Abstract: The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity molecule. In addition, the invention provides glass microbubbles coated with an affinity molecule. Methods of using the microbubbles of the invention for isolating analytes and cells are specifically provided.

Abstract: The invention relates to an improved process for preparing pradofloxacin, in which the substituent in the 7 position is introduced by nucleophilic substitution in an N-methylpyrrolidone-ethanol solvent mixture.

Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.

Abstract: The present invention provides novel binding pair compositions of defined and limited stability comprising nucleic acid detection markers useful for the homogeneous, sensitive detection of analytes. Also provided are methods for the sensitive homogeneous detection of analytes, particularly analytes of clinical relevance. Kits for preparing binding pairs of the invention and for performing the methods of the invention are also provided.

Abstract: The present invention provides novel binding pair compositions of defined and limited stability comprising nucleic acid detection markers useful for the homogeneous, sensitive detection of analytes. Also provided are methods for the sensitive homogenous detection of analytes, particularly analytes of clinical relevance. Kits for preparing binding pairs of the invention and for performing the methods of the invention are also provided.

Abstract: A sealing gasket includes a liner and a polyurethane foam layer disposed on the liner. The polyurethane foam layer can have a density of 50 kg/m3 to 250 kg/m3, a force-to-compress at 25% compression of not greater than 5.0 psi, and an 50% springback parameter of not greater than 2.0 seconds. The polyurethane foam has a thickness in a range of 0.3 mm to 10.0 mm. A surface of the polyurethane foam layer has a skin.

Abstract: A torque transmitting apparatus includes a cover portion generally defined by a first axis. The cover portion includes a plurality of adjustment apertures. The apparatus also includes a flywheel coupled to the cover portion for rotation therewith, wherein the flywheel is restrained from axial movement relative to the cover portion. The apparatus also includes a pressure plate coupled to the cover portion for rotation therewith. The pressure plate is axially moveable relative to the cover portion. The apparatus also includes a clutch disk at least partially interposed between the flywheel and the pressure plate. The apparatus also includes a plurality of first members extending between the pressure plate and the cover. Each first member exerts a biasing outward radial force on the adjustment aperture to resist axial movement therebetween. A portion of the first member exerts a biasing axial force on the pressure plate thereby biasing the pressure plate toward the flywheel.

Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.

Abstract: The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity molecule. In addition, the invention provides glass microbubbles coated with an affinity molecule. Methods of using the microbubbles of the invention for isolating analytes and cells are specifically provided.

Abstract: The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity molecule. In addition, the invention provides glass microbubbles coated with an affinity molecule. Methods of using the microbubbles of the invention for isolating analytes and cells are specifically provided.

Abstract: Systems and methods of controlling a messaging system are provided. A particular method includes generating an n-times-use network address to access a control interface in response to receipt of a message addressed to a subscriber at a messaging system. The method further includes determining a notification address associated with the subscriber and generating a notification message addressed to the notification address. The notification message includes at least a portion of content of the message and the n-times-uses network address. The n-times-use network address is selectable a predetermined number of times at a browser application to send a control message to the control interface to control disposition of the message.

Abstract: A system for managing battery temperature is described. The system may include a cooling system which may include a fluid. A cabin circulation subsystem may be coupled to the cooling subsystem and may utilize the fluid for cabin cooling. A separate battery circulation subsystem may also may also be coupled to the cooling subsystem so that it may additionally utilize the fluid for battery cooling. A control may be present in order to regulate movement of the fluid to the cabin circulation subsystem and/or to the battery circulation subsystem.

Abstract: Porous ceramic diesel particulate filters are regenerated to combust accumulated carbon particulates trapped therein through a controlled regeneration process wherein heat is input to the filter at a ramped or staged heating rate below that rate at which the particulate combustion process would proceed so rapidly and extensively that filter temperatures would be raised to filter-damaging levels.

Abstract: Briefly described, embodiments of this disclosure include methods of recovering bio-oil products, fuels, diesel fuels, and the like are disclosed.

Abstract: A torque transmitting apparatus includes a cover portion generally defined by a first axis. The cover portion includes a plurality of adjustment apertures. The apparatus also includes a flywheel coupled to the cover portion for rotation therewith, wherein the flywheel is restrained from axial movement relative to the cover portion. The apparatus also includes a pressure plate coupled to the cover portion for rotation therewith. The pressure plate is axially moveable relative to the cover portion. The apparatus also includes a clutch disk at least partially interposed between the flywheel and the pressure plate. The apparatus also includes a plurality of first members extending between the pressure plate and the cover. Each first member exerts a biasing outward radial force on the adjustment aperture to resist axial movement therebetween. A portion of the first member exerts a biasing axial force on the pressure plate thereby biasing the pressure plate toward the flywheel.

Abstract: The invention relates to an improved process for preparing pradofloxacin, in which the substituent in the 7 position is introduced by nucleophilic substitution in an N-methylpyrrolidone-ethanol solvent mixture.

Abstract: Systems and methods of controlling a messaging system are provided. A particular method includes generating an n-times-use network address to access a control interface in response to receipt of a message addressed to a subscriber at a messaging system. The method further includes determining a notification address associated with the subscriber and generating a notification message addressed to the notification address. The notification message includes at least a portion of content of the message and the n-times-uses network address. The n-times-use network address is selectable a predetermined number of times at a browser application to send a control message to the control interface to control disposition of the message.

Abstract: This invention describes compositions and methods for use in PSA assays having low functional sensitivity which are useful, for example, in the detection of early stage recurrence of prostate disease following treatment and in the determination of whether patients have early stage biochemical reoccurrence (ES-BCR) or stable disease.

Abstract: Porous ceramic diesel particulate filters are regenerated to combust accumulated carbon particulates trapped therein through a controlled regeneration process wherein heat is input to the filter at a ramped or staged heating rate below that rate at which the particulate combustion process would proceed so rapidly and extensively that filter temperatures would be raised to filter-damaging levels.