Patents by Inventor Thomas A. Lindner

Thomas A. Lindner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230112012
    Abstract: The present invention relates to a compound of formula (I), a pharmaceutical composition comprising or consisting of said compound, a kit comprising or consisting of said compound or pharmaceutical composition and use of the compound or pharmaceutical composition in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP).
    Type: Application
    Filed: July 1, 2022
    Publication date: April 13, 2023
    Inventors: Uwe HABERKORN, Anastasia LOKTEV, Thomas LINDNER, Walter MIER, Frederik GIESEL, Clemens KRATOCHWIL
  • Publication number: 20230073687
    Abstract: A roof module for a motor vehicle, in particular for a passenger car, the roof module comprising a roof skin disposed on a roof substructure and a sensor system comprising at least one sensor module having at least one environment sensor for detecting the vehicle environment. The roof skin covers an air-conditioning mechanism having a thermal channel arrangement via which a cooling and/or heating fluid flows to the sensor module and/or an electrical feature of the roof module.
    Type: Application
    Filed: February 3, 2021
    Publication date: March 9, 2023
    Inventors: Thomas LINDNER, Andreas STRAßER, Michael HUELSEN
  • Publication number: 20220324898
    Abstract: In particular, the present invention relates to a PSMA binding ligand comprising an oligosaccharide building block which comprises a bond being cleavable by alpha-amylase. Typically, this PSMA binding ligand further comprises a PSMA binding motif Q and a chelator residue A, wherein the PSMA binding motif Q and the chelator residue A are preferably linked via at least one linker LAQ comprising the oligosaccharide building block, the PSMA binding ligand thus preferably having the structure (I) A-LAQ-Q or a pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: February 14, 2020
    Publication date: October 13, 2022
    Inventors: Matthias Eder, klaus Kopka, Martin Schäfer, Ulrike Bauder-Wuest, Uwe Haberkrn, Hans-Christian Kliem, Walter Mier, Thomas Lindner
  • Publication number: 20220289006
    Abstract: A roof module for connection to a motor vehicle having a transparent solid roof portion, which forms a see-through roof area and which is immobile relative to the vehicle body when the roof module is in the installed position, and/or a roof opening system having a mobile lid element, by means of which a roof opening can be opened or closed at will, and a closed roof skin, which forms the see-through roof area and/or is adjacent to the roof opening and forms a roof cover outside of the see-through roof area and/or the roof opening. At least one sensor module can be provided having at least one environment sensor for detecting a vehicle environment and is disposed outside of the see-through roof area and/or the roof opening and is covered by the roof skin.
    Type: Application
    Filed: August 11, 2020
    Publication date: September 15, 2022
    Inventors: Michael HUELSEN, Dirk LEGLER, Michael DEPPE, Johannes THANNHEIMER, Thomas RUDOLPH, Thomas LINDNER
  • Publication number: 20220285831
    Abstract: A roof module for forming at least a part of the vehicle roof on a motor vehicle, the roof module having a panel component whose outer surface at least partially forms the roof skin of the vehicle roof, the roof module having at least one environment sensor configured to send and/or receive electromagnetic signals for detecting the vehicle surroundings. The roof module has at least one antenna module configured to receive and/or send radio signals.
    Type: Application
    Filed: August 14, 2020
    Publication date: September 8, 2022
    Inventors: Michael HUELSEN, Oliver HEISEL, Andreas STRASSER, Thomas LINDNER, Max HUBER
  • Publication number: 20220266917
    Abstract: A roof module of a motor vehicle having a roof substructure, a roof cladding, which forms an outer visible surface of the roof module, and at least one sensor module having an environment sensor for sensing a vehicle environment, the roof cladding having a central section having a curved surface and at least one edge section, which adjoins the central section and whose incline is larger than the incline of the central section and which is transparent to the environment sensor at least in the area of a signal cone of the environment sensor. The environment sensor being at least partially disposed below a roof surface defined by the roof cladding.
