sample data and compares present conditions to diagnostic specifications, technical specifications and historical data stored in memory and indexed to equipment subsets and functional operating groups. The processor(s) generate prioritized reports to alert users to potential operational and/or maintenance problems. In addition to the prioritized reports, the processor accesses and outputs to the users reports of the diagnostic and technical specifications applicable to the process parameters exhibiting the potential problems.