Patents by Inventor Thomas A. Lessen

Thomas A. Lessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Patent number: 9321739
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: April 26, 2016
    Assignee: MICRODOSE THERAPEUTX, INC.
    Inventors: David J. Rys, Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Daniel C. Pevear, Thomas A. Lessen, Torsten Herbertz
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Patent number: 8962667
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: February 24, 2015
    Assignee: Microdose Therapeutix, Inc.
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laquerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES
    Publication number: 20140363395
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Application
    Filed: July 24, 2014
    Publication date: December 11, 2014
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laquerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Patent number: 8846735
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: September 30, 2014
    Assignee: Microdose Therapeutx, Inc.
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laguerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES
    Publication number: 20140072532
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Application
    Filed: October 11, 2013
    Publication date: March 13, 2014
    Applicant: MICRODOSE THERAPEUTX, INC.
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laguerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Patent number: 8575205
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: November 5, 2013
    Assignee: Microdose Therapeutx, Inc.
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laguerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES
    Publication number: 20120183498
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Application
    Filed: March 22, 2012
    Publication date: July 19, 2012
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laguerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Patent number: 8202896
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: June 19, 2012
    Assignee: Microdose Therapeutx, Inc.
    Inventors: Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Sylvie Laguerre, Daniel C. Pevear, Thomas A. Lessen, David J. Rys
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Patent number: 8119672
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: February 21, 2012
    Assignee: Microdose Therapeutx, Inc.
    Inventors: David J. Rys, Theodore J. Nitz, Janet A Gaboury, Christopher J. Burns, Daniel C. Pevear, Thomas A. Lessen, Torsten Herbertz
  • COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES
    Publication number: 20110305666
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.
    Type: Application
    Filed: August 23, 2011
    Publication date: December 15, 2011
    Inventors: David J. Rys, Theodore J. Nitz, Janet A. Gaboury, Christopher J. Burns, Daniel C. Pevear, Thomas A. Lessen, Torsten Herbertz
  • BETA-LACTAMASE INHIBITORS
    Publication number: 20100292185
    Abstract: Disclosed herein are ?-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising ?-aminoboronic acids and methods of use thereof.
    Type: Application
    Filed: May 10, 2010
    Publication date: November 18, 2010
    Inventors: Christopher J. Burns, Rajesh Goswami, Randy W. Jackson, Thomas Lessen, Weiping Li, Daniel Pevear, Pavan Kumar Tirunahari, Hongyu Xu
  • Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases
    Patent number: 7666863
    Abstract: The present invention relates to benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: February 23, 2010
    Assignees: ViroPharma Incorporated, WYETH
    Inventors: Ashis K. Saha, Christopher J Burns, Alfred M. Del Vecchio, Thomas R. Bailey, Jason A. Reinhardt, Bheemashankar A. Kulkarni, Thomas H. Faitg, Hao Feng, Susan R. Rippin, Charles W. Blackledge, David J. Rys, Thomas A. Lessen, John Swestock, Yijun Deng, Theodore J. Nitz
  • BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES
    Publication number: 20090281336
    Abstract: The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.
    Type: Application
    Filed: July 9, 2009
    Publication date: November 12, 2009
    Inventors: Ashis K. Saha, Christopher J. Burns, Alfred M. Del Vecchio, Thomas R. Bailey, Jason A. Reinhardt, Bheemashankar A. Kulkarni, Thomas H. Faitg, Hao Feng, Susan R. Rippin, Charles W. Blackledge, David J. Rys, Thomas A. Lessen, John Swestock, Yijun Deng, Theodore J. Nitz
  • BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES
    Publication number: 20070231318
    Abstract: The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 4, 2007
    Inventors: Ashis Saha, Christopher Burns, Alfred Del Vecchio, Thomas Bailey, Jason Reinhardt, Bheemashankar Kulkarni, Thomas Faitg, Hao Feng, Susan Rippin, Charles Blackledge, David Rys, Thomas Lessen, John Swestock, Yijum Deng, Theodore Nitz
  • Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases
    Patent number: 7265152
    Abstract: The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: September 4, 2007
    Assignees: ViroPharma Incorporated, Wyeth
    Inventors: Ashis K. Saha, Christopher J Burns, Alfred M. Del Vecchio, Thomas R. Bailey, Jason A. Reinhardt, Bheemashankar A. Kulkarni, Thomas H. Faitg, Hao Feng, Susan R. Rippin, Charles W. Blackledge, David J. Rys, Thomas A. Lessen, John Swestock, Yijun Deng, Theodore J. Nitz
  • FUNGICIDAL CARBOXAMIDES
    Publication number: 20060178425
    Abstract: Compounds of Formula I are disclosed which are useful as fungicides wherein X is —O—, —CH(R11)— or ?C(R11)—; R1 is H or C1-C2 alkyl; R2 is H; C1-C6 alkyl; C3-C6 cycloalkyl; or phenyl optionally substituted with halogen, cyano, C1-C2 alkyl or C1-C2 alkoxy; and R3—R11 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound of Formula I.
    Type: Application
    Filed: March 2, 2001
    Publication date: August 10, 2006
    Inventors: Gregory Basarab, Douglas Jordan, Thomas Lessen, Stephen Hansen
  • FUNGICIDAL CARBOXAMIDES
    Publication number: 20060025472
    Abstract: Compounds of Formula I are disclosed which are useful as fungicides wherein Q is X is —O—, —CH(R11)— or ?C(R11)—; R1 is H or C1-C2 alkyl; R2 is H; C1-C6 alkyl; C3-C6 cycloalkyl; or phenyl optionally substituted with halogen, cyano, C1-C2 alkyl or C1-C2 alkoxy; and R3-R11 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound of Formula I.
    Type: Application
    Filed: March 2, 2001
    Publication date: February 2, 2006
    Inventors: Gregory Basarab, Douglas Jordan, Thomas Lessen, Stephen Hansen
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Publication number: 20050288345
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.
    Type: Application
    Filed: August 11, 2003
    Publication date: December 29, 2005
    Inventors: David Rys, Theodore Nitz, Janet Gaboury, Christopher Burns, Daniel Pevear, Thomas Lessen, Torsten Herbertz
  • Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
    Publication number: 20050288344
    Abstract: Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.
    Type: Application
    Filed: August 11, 2003
    Publication date: December 29, 2005
    Inventors: Theodore Nitz, Janet Gaboury, Christopher Burns, Sylvia Laquerre, Daniel Pevear, Thomas Lessen, David Rys
  • Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases
    Publication number: 20040162318
    Abstract: The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.
    Type: Application
    Filed: October 31, 2003
    Publication date: August 19, 2004
    Inventors: Ashis K. Saha, Christopher J. Burns, Alfred M. Del Vecchio, Thomas R. Bailey, Jason A. Reinhardt, Bheemashankar A. Kulkarni, Thomas H. Faitg, Hao Feng, Susan R. Rippin, Charles W. Blackledge, David J. Rys, Thomas A. Lessen, John Swestock, Yijun Deng, Theodore J. Nitz