Abstract: A hair clipper is provided, including a stator with a plurality of laminations, a bobbin located in operational relation to the stator and having a coil of wire wound around the bobbin, an armature being configured for driving a hair clipper moving blade at one end, and having at least one magnet at an opposite end, the armature having a pivot point, and the motor being configured for operation between 2.5 and 4.2 Volts.

Abstract: A non-pressurized fluid reservoir for a vehicle coolant system includes a bottle configured to store fluid. The bottle has a neck defining an inner circumferential surface that is devoid of threads. The reservoir further includes a cap having a lid and a shank extending from the lid. The shank has an outer circumferential surface and with a spiral ramp supported on the outer circumferential surface to encircle a portion of the shank. The shank is receivable within the neck with the spiral ramp adjacent to the inner circumferential surface to mitigate fluid leaks through the neck.

Abstract: A pivot motor for a hair clipper is provided, including a stator with a plurality of laminations, a bobbin located in operational relation to the stator and having a coil of wire wound around the bobbin, an armature being configured for driving a hair clipper moving blade at one end, and having at least one magnet at an opposite end, the armature having a pivot point, and the motor being configured for operation between 2.5 and 4.2 Volts.

Abstract: The present disclosure generally relates to a flexible frame for use with a flexible container. The frame includes a first member coupled to a second member at a proximal end. The proximal end is configured to be adjacent to a base of the flexible container when the flexible container is received by the frame. The first and second members are configured to provide additional resistance against displacement of the flexible container by an external compression force to increase purchase and control when using the flexible container. In some embodiments, the frame may also assist in efficiently restoring the shape of the flexible container after the compression force is applied and/or provide feedback regarding the extent of the compressive force applied or contortion experienced by the flexible container.

Abstract: Methods for identifying a patient who is eligible for an intensification of heart failure therapy are disclosed. Furthermore, methods for optimizing B-type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy are disclosed. The methods are based on the measurement of the level of at least one marker in a sample from a patient who has heart failure and who receives B-type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy. Further described are kits and devices adapted to carry out the described methods.

Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.

Abstract: A rotor blade for a wind turbine including a first blade segment and a second blade segment extending in opposite directions from a chord-wise joint. Each of the first and second blade segments include one or more shell members and an internal support structure. The internal support structure of the first blade segment includes a beam structure extending between a receiving end and a second end. The internal support structure of the second blade segment includes a receiving section that receives the receiving end of the beam structure of the first blade segment. The rotor blade further includes one or more connection locations where the first and second blade segments are secured together. Moreover, when the beam structure is received within the receiving section, a gap including a varying thickness is defined and maintained between the beam structure and the receiving section in a span-wise direction of the rotor blade.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: This invention relates to a process for producing a recyclable ethylene-vinyl ester polymer comprising reacting an ethylene-vinyl ester polymer having an irreversibly crosslinked structure with a poly(vinyl alcohol) (PVA), via a transesterification reaction, in the presence of a transesterification catalyst, to produce a recyclable ethylene-vinyl ester vitrimer. This invention also relates to a recyclable ethylene-vinyl ester vitrimer prepared according to the process.

Abstract: An eye dropper includes a nozzle secured to a reservoir. The nozzle includes a sleeve that extends around the center and has a first zone, a second zone, and a third zone, having corresponding first, second, and third expansion pressures at which the first, second and third zones separate from the center. The second pressure is less than the first expansion pressure and the third expansion pressure is less than the second expansion pressure. The third expansion pressure may be less than the first expansion pressure. A notch in the sleeve may receive a ridge on the center. The zones may be positioned over a groove in the center or extend completely around a center that is cylindrical or frusto-conical in shape. Multiple instances of first, second and third zones may be distributed along the center. The sleeve may be made of a more flexible material than the center.

Abstract: A dispenser for dispensing a flowable food product from a flexible reservoir is provided. The dispenser includes a frame; a body coupled to the frame and defining a cavity for receiving the flexible reservoir and including a bottom wall defining an opening; and a fitment acceptor at least partly received in the opening. The fitment acceptor includes forward and rearward sidewalls. A radius of curvature of the forward sidewall differs from a radius of curvature of the rearward sidewall. The radius of curvature of the forward sidewall and the radius of the curvature of the rearward sidewall correspond with radiuses of curvature of respective front and rear ends of a fitment of the flexible reservoir such that the fitment of the flexible reservoir is only insertable in the fitment acceptor in one relative orientation between the fitment and the fitment acceptor.

Abstract: The present disclosure provides an imaging optical system. In one aspect, the imaging optical system includes, among other things, a segmented light redirecting element configured to redirect the at least two portions of said electromagnetic radiation into substantially different directions and a segmented light separating element configured to substantially separate electromagnetic radiation into at least two portions.

Abstract: Embodiments herein are directed to a mobility device. The mobility device includes a frame, a pair of foot plates, and a base. The frame has a pair of side rails. The pair of foot plates are pivotally attached to the pair of side rails. Each of the pair of foot plates have a transport surface. The base has an upper surface and an opposite lower surface. The lower surface of the base includes at least one receiving cavity that corresponds to a shape of the pair of foot plates. The base is positioned on the transport surface to receive the pair of foot plates within the at least one receiving cavity and is configured to receive a plurality of cargo containers on the upper surface.

Abstract: A powered wheelchair apparatus includes a chair component, a power base component and a wheelchair control system. The wheelchair control system includes a processor and a user input device communicatively coupled to the processor. A display is communicatively coupled to the processor. A memory module is communicatively coupled to the processor that stores logic that, when executed by the processor, causes the system to receive user instructions from the user input device and display a message on the display based on the user instructions. The display is on a back of the chair component.

Abstract: The disclosure relates to therapeutic compositions comprising isolated bacteria useful in the treatment of ulcerative colitis or Crohn's disease. Related methods and uses are also disclosed.

Abstract: A system including an optical system having at least one refractive or reflective element, the optical system configured to substantially receive electromagnetic radiation emanating from a source, the optical system being located within a Dewar, a support structure, support structure being mechanically disposed between the optical system and a surface of the Dewar, the support structure having substantially low thermal conductance, a cold source; the cold source being located within the Dewar, a thermal link, the thermal link being mechanically disposed between the optical system and the cold source, the thermal link being substantially flexible and having substantially high thermal conductance.