Patents by Inventor Thomas A. Yager
Thomas A. Yager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120251897Abstract: A method to produce an aluminium air battery, comprising: forming a selectively reactive coating on a surface of an anode core to form a composite anode, the selectively reactive coating comprising a zinc alloy and the anode core comprising aluminium; and storing an electrolyte in contact with the composite anode, wherein the selectively reactive coating is capable of chemically reacting with the electrolyte during discharging of the aluminium air battery the reactive coating may also include an anode corrosion inhibitor material consisting of one or more of indium, gallium, lead, thallium or mercuryType: ApplicationFiled: September 30, 2010Publication date: October 4, 2012Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLCInventors: Thomas A. Yager, Ezekiel Kruglick
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Publication number: 20120234730Abstract: A method of separating material includes providing a mixture of a first material, such as a semiconductor, and a second material, such as an insulator or a different semiconductor. The mixture can be irradiated using a light source at a wavelength that causes the first material's conductivity to increase while leaving the second material's conductivity (substantially) unchanged. Placing the mixture in contact with a ground electrode discharges the first material but not the second material due the difference in their conductivities. Applying an electric field to the discharged mixture separates the discharged first material from the second material.Type: ApplicationFiled: March 18, 2011Publication date: September 20, 2012Inventor: Thomas A. Yager
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Patent number: 8258284Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in blood and useful in diagnosing schizophrenia and/or bipolar disorder as well as monitoring therapeutic efficacy of treatment for schizophrenia or bipolar disorder. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention can be used to diagnose schizophrenia and/or bipolar disorder. Measurement of the expression level of products of biomarkers of the invention using polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are compositions and kits containing said polynucleotides and proteins. Further encompassed by the invention is the use of the polynucleotides and proteins to monitor the efficacy of therapeutic regimens.Type: GrantFiled: May 10, 2010Date of Patent: September 4, 2012Assignee: GeneNews, Inc.Inventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao
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Patent number: 8249814Abstract: Disclosed is a method of testing for colorectal cancer in a test individual by providing data corresponding to a level of products of selected biomarkers and applying the data to a formula to provide an indication of whether the test individual has colorectal cancer. Also disclosed are kits for measuring data corresponding to the products of selected biomarkers, and kits and methods of monitoring therapeutic efficacy of treatments for colorectal cancer.Type: GrantFiled: October 23, 2006Date of Patent: August 21, 2012Assignee: GeneNews Inc.Inventors: Choong-Chin Liew, Mark Han, Thomas Yager, Samuel Chao, Run Zheng, Hongwei Zhang
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Patent number: 8239136Abstract: In one aspect the invention is a method of testing for one or more colorectal pathologies or one or more subtypes of colorectal pathology (in one embodiment colorectal cancer) in a test individual by providing data corresponding to a level of products of selected biomarkers and applying the data to a formula to provide an indication of whether the test individual has one or more colorectal pathologies or one or more subtypes of colorectal pathology. In some aspects the method is computer based and a computer applies the data to the formula. In other aspects a computer system is configured with instructions that cause the processor to provide a user with the indication of whether the test individual has colorectal pathology. Also encompassed are kits for measuring data corresponding to the products of selected biomarkers which in some embodiments include a computer readable medium. Also encompassed are kits and methods of monitoring therapeutic efficacy of treatments for one or more colorectal pathologies.Type: GrantFiled: October 23, 2006Date of Patent: August 7, 2012Assignee: GeneNews Inc.Inventors: Choong-Chin Liew, Mark Han, Thomas Yager, Samuel Chao, Run Zheng, Hongwei Zhang
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Publication number: 20120082907Abstract: Implementations and techniques for rechargeable zinc air batteries are generally disclosed.Type: ApplicationFiled: September 30, 2010Publication date: April 5, 2012Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLCInventor: Thomas A. Yager
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Publication number: 20120082921Abstract: Implementations and techniques for metal air batteries including a composite anode are generally disclosed.Type: ApplicationFiled: September 30, 2010Publication date: April 5, 2012Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLCInventors: Ezekiel Kruglick, Thomas A. Yager, Seth Adrian Miller
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Publication number: 20120077094Abstract: Implementations and techniques for employing cathode tubes in metal air battery devices or systems are generally disclosed.Type: ApplicationFiled: September 28, 2010Publication date: March 29, 2012Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLCInventors: Thomas A. Yager, Seth Adrian Miller
