Abstract: Computer and mobile device-based systems and computer-implemented methods are described for automated medication adherence improvement for patients in medication-assisted treatments. The computer and mobile device-based systems includes modules and components to help patients in identifying prescribed medications, logging medication events, and to provide patients with personalized and targeted adherence enhancing interventions consisting of short questions, tips, advices, suggestions, strategies etc. by applying data mining and statistical analysis techniques on the individual and population-level data collected primarily from the same system.

Abstract: A passive sensor that is located on or adjacent to a structure that can be used to monitor the affect of environment on a structure or coating that is used to protect the structure. The sensor includes a parasitic element that interacts with the environment and influences the intensity of the electromagnetic response between the inductive element of the sensor and the antenna of the interrogation reader device. The condition of the parasitic element is determined by the radio frequency interaction of the reader antenna and the inductive element of the sensor. The parasitic element condition correlates to the environmental severity, or corrosivity of the environment and damage to metallic structures or protective coatings. An integrated circuit within the sensor is capable of storing identification, time, material, and measurement information. The sensor and system of the present invention is useful for tracking and monitoring cumulate environmental damage to a structure.

Abstract: Sensors, methods and systems detect physical effects (e.g., corrosion, erosion, scaling and/or oxidation) of a fluid in contact with a diaphragm associated with a sensor assembly. The diaphragm preferably exhibits a first mechanical response when initially placed into contact with a fluid and a second mechanical response different from the first mechanical response after exposure to the fluid for a predetermined period of time. A change in the diaphragm mechanical responses between at least the first and second mechanical responses is therefore indicative of physical effects on the diaphragm over time caused by the fluid in contact therewith. A mechanical response sensor is operatively associated with the diaphragm so as to measure the change in the diaphragm mechanical responses and thereby determine the physical effects over time of the fluid in contact with the diaphragm.

Abstract: A passive sensor that is located on or adjacent to a structure that can be used to monitor the affect of environment on a structure or coating that is used to protect the structure. The sensor includes a parasitic element that interacts with the environment and influences the intensity of the electromagnetic response between the inductive element of the sensor and the antenna of the interrogation reader device. The condition of the parasitic element is determined by the radio frequency interaction of the reader antenna and the inductive element of the sensor. The parasitic element condition correlates to the environmental severity, or corrosivity of the environment and damage to metallic structures or protective coatings. An integrated circuit within the sensor is capable of storing identification, time, material, and measurement information. The sensor and system of the present invention is useful for tracking and monitoring cumulate environmental damage to a structure.

Abstract: Sensors, methods and systems detect physical effects (e.g., corrosion, erosion, scaling and/or oxidation) of a fluid in contact with a diaphragm associated with a sensor assembly. The diaphragm preferably exhibits a first mechanical response when initially placed into contact with a fluid and a second mechanical response different from the first mechanical response after exposure to the fluid for a predetermined period of time. A change in the diaphragm mechanical responses between at least the first and second mechanical responses is therefore indicative of physical effects on the diaphragm over time caused by the fluid in contact therewith. A mechanical response sensor is operatively associated with the diaphragm so as to measure the change in the diaphragm mechanical responses and thereby determine the physical effects over time of the fluid in contact with the diaphragm.

Abstract: Integral fiber optic-based condition sensors detect conditions of a composite structure, e.g., a coated wire assembly so as to detect damage or conditions that may damage the same. Preferably, at least one optical fiber sensor having a plurality of Bragg gratings written into the fiber at spaced-apart locations along its axial length is integrated into the electrical insulator coating of a wire, wire bundle or wiring harness. The fiber optic sensor may thus be employed to measure the environmental loads on the electrical wiring including stresses from bending, axial loading, pinch points, high temperature excursions and chemical damage. The system is capable of detecting and locating transient conditions that might cause damage to a wiring system or permanent changes in state associated with damage events. The residual stress in the electrical insulator coating of a wire, wire bundle, or wiring harness are used to monitor the evolution of damage by wear or chaffing processes.

Abstract: The present invention relates to methods of and apparatus for rapidly and accurately measuring the temperature of a small volume sample. The remote temperature sensor contains an optical interferometric sensor, preferably an extrinsic Fabry-Perot interferometer (EFPI), for measuring the difference in the distance traveled by a reference reflection and a sensing reflection. Because the refraction index of a solution is proportional to temperature, the output of the optical interferometric sensor can be converted to a temperature with a standard curve. Further, the present invention also provides methods and apparatus for measuring the temperature of the sample in performing non-contact (remote) thermocycling on small, micro to nanoliter, volume samples, wherein each cycle can be completed in as little as a few seconds.

Abstract: The present invention is directed toward an interferometric sensor that permits the simultaneous measurement of a change in more than one environmental condition. The interferometric sensor comprises an optical fiber and a plurality of sensing regions positioned in an operable relationship to the optical fiber. Each sensing region has partially reflective boundaries and produces an interferometric signal.

Abstract: A fiber optic system and method of use is disclosed. The fiber optic system comprises a laminated, pre-stressed, piezoelectric actuator; and a fiber optic strain gage having an input/output fiber, wherein the fiber optic strain gage is attached to a surface of the laminated, pre-stressed, piezoelectric actuator. The fiber optic system is useful for performing dynamic mechanical analysis on a sample.

Abstract: A body implantable sensor for sensing pressure in an environment within internal body tissue is described. In an implementation, the sensor includes a housing, an optical waveguide and a diaphragm with a reflective surface that faces a waveguide distal end and that reflects at least a portion of the signals exiting the waveguide distal end back into the waveguide. The diaphragm is movable relative to the waveguide end. The distance between the waveguide distal end and the diaphragm reflective surface is determined by pressure forces acting on a sensing surface of the diaphragm that is opposite the reflective surface. A cover surrounds the diaphragm and protects it from impingement, but leaves the diaphragm sensing surface exposed to pressure forces. In some implementations, an attachment mechanism stabilizes the sensor when implanted in the bodily tissue.

Abstract: A single-ended long period grating optical device is presented. The single-ended optical device comprises an optical waveguide having at least one core mode and a plurality of cladding modes. At least one long period grating couples light from the core mode to the cladding modes. A reflector is positioned in an operable relationship to the long period grating, and the reflector reflects a signal. A mode stripper is positioned after the long period grating and removes the cladding modes from a transmitted signal and the reflected signal.