    Type: Application
    Filed: August 13, 2020
    Publication date: August 25, 2022
    Inventors: Michael HUELSEN, Dirk LEGLER, Max HUBER, Thomas LINDNER
  • Patent number: 11410353
    Abstract: The invention provides for a medical imaging system (100, 300) comprising a processor (106) for controlling the medical imaging system. Execution of machine executable instructions (112) causes the processor to receive (200) a static angiographic image (114) of a region of interest (322), receive (202) a time series of angiographic images (116, 116?) of the region of interest, construct (204) an image mask (118) using the static angiographic image, determine (206) a time dependent signal (120) for each voxel within the image mask using the time series of angiographic images, construct (208) a composite angiographic image by: assigning (210) a fill time (126) to each voxel within the image mask using an extremum (124) of the time dependent signal if the extremum deviates from an average of the time dependent signal more than a predetermined threshold, and identifying (212) voxels within the image mask as being unfilled voxels.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: August 9, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Michael Gunter Helle, Thomas Lindner
  • Publication number: 20220169314
    Abstract: A roof module for a motor vehicle may have a roof skin, a roof frame on a vehicle body and have at least one transverse frame part extending in the transverse roof direction and a longitudinal frame part extending in the longitudinal roof direction on either side of a longitudinal center roof plane, and a roof opening system having a lid element configured to be displaced on guide rails, which are part of the longitudinal frame parts of the roof frame, in the longitudinal roof direction relative to the roof frame, and/or a solid roof element having a transparent see-through portion and being rigidly connected to the roof frame, having a sensor system comprising at least one sensor module which has at least one environmental sensor and is located outside of the roof opening and/or outside of the transparent see-through portions and is covered by a cover element.
    Type: Application
    Filed: December 4, 2019
    Publication date: June 2, 2022
    Inventors: Michael HUELSEN, Johannes THANNHEIMER, Dirk LEGLER, Max HUBER, Thomas LINDNER, Michael DEPPE, Thomas RUDOLPH, Cedric LANGLAIS, Michael MAILHAMER, Juraj LEHOTSKY, Achim HOLZWARTH, Michael RESPONDEK
  • Publication number: 20210381126
    Abstract: A wafer suitable for epitaxial growth of gallium nitride (GaN) in a Metal Oxide Chemical Vapor Deposition (MOCVD) process. The wafer includes a silicon substrate having a front side and a back side and an edge extending between the front side and the back side, the edge including a front bevel surface connected to the front side and a back bevel surface connected to the back side, wherein the silicon substrate comprises an oxygen denuded silicon layer surrounding a core. The wafer further includes a protection layer being a thermally grown silicon oxide (SiO2) layer substantially covering the front bevel surface and the back bevel surface of the edge, while leaving at least a central region of the front side of the silicon substrate exposed, for preventing meltback during the MOCVD process.
    Type: Application
    Filed: August 25, 2021
    Publication date: December 9, 2021
    Applicant: X-FAB Semiconductor Foundries GmbH
    Inventors: Victor Sizov, Karl-Heinz Stegemann, Ronny Mueller-Biedermann, Thomas Lindner
  • Publication number: 20210274829
    Abstract: A method of treating cut stem tobacco material by expanding the cut stem to provide a first expanded tobacco material having a fill value at least about 10% greater than the fill value of the untreated cut stem tobacco material; intermittently contacting the first expanded tobacco material with a heated surface to provide a second expanded tobacco material with a moisture content of from 0 to about 10% OV and a fill value at least 5% greater than the fill value of the first expanded tobacco material; and (c) adjusting the moisture content of the second expanded tobacco material from about 5% to about 30% OV to provide an expanded product, wherein the fill value of the expanded product is at least 50% greater than the fill value of the untreated cut stem tobacco material when measured at a normalized moisture content of 14.5% OV.
    Type: Application
    Filed: July 10, 2019
    Publication date: September 9, 2021
    Inventors: Dietmar FRANKE, Frank PLUECKHAHN, Matthias LINK, Horst GRZONKA, Thomas LINDNER
  • Patent number: 11089970
    Abstract: A magnetic resonance imaging system (100) for acquiring magnetic resonance data (141) from an imaging zone (108) includes a memory (134, 136) for storing machine executable instructions (150, 152, 154, 156) and pulse sequence commands (140). The pulse sequence commands cause the magnetic resonance imaging system to provide at least one spatially selective saturation pulse (408, 410) to at least one selected volume (124, 124?) that is at least partially outside of a region of interest (123) and within the imaging zone. The magnetic resonance imaging system performs a non-selective inversion (412) of spins in the region of interest followed by a readout (414) of the magnetic resonance data which is reconstructed (202) into an image (142).
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: August 17, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Lindner, Michael Helle
  • Publication number: 20210038749
    Abstract: The present invention relates to a compound of formula (I), a pharmaceutical composition comprising or consisting of said compound, a kit comprising or consisting of said compound or pharmaceutical composition and use of the compound or pharmaceutical composition in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP).
    Type: Application
    Filed: February 6, 2019
    Publication date: February 11, 2021
    Inventors: Uwe HABERKORN, Anastasia LOKTEV, Thomas LINDNER, Walter MIER, Frederik GIESEL, Clemens KRATOCHWIL
  • Publication number: 20200294286
    Abstract: The invention provides for a medical imaging system (100, 300) comprising a processor (106) for controlling the medical imaging system. Execution of machine executable instructions (112) causes the processor to receive (200) a static angiographic image (114) of a region of interest (322), receive (202) a time series of angiographic images (116, 116?) of the region of interest, construct (204) an image mask (118) using the static angiographic image, determine (206) a time dependent signal (120) for each voxel within the image mask using the time series of angiographic images, construct (208) a composite angiographic image by: assigning (210) a fill time (126) to each voxel within the image mask using an extremum (124) of the time dependent signal if the extremum deviates from an average of the time dependent signal more than a predetermined threshold, and identifying (212) voxels within the image mask as being unfilled voxels.