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Patent number: 8142998Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in osteoarthritis and/or in a particular stage of osteoarthritis, as well as a means of selecting the novel biomarker combinations. The measurement of expression of the products of the biomarkers and combinations of biomarkers demonstrates particular advantage in one or more of the following: (a) diagnosing individuals as having arthritis, (b) differentiating between two stages of osteoarthritis (OA) and (c) diagnosing individuals as having a particular stage of OA. Polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers are within the scope of the invention as are kits containing the polynucleotides and proteins and the use of the polynucleotides and proteins.Type: GrantFiled: September 4, 2009Date of Patent: March 27, 2012Assignee: GeneNews, Inc.Inventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao, Hongwei Zhang, Wayne Marshall
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Publication number: 20120047665Abstract: The present technology provides an illustrative method for dyeing textiles that includes intermixing a dye with super-critical carbon dioxide (sc-CO2) to form a dye solution and immersing a fabric in the dye solution. The method further includes applying an electric field to the dye solution to cause charged particles of the dye solution to separate and cause the dye to diffuse into the fabric.Type: ApplicationFiled: August 27, 2010Publication date: March 1, 2012Applicant: Empire Technology Development LLCInventor: Thomas A. Yager
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Publication number: 20110234240Abstract: Technologies are generally described for monitoring dehydration levels of a subject using Radio Frequency (RF) dielectric resonant oscillators (DROs) that may be affixed to the skin of the subject. According to some example aspects, a sensor comprising a microstrip ring resonator may be affixed to the skin and used to determine the change in hydration of a person quantitatively and/or qualitatively. An RF emitter can be configured to emit a scanning signal to the sensor, where the scanning signal can be swept over a specified frequency range. The sensor is configured to resonate in response to the scanning signal, where characteristics of the sensor's resonance (e.g., the specific frequency and “Q” factor of the resonance) is impacted by dielectric losses of the sensor to the skin due to hydration level of the subject.Type: ApplicationFiled: March 23, 2010Publication date: September 29, 2011Applicant: Empire Technology Development, LLCInventor: Thomas A. Yager
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Publication number: 20110224479Abstract: Technologies are generally described for hyperthermia based treatment of diseased tissues using conductive particles. Conductive particles of known composition and size distribution may be implanted in diseased tissue and exposed to an alternating magnetic field, which may be tuned to the size of the metal particles to induce eddy currents producing heat in the implanted particles. As the temperature of the metal particles increases, their resistance also increases due to their positive temperature coefficient of resistivity. An antenna placed externally to the body near metal particles may be part of a tuned RF circuit and scanned for resonance. The change either in resonance frequency or circuit impedance may provide tuned feedback, which may be used to control the hyperthermia treatment.Type: ApplicationFiled: March 11, 2010Publication date: September 15, 2011Applicant: Empire Technology Development, LLCInventor: Thomas A. Yager
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Patent number: 7991557Abstract: The present invention provides systems and method for constructing classifiers that distinguish between trait subgroups using molecular marker data from blood samples. The invention further encompasses the use of the classifiers and combinations of molecular markers identified by the classifiers in a wide variety of applications including: diagnosis; prognosis; prediction of disease, stage of disease or disease risk; monitoring disease progression and/or regression; monitoring disease reoccurrence and identifying risk of disease reoccurrence; determining and/or predicting response to treatment and/or treatment outcomes; monitoring and/or predicting treatment compliance or non compliance and the like. The invention further provides a variety of selected molecular markers and a means to identify combinations of the selected molecular markers useful for diagnosing particular traits of interest.Type: GrantFiled: June 20, 2005Date of Patent: August 2, 2011Assignee: Genenews CorporationInventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao
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Publication number: 20110020809Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in individuals with mild osteoarthritis as compared with individuals without osteoarthritis. Polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are kits containing said polynucleotides and proteins for use in diagnosing mild osteoarthritis. Further encompassed by the invention is the use of the polynucleotides and proteins which specifically and/or selectively hybridize to the product of the biomarkers of the invention to monitor disease regression in an individual and to monitor the efficacy of therapeutic regimens. The invention also provides for methods of using the products of the biomarkers of the invention in the identification of novel therapeutic targets for osteoarthritis.Type: ApplicationFiled: May 10, 2010Publication date: January 27, 2011Inventors: Choong-Chin Liew, Hongwei Zhang, Adam Dempsey, Thomas Yager, Samuel Chao
