Patents by Inventor Thomas A. Purcell

Thomas A. Purcell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4701466
    Abstract: Compounds of general formula ##STR1## in which R.sub.1, taken separately, denotes a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group, andR.sub.2, taken separately, denotes a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group or a phenylthio or phenylsulphonyl group, or alternativelyR.sub.1 and R.sub.2 together form an ethano bridge or, together with the two carbon atoms 8 and 9, form a fused benzene ring,R.sub.3 denotes a hydrogen atom or a methyl group andR.sub.4 denotes a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group or a cation of a base which is acceptable in pharmacology, the group CH(R.sub.3)COOR.sub.4 being at position 2 or 3. have uses in treatment of inflammation, pain and undesirable platelet aggregation.
    Type: Grant
    Filed: April 10, 1986
    Date of Patent: October 20, 1987
    Assignee: Synthelabo
    Inventors: Thomas Purcell, Lydia Zard
  • Patent number: 4492709
    Abstract: Imidazolidine derivatives of the formula: ##STR1## wherein R.sub.1 represents the hydroxy radical and R.sub.2 represents a grouping --NHSO.sub.2 CH.sub.3, --NHCOR' or --NHCONR'R", R' and R" independently of one another representing a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, or alternatively R.sub.2 represents the hydroxy radical and R.sub.1 represents a grouping --NHSO.sub.2 CH.sub.3, --NHCOR' or ?NHCONR'R", R' and R" independently of one another representing a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, and pharmacologically-acceptable acid addition salts thereof, are new therapeutically useful compounds. They are more particularly useful in the treatment of gastric hypersecretion or hyperacidity or glaucoma.
    Type: Grant
    Filed: January 25, 1983
    Date of Patent: January 8, 1985
    Assignee: Synthelabo
    Inventor: Thomas A. Purcell
  • Patent number: 4342759
    Abstract: A method of treating a patient susceptible to thrombosis is provided which comprises treating the said patient with a compound of the formula ##STR1## wherein R' is H or CH.sub.3R is a ##STR2## radical in which Z is 0, S, SO, SO.sub.2 or NR.sub.1, R.sub.1 being H, C.sub.6 H.sub.5, CH.sub.3, CONR.sub.2 R.sub.3, COOR.sub.2, COR.sub.2 or SO.sub.2 R.sub.2, where R.sub.2 and R.sub.3 are, independently, H, C.sub.1-4 alkyl, C.sub.6 H.sub.5 or CF.sub.3.
    Type: Grant
    Filed: August 19, 1980
    Date of Patent: August 3, 1982
    Assignee: Synthelabo
    Inventors: Thomas A. Purcell, Braham Shroot, Daniel Galtier
  • Patent number: 4243665
    Abstract: Compounds corresponding to the formula ##STR1## in which R' is a hydrogen atom or a methyl radical and R represents a radical ##STR2## in which Z is O, S, S.fwdarw.O, SO.sub.2 or NR.sub.1, in which R.sub.1 is a hydrogen atom or an alkyl, CONR.sub.2 R.sub.3, COOR.sub.2, COR.sub.2 or SO.sub.2 R.sub.2 radical, R.sub.2 and R.sub.3 each representing, independently of one another, a hydrogen atom, an alkyl radical having 1 to 4 carbon atoms, a phenyl radical or a CF.sub.3 radical, in the form of racemates or enantiomers if R' is CH.sub.3, and also, where appropriate, their addition salts with pharmaceutically acceptable acids.The compounds and salts are useful as anti-inflammatory agents, e.g. for treatment of arthritis. A process for preparing them and pharmaceutical compositions containing them are also claimed.
    Type: Grant
    Filed: November 21, 1978
    Date of Patent: January 6, 1981
    Assignee: Synthelabo
    Inventors: Thomas A. Purcell, Braham Shroot, Daniel J. M. Galtier