    Type: Application
    Filed: November 29, 2017
    Publication date: September 17, 2020
    Inventors: Michael Gunter Helle, Thomas Lindner
  • Publication number: 20200283503
    Abstract: The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of cancer and angiogenesis related diseases using cyclic peptides.
    Type: Application
    Filed: May 20, 2020
    Publication date: September 10, 2020
    Inventors: Alexandra MATZKE-OGI, Véronique ORIAN-ROUSSEAU, Uwe HABERKORN, Thomas LINDNER, Walter MIER
  • Patent number: 10703796
    Abstract: The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of cancer and angiogenesis related diseases using cyclic peptides.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: July 7, 2020
    Assignees: AMCURE GMBH, RUPRECHT-KARLS-UNIVERSITÄT
    Inventors: Alexandra Matzke-Ogi, Véronique Orian-Rousseau, Uwe Haberkorn, Thomas Lindner, Walter Mier
  • Patent number: 10684341
    Abstract: A method of magnetic resonance imaging (100, 200) includes acquiring (300) tagged magnetic resonance data (144) by controlling the magnetic resonance imaging system with tagging pulse sequence commands (140). The tagging pulse sequence commands include a tagging inversion pulse portion (404) for spin labeling a tagging location (122, 122?) within a subject (118). The tagging pulse sequence commands comprise a phase-contrast readout portion (406) which phase-contrast encodes in at least one direction. The control pulse sequence commands include a control inversion pulse portion (500) and the phase-contrast readout portion. A tagged magnitude image (148) is reconstructed (304) using the tagged magnetic resonance data. A control magnitude image (150) is reconstructed (306) using the control magnetic resonance data. An arterial image (152) is reconstructed (308) by subtracting the control magnitude image and the tagged magnitude image.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: June 16, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Michael Gunter Helle, Thomas Lindner
  • Patent number: 10677871
    Abstract: A medical imaging system (100, 1200) includes a memory (136) for storing machine executable instructions (170), and a processor (130) for controlling the medical imaging system.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: June 9, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Michael Gunter Helle, Thomas Lindner
  • Patent number: 10626527
    Abstract: A method for manufacturing weaving reeds (9) includes forming the dents (1) of the reed (9)where strip- or tape-shaped objects (1) are joined together at a given distance apart (A) in the widthwise direction (B) of the reed (9). At least one of the strip- or tape-shaped objects (1) is provided with a prescribed amount (10-18) of at least one viscous substance applied to its areal surfaces (8), particularly to the end portions (E) thereof, said areal surfaces facing in the widthwise direction (B) of the reed (9), and are then joined together. A device (30) for manufacturing reeds (9), and a reed (9) produced using the aforementioned method is included.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: April 21, 2020
    Assignee: Groz-Beckert KG
    Inventors: Johannes Bruske, Thomas Lindner
  • Patent number: 10618826
    Abstract: Disclosed herein are embodiments of a microscale-based device suitable for purifying fluid, and method of using the device. In particular disclosed embodiments, an electrode layer comprising an enhanced surface area electrode material that has multiple extensions covered in a conductive material are used within the device. The device comprises one or more main flow pathways and one or more side channels. The flow dynamics of the device may be controlled in order to remove contaminants from the fluid. The extensions of the enhanced surface area electrode material are positioned on the surface of the pathways and also may be positioned within the side channels.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 14, 2020
    Assignee: Oregon State University
    Inventors: Goran N. Jovanovic, Chris Loeb, Thomas Lindner, Kevin Drost
  • Publication number: 20190390365
    Abstract: A wafer suitable for epitaxial growth of gallium nitride (GaN) in a Metal Oxide Chemical Vapor Deposition (MOCVD) process. The wafer includes a silicon substrate having a front side and a back side and an edge extending between the front side and the back side, the edge including a front bevel surface connected to the front side and a back bevel surface connected to the back side, wherein the silicon substrate comprises an oxygen denuded silicon layer surrounding a core. The wafer further includes a protection layer being a thermally grown silicon oxide (SiO2) layer substantially covering the front bevel surface and the back bevel surface of the edge, while leaving at least a central region of the front side of the silicon substrate exposed, for preventing meltback during the MOCVD process.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Applicant: X-FAB Semiconductor Foundries GmbH
    Inventors: Victor Sizov, Karl-Heinz Stegemann, Ronny Mueller-Biedermann, Thomas Lindner