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Publication number: 20110020808Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in blood and useful in diagnosing schizophrenia and/or bipolar disorder as well as monitoring therapeutic efficacy of treatment for schizophrenia or bipolar disorder. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention can be used to diagnose schizophrenia and/or bipolar disorder. Measurement of the expression level of products of biomarkers of the invention using polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are compositions and kits containing said polynucleotides and proteins. Further encompassed by the invention is the use of the polynucleotides and proteins to monitor the efficacy of therapeutic regimens.Type: ApplicationFiled: May 10, 2010Publication date: January 27, 2011Inventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao
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Publication number: 20100143916Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in osteoarthritis and/or in a particular stage of osteoarthritis, as well as a means of selecting the novel biomarker combinations. The measurement of expression of the products of the biomarkers and combinations of biomarkers of the invention demonstrates particular advantage in one or more of the following: (a) diagnosing individuals as having arthritis, (b) differentiating between two stages of osteoarthritis (OA) and (c) diagnosing individuals as having a particular stage of osteoarthritis (OA).Type: ApplicationFiled: September 4, 2009Publication date: June 10, 2010Inventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao, Hongwei Zhang, Wayne Marshall
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Patent number: 7713695Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in individuals with mild osteoarthritis as compared with individuals without osteoarthritis. Polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are kits containing said polynucleotides and proteins for use in diagnosing mild osteoarthritis. Further encompassed by the invention is the use of the polynucleotides and proteins which specifically and/or selectively hybridize to the product of the biomarkers of the invention to monitor disease regression in an individual and to monitor the efficacy of therapeutic regimens. The invention also provides for methods of using the products of the biomarkers of the invention in the identification of novel therapeutic targets for osteoarthritis.Type: GrantFiled: February 6, 2006Date of Patent: May 11, 2010Assignee: GeneNews, Inc.Inventors: Choong-Chin Liew, Hongwei Zhang, Adam Dempsey, Thomas Yager, Samuel Chao
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Patent number: 7713702Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in blood and useful in diagnosing schizophrenia and/or bipolar disorder as well as monitoring therapeutic efficacy of treatment for schizophrenia or bipolar disorder. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention can be used to diagnose schizophrenia and/or bipolar disorder. Measurement of the expression level of products of biomarkers of the invention using polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are compositions and kits containing said polynucleotides and proteins. Further encompassed by the invention is the use of the polynucleotides and proteins to monitor the efficacy of therapeutic regimens.Type: GrantFiled: October 10, 2008Date of Patent: May 11, 2010Assignee: GeneNews CorporationInventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao
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Publication number: 20090208942Abstract: In one aspect the invention is a method of testing for one or more colorectal pathologies or one or more subtypes of colorectal pathology (in one embodiment colorectal cancer) in a test individual by providing data corresponding to a level of products of selected biomarkers and applying the data to a formula to provide an indication of whether the test individual has one or more colorectal pathologies or one or more subtypes of colorectal pathology. In some aspects the method is computer based and a computer applies the data to the formula. In other aspects a computer system is configured with instructions that cause the processor to provide a user with the indication of whether the test individual has colorectal pathology. Also encompassed are kits for measuring data corresponding to the products of selected biomarkers which in some embodiments include a computer readable medium. Also encompassed are kits and methods of monitoring therapeutic efficacy of treatments for one or more colorectal pathologies.Type: ApplicationFiled: October 23, 2006Publication date: August 20, 2009Applicant: GENENEWS INC.Inventors: Choong-Chin Liew, Mark Han, Thomas Yager, Samuel Chao, Run Zheng, Hongwei Zhang
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Publication number: 20090098564Abstract: The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in blood and useful in diagnosing schizophrenia and/or bipolar disorder as well as monitoring therapeutic efficacy of treatment for schizophrenia or bipolar disorder. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention can be used to diagnose schizophrenia and/or bipolar disorder. Measurement of the expression level of products of biomarkers of the invention using polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are compositions and kits containing said polynucleotides and proteins. Further encompassed by the invention is the use of the polynucleotides and proteins to monitor the efficacy of therapeutic regimens.Type: ApplicationFiled: October 10, 2008Publication date: April 16, 2009Inventors: Choong-Chin Liew, Thomas Yager, Adam Dempsey, Samuel Chao